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- W2035326073 abstract "RATIONALE: Factors related to food sensitization have not been extensively explored in diverse birth cohorts. Breastfeeding, early exposure to supplementary food (SF < 4months), and African-American (AA) race are potential risk factors for food sensitization. We explored the association of these factors to egg, milk, and peanut sensitization at 2 years using the WHEALS birth cohort. METHODS: Mothers were interviewed at 1, 6, and 12 months about infant feeding and age at exposure to foods supplementary to breastfeeding and formula. Blood samples were collected at infant age 2 years to measure IgE. Food sensitization (food-IgE) was defined as serum IgE for milk, egg, or peanut 0.35 UL/ml or greater. RESULTS: 249 maternal-infant pairs were included in this analysis. Mean age of cohort mothers was 30.0 years and 49% were AA. Prevalence of any food-IgE was 35.7%, 30.9% of mothers reported SF6months. In bivariate analyses, SF < 4months and breastfeeding were not related to food IgE, but the Relative Risk (95% Confidence Interval) for AA race and food-IgE was 1.4 (1.0-1.9), and was 1.6 (1.0-2.7) for egg, p = 0.03; 1.6 (1.0-2.4) for milk, p = 0.04 and 2.0 (1.0-4.3) for peanut, p = 0.06. In multivariable analysis, only AA race was significantly related to food IgE (p = 0.01). CONCLUSIONS: In this study population, AA race was the only variable related to food-IgE at 2 years." @default.
- W2035326073 created "2016-06-24" @default.
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- W2035326073 date "2009-02-01" @default.
- W2035326073 modified "2023-09-25" @default.
- W2035326073 title "Exploring Risk Factors for Food Sensitization in a Racially Diverse Birth Cohort" @default.
- W2035326073 doi "https://doi.org/10.1016/j.jaci.2008.12.394" @default.
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