FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035338836> ?p ?o ?g. }

• W2035338836 endingPage "623" @default.
• W2035338836 startingPage "617" @default.
• W2035338836 abstract "Rabbit antibodies to bovine fibrinogen were used to study the antigenic activity of four cyanogen bromide peptides containing the disulfide regions of this molecule. In precipitation tests the highest activity was associated with the peptide F-CB3 which is exclusively derived from the α-chain. Reduction of the single disulfide bridge in peptide F-CB3 did not influence its serologic activity. Weaker reactions were observed with the N-terminal multichain peptide F-CB1. The antigenicity of peptide F-CB1 was not affected by removal of fibrinopeptides A and B but it was lost after reduction. The immunological activity of the multichain peptide F-CB2 was even less than that of peptide F-CB1 and the antigenic determinants were destroyed by reduction. A large fragment essentially composed of peptides F-CB1 and F-CB2 could be obtained by limited cyanogen bromide cleavage and showed considerably better immunological activity than peptides F-CB1 and F-CB2 together. Apparently no activity was associated with a mixture of small hydrophobic, disulfide-loop peptides tentatively called peptide F-CB4. The large loss of antigenic activity in cyanogen bromide digests of fibrinogen suggests that the disulfide-stabilized regions do not have an important role in maintaining conformational antigenic determinants of fibrinogen. Changes in noncovalently stabilized conformation requiring uncleaved chains is considered as a possible reason for the findings observed." @default.
• W2035338836 created "2016-06-24" @default.
• W2035338836 creator A5006577753 @default.
• W2035338836 creator A5064803768 @default.
• W2035338836 creator A5078385571 @default.
• W2035338836 date "1975-02-01" @default.
• W2035338836 modified "2023-10-14" @default.
• W2035338836 title "Antigenic Determinants in the Disulfide Regions of Bovine Fibrinogen" @default.
• W2035338836 cites W1483507325 @default.
• W2035338836 cites W1532577754 @default.
• W2035338836 cites W1588733323 @default.
• W2035338836 cites W1974808520 @default.
• W2035338836 cites W1992896821 @default.
• W2035338836 cites W2014401062 @default.
• W2035338836 cites W2015236450 @default.
• W2035338836 cites W2021564474 @default.
• W2035338836 cites W2024558695 @default.
• W2035338836 cites W2029786429 @default.
• W2035338836 cites W2034880458 @default.
• W2035338836 cites W2041056373 @default.
• W2035338836 cites W2059723436 @default.
• W2035338836 cites W2075009329 @default.
• W2035338836 cites W2081816235 @default.
• W2035338836 cites W2093147401 @default.
• W2035338836 cites W2094777384 @default.
• W2035338836 cites W2096674223 @default.
• W2035338836 cites W2161983723 @default.
• W2035338836 cites W2176634966 @default.
• W2035338836 cites W2315788934 @default.
• W2035338836 cites W3023179216 @default.
• W2035338836 cites W4247829566 @default.
• W2035338836 cites W4322154075 @default.
• W2035338836 doi "https://doi.org/10.1111/j.1432-1033.1975.tb03964.x" @default.
• W2035338836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/50233" @default.
• W2035338836 hasPublicationYear "1975" @default.
• W2035338836 type Work @default.
• W2035338836 sameAs 2035338836 @default.
• W2035338836 citedByCount "11" @default.
• W2035338836 crossrefType "journal-article" @default.
• W2035338836 hasAuthorship W2035338836A5006577753 @default.
• W2035338836 hasAuthorship W2035338836A5064803768 @default.
• W2035338836 hasAuthorship W2035338836A5078385571 @default.
• W2035338836 hasBestOaLocation W20353388361 @default.
• W2035338836 hasConcept C104317684 @default.
• W2035338836 hasConcept C147483822 @default.
• W2035338836 hasConcept C151730666 @default.
• W2035338836 hasConcept C159654299 @default.
• W2035338836 hasConcept C167625842 @default.
• W2035338836 hasConcept C175156509 @default.
• W2035338836 hasConcept C181199279 @default.
• W2035338836 hasConcept C185592680 @default.
• W2035338836 hasConcept C195616568 @default.
• W2035338836 hasConcept C203014093 @default.
• W2035338836 hasConcept C27256138 @default.
• W2035338836 hasConcept C2777093645 @default.
• W2035338836 hasConcept C2779026604 @default.
• W2035338836 hasConcept C2779201268 @default.
• W2035338836 hasConcept C2779281246 @default.
• W2035338836 hasConcept C2910051704 @default.
• W2035338836 hasConcept C43369102 @default.
• W2035338836 hasConcept C55493867 @default.
• W2035338836 hasConcept C71240020 @default.
• W2035338836 hasConcept C86803240 @default.
• W2035338836 hasConceptScore W2035338836C104317684 @default.
• W2035338836 hasConceptScore W2035338836C147483822 @default.
• W2035338836 hasConceptScore W2035338836C151730666 @default.
• W2035338836 hasConceptScore W2035338836C159654299 @default.
• W2035338836 hasConceptScore W2035338836C167625842 @default.
• W2035338836 hasConceptScore W2035338836C175156509 @default.
• W2035338836 hasConceptScore W2035338836C181199279 @default.
• W2035338836 hasConceptScore W2035338836C185592680 @default.
• W2035338836 hasConceptScore W2035338836C195616568 @default.
• W2035338836 hasConceptScore W2035338836C203014093 @default.
• W2035338836 hasConceptScore W2035338836C27256138 @default.
• W2035338836 hasConceptScore W2035338836C2777093645 @default.
• W2035338836 hasConceptScore W2035338836C2779026604 @default.
• W2035338836 hasConceptScore W2035338836C2779201268 @default.
• W2035338836 hasConceptScore W2035338836C2779281246 @default.
• W2035338836 hasConceptScore W2035338836C2910051704 @default.
• W2035338836 hasConceptScore W2035338836C43369102 @default.
• W2035338836 hasConceptScore W2035338836C55493867 @default.
• W2035338836 hasConceptScore W2035338836C71240020 @default.
• W2035338836 hasConceptScore W2035338836C86803240 @default.
• W2035338836 hasIssue "2" @default.
• W2035338836 hasLocation W20353388361 @default.
• W2035338836 hasLocation W20353388362 @default.
• W2035338836 hasOpenAccess W2035338836 @default.
• W2035338836 hasPrimaryLocation W20353388361 @default.
• W2035338836 hasRelatedWork W1500099390 @default.
• W2035338836 hasRelatedWork W1971311189 @default.
• W2035338836 hasRelatedWork W1990074641 @default.
• W2035338836 hasRelatedWork W2035338836 @default.
• W2035338836 hasRelatedWork W2160014529 @default.
• W2035338836 hasRelatedWork W2330672956 @default.
• W2035338836 hasRelatedWork W2353875092 @default.
• W2035338836 hasRelatedWork W2370418574 @default.
• W2035338836 hasRelatedWork W2370691445 @default.
• W2035338836 hasRelatedWork W4379536951 @default.

• next