Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035355989> ?p ?o ?g. }
- W2035355989 endingPage "552" @default.
- W2035355989 startingPage "544" @default.
- W2035355989 abstract "The first step of host fighting against pathogens is that pattern recognition receptors recognized pathogen-associated molecular patterns. However, the specificity of recognition within the innate immune molecular of invertebrates remains largely unknown. In the present study, we investigated how invertebrate pattern recognition receptor (PRR) C-type lectins might be involved in the antimicrobial response in crustacean. Based on our previously obtained completed coding regions of EsLecA and EsLecG in Eriocheir sinensis, the recombinant EsLectin proteins were produced via prokaryotic expression system and affinity chromatography. Subsequently, both rEsLecA and rEsLecG were discovered to have wide spectrum binding activities towards microorganisms, and their microbial-binding was calcium-independent. Moreover, the binding activities of both rEsLecA and rEsLecG induced the aggregation against microbial pathogens. Both microorganism growth inhibitory activities assays and antibacterial activities assays revealed their capabilities of suppressing microorganisms growth and directly killing microorganisms respectively. Furthermore, the encapsulation assays signified that both rEsLecA and rEsLecG could stimulate the cellular encapsulation in vitro. Collectively, data presented here demonstrated the successful expression and purification of two C-type lectins proteins in the Chinese mitten crab, and their critical role in the innate immune system of an invertebrate." @default.
- W2035355989 created "2016-06-24" @default.
- W2035355989 creator A5002078440 @default.
- W2035355989 creator A5004681952 @default.
- W2035355989 creator A5013134577 @default.
- W2035355989 creator A5020581357 @default.
- W2035355989 creator A5027998959 @default.
- W2035355989 creator A5033098447 @default.
- W2035355989 creator A5038633848 @default.
- W2035355989 creator A5046387136 @default.
- W2035355989 creator A5057557957 @default.
- W2035355989 creator A5061084605 @default.
- W2035355989 date "2013-12-01" @default.
- W2035355989 modified "2023-10-17" @default.
- W2035355989 title "Two antibacterial C-type lectins from crustacean, Eriocheir sinensis, stimulated cellular encapsulation in vitro" @default.
- W2035355989 cites W1561255328 @default.
- W2035355989 cites W1562268146 @default.
- W2035355989 cites W1567731029 @default.
- W2035355989 cites W1573617710 @default.
- W2035355989 cites W1967919858 @default.
- W2035355989 cites W1972600958 @default.
- W2035355989 cites W1978537749 @default.
- W2035355989 cites W1987022984 @default.
- W2035355989 cites W1988940244 @default.
- W2035355989 cites W1991807082 @default.
- W2035355989 cites W1999629160 @default.
- W2035355989 cites W2000816615 @default.
- W2035355989 cites W2007984372 @default.
- W2035355989 cites W2010980655 @default.
- W2035355989 cites W2013946123 @default.
- W2035355989 cites W2017755126 @default.
- W2035355989 cites W2020750760 @default.
- W2035355989 cites W2032759547 @default.
- W2035355989 cites W2037281931 @default.
- W2035355989 cites W2042177179 @default.
- W2035355989 cites W2045773810 @default.
- W2035355989 cites W2053470258 @default.
- W2035355989 cites W2055800251 @default.
- W2035355989 cites W2057347293 @default.
- W2035355989 cites W2057549746 @default.
- W2035355989 cites W2059160075 @default.
- W2035355989 cites W2065349756 @default.
- W2035355989 cites W2067658972 @default.
- W2035355989 cites W2072098306 @default.
- W2035355989 cites W2086391508 @default.
- W2035355989 cites W2114737175 @default.
- W2035355989 cites W2125912444 @default.
- W2035355989 cites W2133449490 @default.
- W2035355989 cites W2139174805 @default.
- W2035355989 cites W2173015905 @default.
- W2035355989 cites W4205423537 @default.
- W2035355989 doi "https://doi.org/10.1016/j.dci.2013.07.016" @default.
- W2035355989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23911906" @default.
- W2035355989 hasPublicationYear "2013" @default.
- W2035355989 type Work @default.
- W2035355989 sameAs 2035355989 @default.
- W2035355989 citedByCount "50" @default.
- W2035355989 countsByYear W20353559892013 @default.
- W2035355989 countsByYear W20353559892014 @default.
- W2035355989 countsByYear W20353559892015 @default.
- W2035355989 countsByYear W20353559892016 @default.
- W2035355989 countsByYear W20353559892017 @default.
- W2035355989 countsByYear W20353559892018 @default.
- W2035355989 countsByYear W20353559892019 @default.
- W2035355989 countsByYear W20353559892020 @default.
- W2035355989 countsByYear W20353559892021 @default.
- W2035355989 countsByYear W20353559892022 @default.
- W2035355989 countsByYear W20353559892023 @default.
- W2035355989 crossrefType "journal-article" @default.
- W2035355989 hasAuthorship W2035355989A5002078440 @default.
- W2035355989 hasAuthorship W2035355989A5004681952 @default.
- W2035355989 hasAuthorship W2035355989A5013134577 @default.
- W2035355989 hasAuthorship W2035355989A5020581357 @default.
- W2035355989 hasAuthorship W2035355989A5027998959 @default.
- W2035355989 hasAuthorship W2035355989A5033098447 @default.
- W2035355989 hasAuthorship W2035355989A5038633848 @default.
- W2035355989 hasAuthorship W2035355989A5046387136 @default.
- W2035355989 hasAuthorship W2035355989A5057557957 @default.
- W2035355989 hasAuthorship W2035355989A5061084605 @default.
- W2035355989 hasConcept C104317684 @default.
- W2035355989 hasConcept C106257327 @default.
- W2035355989 hasConcept C111289621 @default.
- W2035355989 hasConcept C136449434 @default.
- W2035355989 hasConcept C170493617 @default.
- W2035355989 hasConcept C202751555 @default.
- W2035355989 hasConcept C203014093 @default.
- W2035355989 hasConcept C2776460866 @default.
- W2035355989 hasConcept C2778914303 @default.
- W2035355989 hasConcept C40767141 @default.
- W2035355989 hasConcept C4937899 @default.
- W2035355989 hasConcept C55493867 @default.
- W2035355989 hasConcept C86803240 @default.
- W2035355989 hasConcept C8891405 @default.
- W2035355989 hasConcept C89423630 @default.
- W2035355989 hasConcept C90856448 @default.
- W2035355989 hasConceptScore W2035355989C104317684 @default.
- W2035355989 hasConceptScore W2035355989C106257327 @default.
- W2035355989 hasConceptScore W2035355989C111289621 @default.