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• W2035367018 endingPage "421" @default.
• W2035367018 startingPage "407" @default.
• W2035367018 abstract "Major hepatic resection is now performed frequently and with relative safety, but is accompanied by significant pathophysiological changes. The aim of this review is to describe these changes along with interventions that may help reduce the risk for adverse outcomes after major hepatic resection.The MEDLINE, EMBASE and CENTRAL databases were searched for relevant literature published from January 2000 to December 2011. Broad subject headings were 'hepatectomy/', 'liver function/', 'liver failure/' and 'physiology/'.Predictable changes in blood biochemistry and coagulation occur following major hepatic resection and alterations from the expected path indicate a complicated course. Susceptibility to sepsis, functional renal impairment, and altered energy metabolism are important sequelae of post-resection liver failure.The pathophysiology of post-resection liver failure is difficult to reverse and thus strategies aimed at prevention are key to reducing morbidity and mortality after liver surgery." @default.
• W2035367018 created "2016-06-24" @default.
• W2035367018 creator A5013938734 @default.
• W2035367018 creator A5072892514 @default.
• W2035367018 creator A5089879428 @default.
• W2035367018 date "2014-05-01" @default.
• W2035367018 modified "2023-10-16" @default.
• W2035367018 title "Systematic review of pathophysiological changes following hepatic resection" @default.
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