Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035381441> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2035381441 endingPage "546" @default.
- W2035381441 startingPage "542" @default.
- W2035381441 abstract "This article introduces a new method of component preparation that is capable of producing white cell (WBC)-reduced platelet concentrates (PCs) from whole blood. Whole blood is separated into packed red cells (RBCs) and platelet-rich plasma (PRP) by centrifugation, and the PRP is expressed through a newly designed WBC removal filter into the platelet storage bag. The filtered PRP is then centrifuged and yields WBC- reduced PCs and plasma for freezing as fresh-frozen plasma (FFP). The method uses standard triple-pack blood bags and centrifugation protocols. Fifteen WBC-reduced PCs prepared with this technique had an average volume of 56.7 mL, an average Day 5 platelet content of 8.6 × 10(10) per unit, and an average Day 5 WBC content of 0.83 +/− 0.7 × 10(4) per unit (0.14 WBCs/microL). This represents WBC removal equal to at least 99.9 percent (3 log10) of the WBCs found in standard PCs prepared in our laboratory by an identical centrifugation protocol. Paired studies documented a 4.5-percent platelet loss by filtration. Filtration had no effect on the plasma prepared for FFP as measured by prothrombin time; activated partial thromboplastin time; factors I, V, VIII:C, and VIII:von Willebrand factor; antithrombin-III; albumin; globulin; or total protein. This method holds promise as a simple and highly effective technique for the production of WBC-reduced PCs by filtration during component preparation." @default.
- W2035381441 created "2016-06-24" @default.
- W2035381441 creator A5017747750 @default.
- W2035381441 creator A5052649512 @default.
- W2035381441 creator A5084259941 @default.
- W2035381441 date "1991-07-01" @default.
- W2035381441 modified "2023-09-25" @default.
- W2035381441 title "Preparation of white cell-reduced platelet concentrates from whole blood during component preparation" @default.
- W2035381441 doi "https://doi.org/10.1046/j.1537-2995.1991.31691306254.x" @default.
- W2035381441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1853450" @default.
- W2035381441 hasPublicationYear "1991" @default.
- W2035381441 type Work @default.
- W2035381441 sameAs 2035381441 @default.
- W2035381441 citedByCount "15" @default.
- W2035381441 countsByYear W20353814412013 @default.
- W2035381441 countsByYear W20353814412015 @default.
- W2035381441 crossrefType "journal-article" @default.
- W2035381441 hasAuthorship W2035381441A5017747750 @default.
- W2035381441 hasAuthorship W2035381441A5052649512 @default.
- W2035381441 hasAuthorship W2035381441A5084259941 @default.
- W2035381441 hasConcept C105795698 @default.
- W2035381441 hasConcept C128489963 @default.
- W2035381441 hasConcept C1621761 @default.
- W2035381441 hasConcept C185592680 @default.
- W2035381441 hasConcept C203014093 @default.
- W2035381441 hasConcept C2776125364 @default.
- W2035381441 hasConcept C2778261982 @default.
- W2035381441 hasConcept C2778488018 @default.
- W2035381441 hasConcept C2780076745 @default.
- W2035381441 hasConcept C33923547 @default.
- W2035381441 hasConcept C43617362 @default.
- W2035381441 hasConcept C55493867 @default.
- W2035381441 hasConcept C71924100 @default.
- W2035381441 hasConcept C7623868 @default.
- W2035381441 hasConcept C89560881 @default.
- W2035381441 hasConceptScore W2035381441C105795698 @default.
- W2035381441 hasConceptScore W2035381441C128489963 @default.
- W2035381441 hasConceptScore W2035381441C1621761 @default.
- W2035381441 hasConceptScore W2035381441C185592680 @default.
- W2035381441 hasConceptScore W2035381441C203014093 @default.
- W2035381441 hasConceptScore W2035381441C2776125364 @default.
- W2035381441 hasConceptScore W2035381441C2778261982 @default.
- W2035381441 hasConceptScore W2035381441C2778488018 @default.
- W2035381441 hasConceptScore W2035381441C2780076745 @default.
- W2035381441 hasConceptScore W2035381441C33923547 @default.
- W2035381441 hasConceptScore W2035381441C43617362 @default.
- W2035381441 hasConceptScore W2035381441C55493867 @default.
- W2035381441 hasConceptScore W2035381441C71924100 @default.
- W2035381441 hasConceptScore W2035381441C7623868 @default.
- W2035381441 hasConceptScore W2035381441C89560881 @default.
- W2035381441 hasIssue "6" @default.
- W2035381441 hasLocation W20353814411 @default.
- W2035381441 hasLocation W20353814412 @default.
- W2035381441 hasOpenAccess W2035381441 @default.
- W2035381441 hasPrimaryLocation W20353814411 @default.
- W2035381441 hasRelatedWork W172326098 @default.
- W2035381441 hasRelatedWork W1992900668 @default.
- W2035381441 hasRelatedWork W2035381441 @default.
- W2035381441 hasRelatedWork W2073542861 @default.
- W2035381441 hasRelatedWork W2123341631 @default.
- W2035381441 hasRelatedWork W2147887171 @default.
- W2035381441 hasRelatedWork W2657164153 @default.
- W2035381441 hasRelatedWork W2765298077 @default.
- W2035381441 hasRelatedWork W2940939964 @default.
- W2035381441 hasRelatedWork W3163783667 @default.
- W2035381441 hasVolume "31" @default.
- W2035381441 isParatext "false" @default.
- W2035381441 isRetracted "false" @default.
- W2035381441 magId "2035381441" @default.
- W2035381441 workType "article" @default.