FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035388743> ?p ?o ?g. }

• W2035388743 endingPage "219" @default.
• W2035388743 startingPage "207" @default.
• W2035388743 abstract "In prokaryotes, unicellular eukaryotes and cell-free systems, pressure is known to exert an inhibitory effect on protein synthesis and RNA metabolism, the mechanism(s) of which remain to be investigated in detail. The purpose of the present in vitro study was to compare ultrastructural and quantitative changes of the nucleolus, which is the site of ribosome biogenesis, in sympathetic neurons of rat superior cervical ganglia (SCG) maintained for 2, 3 and 5 h in NCTC 109 medium and subjected to pressure or not. In control SCG (left) the nucleolus greatly increased in volume (+ 33%) 2 h after excision, in comparison with SCG fixed immediately. This overall enlargement was found to reflect a marked increase in all nucleolar components (from 16 to 87%). After 5 h, volumes of nucleolus, fibrillar centers and vacuolar component returned to control values, whereas dense fibrillar and granular components remained affected. Such early and transient changes are regarded as reflecting basic metabolic changes associated with increased nucleolar RNA that should be of primary concern to experiments using SCG transplanted in culture media. Compression under helium up to 180 atmospheric pressure for 1 h of right SCG maintained for 2 h in culture medium, was shown to induce, on the contrary, a marked decrease in nucleolar volume (-39%) and in volumes of all nucleolar components (from -36 to -51%). When they were kept at constant high pressure for 1 and 3 h a progressive recovery of volumes of nucleoli and nucleolar components was observed. Consequently, compression was shown to exert opposite effects to those of isolation of SCG. Present data are interpreted as an inhibitory effect of pressure on ribosome biogenesis. Such observations on a vertebrate neuron might open a new field in the search for cellular mechanisms underlying the effects of pressure on living organisms and especially on the nervous system." @default.
• W2035388743 created "2016-06-24" @default.
• W2035388743 creator A5021676270 @default.
• W2035388743 creator A5059644873 @default.
• W2035388743 creator A5074298045 @default.
• W2035388743 creator A5086112951 @default.
• W2035388743 date "1989-08-01" @default.
• W2035388743 modified "2023-09-27" @default.
• W2035388743 title "Effects of isolation and high helium pressure on the nucleolus of sympathetic neurons in the rat superior cervical ganglion" @default.
• W2035388743 cites W142080826 @default.
• W2035388743 cites W1530179459 @default.
• W2035388743 cites W1590028580 @default.
• W2035388743 cites W1681431349 @default.
• W2035388743 cites W1828940131 @default.
• W2035388743 cites W1833444970 @default.
• W2035388743 cites W1899366565 @default.
• W2035388743 cites W1905023859 @default.
• W2035388743 cites W1917711091 @default.
• W2035388743 cites W1936741604 @default.
• W2035388743 cites W1963961621 @default.
• W2035388743 cites W1969005705 @default.
• W2035388743 cites W1969868065 @default.
• W2035388743 cites W1972818076 @default.
• W2035388743 cites W1979357644 @default.
• W2035388743 cites W1979968146 @default.
• W2035388743 cites W1980357299 @default.
• W2035388743 cites W1986080532 @default.
• W2035388743 cites W1986282708 @default.
• W2035388743 cites W1988666686 @default.
• W2035388743 cites W1993226505 @default.
• W2035388743 cites W1993687544 @default.
• W2035388743 cites W1996468935 @default.
• W2035388743 cites W1997128617 @default.
• W2035388743 cites W1999294647 @default.
• W2035388743 cites W2001328290 @default.
• W2035388743 cites W2006646132 @default.
• W2035388743 cites W2009090460 @default.
• W2035388743 cites W2011607916 @default.
• W2035388743 cites W2026373882 @default.
• W2035388743 cites W2027799259 @default.
• W2035388743 cites W2027958460 @default.
• W2035388743 cites W2029827190 @default.
• W2035388743 cites W2035606742 @default.
• W2035388743 cites W2035800203 @default.
• W2035388743 cites W2041821408 @default.
• W2035388743 cites W2048712735 @default.
• W2035388743 cites W2050264670 @default.
• W2035388743 cites W2052774820 @default.
• W2035388743 cites W2056199339 @default.
• W2035388743 cites W2061169713 @default.
• W2035388743 cites W2062386983 @default.
• W2035388743 cites W2066171525 @default.
• W2035388743 cites W2068922136 @default.
• W2035388743 cites W2069756751 @default.
• W2035388743 cites W2070495808 @default.
• W2035388743 cites W2071324268 @default.
• W2035388743 cites W2072073761 @default.
• W2035388743 cites W2072280876 @default.
• W2035388743 cites W2075442711 @default.
• W2035388743 cites W2080259621 @default.
• W2035388743 cites W2081276300 @default.
• W2035388743 cites W2084304425 @default.
• W2035388743 cites W2085735820 @default.
• W2035388743 cites W2086064327 @default.
• W2035388743 cites W2086462942 @default.
• W2035388743 cites W2087267466 @default.
• W2035388743 cites W2092576513 @default.
• W2035388743 cites W2120579416 @default.
• W2035388743 cites W2126658821 @default.
• W2035388743 cites W2135289419 @default.
• W2035388743 cites W2164745770 @default.
• W2035388743 cites W2306365244 @default.
• W2035388743 cites W2327372768 @default.
• W2035388743 cites W2344261471 @default.
• W2035388743 cites W4211087645 @default.
• W2035388743 doi "https://doi.org/10.1016/0165-1838(89)90114-8" @default.
• W2035388743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2794347" @default.
• W2035388743 hasPublicationYear "1989" @default.
• W2035388743 type Work @default.
• W2035388743 sameAs 2035388743 @default.
• W2035388743 citedByCount "4" @default.
• W2035388743 countsByYear W20353887432020 @default.
• W2035388743 crossrefType "journal-article" @default.
• W2035388743 hasAuthorship W2035388743A5021676270 @default.
• W2035388743 hasAuthorship W2035388743A5059644873 @default.
• W2035388743 hasAuthorship W2035388743A5074298045 @default.
• W2035388743 hasAuthorship W2035388743A5086112951 @default.
• W2035388743 hasConcept C104317684 @default.
• W2035388743 hasConcept C105702510 @default.
• W2035388743 hasConcept C183873130 @default.
• W2035388743 hasConcept C185592680 @default.
• W2035388743 hasConcept C2778993773 @default.
• W2035388743 hasConcept C2780723820 @default.
• W2035388743 hasConcept C54355233 @default.
• W2035388743 hasConcept C67705224 @default.
• W2035388743 hasConcept C86803240 @default.
• W2035388743 hasConcept C88478588 @default.
• W2035388743 hasConcept C95444343 @default.

• next