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• W2035400146 endingPage "1577" @default.
• W2035400146 startingPage "1513" @default.
• W2035400146 abstract "The applications of computers to biological and biomedical problem solving go back to the very beginnings of computer science, automata theory [1], and mathematical biology [2]. With the advent of more versatile and powerful computers, biological and biomedical applications of computers have proliferated so rapidly that it would be virtually impossible to compile a comprehensive review of all developments in this field. Limitations of computer simulations in biology have also come under close scrutiny, and claims have been made that biological systems have limited information processing power [3]. Such general conjectures do not, however, deter biologists and biomedical researchers from developing new computer applications in biology and medicine. Microprocessors are being widely employed in biological laboratories both for automatic data acquisition/processing and modeling; one particular area, which is of great biomedical interest, involves fast digital image processing and is already established for routine clinical examinations in radiological and nuclear medicine centers, Powerful techniques for biological research are routinely employing dedicated, on-line microprocessors or array processors; among such techniques are: Fourier-transform nuclear magnetic resonance (NMR), NMR imaging (or tomography), x-ray tomography, x-ray diffraction, high performance liquid chromatography, differential scanning calorimetry and mass spectrometry. Networking of laboratory microprocessors linked to a central, large memory computer is the next logical step in laboratory automation. Previously unapproachable problems, such as molecular dynamics of solutions, many-body interaction calculations and statistical mechanics of biological processes are all likely to benefit from the increasing access to the new generation of supercomputers. In view of the large number, diversity and complexity of computer applications in biology and medicine, we could not review in any degree of detail all computer applications in these fields; instead, we shall be selective and focus our discussion on suggestive computer models of biological systems and those fundamental aspects of computer applications that are likely to continue to make an impact on biological and biomedical research. Thus, we shall consider unifying trends in mathematics, mathematical logics and computer science that are relevant to computer modeling of biological and biomedical systems. The latter are pitched at a more formal, abstract level than the applications and, therefore, encompass a number of concepts drawn from the abstract theory of sets and relations, network theory, automata theory, Boolean and n-valued logics, abstract algebra, topology and category theory. The present analysis of relational theories in biology and computer simulation has also inspired a number of new results which are presented here as Conjectures since their proofs are too lengthy and too technical to be included in this review. In order to maintain a self-contained presentation-the definitions of the main concepts are given, with the exception of a minimum of simple mathematical concepts. The purpose of these theoretical sections is to provide the basis for approaching a number of basic biological questions: (1) What are the essential characteristics of a biological organism as opposed to an automaton? (2) Are biological systems recursively computable? (3) What is the structure of the simplest (primordial) organism? (4) What are the basic structures of neural and genetic networks? (5) What are the common properties of classes of biological organisms? (6) Which system representations are adequate for biodynamics? (7) What is the optimal strategy for modifying an organism through genetic engineering? (8) What is the optimal simulation of a biological system with a digital or analog computer? (9) What is life?" @default.
• W2035400146 created "2016-06-24" @default.
• W2035400146 creator A5044662649 @default.
• W2035400146 date "1986-01-01" @default.
• W2035400146 modified "2023-09-30" @default.
• W2035400146 title "Computer models and automata theory in biology and medicine" @default.
• W2035400146 cites W114269992 @default.
• W2035400146 cites W1536895451 @default.
• W2035400146 cites W1544532551 @default.
• W2035400146 cites W1572103923 @default.
• W2035400146 cites W1579485993 @default.
• W2035400146 cites W1581140154 @default.
• W2035400146 cites W1603574803 @default.
• W2035400146 cites W160380472 @default.
• W2035400146 cites W174538223 @default.
• W2035400146 cites W176118634 @default.
• W2035400146 cites W1791560065 @default.
• W2035400146 cites W180282559 @default.
• W2035400146 cites W1810229463 @default.
• W2035400146 cites W1860574495 @default.
• W2035400146 cites W1949993382 @default.
• W2035400146 cites W1963716182 @default.
• W2035400146 cites W1963897690 @default.
• W2035400146 cites W1964465385 @default.
• W2035400146 cites W1964756562 @default.
• W2035400146 cites W1965006842 @default.
• W2035400146 cites W1965257311 @default.
• W2035400146 cites W1965809799 @default.
• W2035400146 cites W1966658420 @default.
• W2035400146 cites W1966884120 @default.
• W2035400146 cites W1967371633 @default.
• W2035400146 cites W1968377491 @default.
• W2035400146 cites W1968532364 @default.
• W2035400146 cites W1968738109 @default.
• W2035400146 cites W1968767630 @default.
• W2035400146 cites W1969179797 @default.
• W2035400146 cites W1969547738 @default.
• W2035400146 cites W1971089744 @default.
• W2035400146 cites W1971224531 @default.
• W2035400146 cites W1971475769 @default.
• W2035400146 cites W1972663764 @default.
• W2035400146 cites W1972983982 @default.
• W2035400146 cites W1973294680 @default.
• W2035400146 cites W1974879918 @default.
• W2035400146 cites W1975519085 @default.
• W2035400146 cites W1976345925 @default.
• W2035400146 cites W1976506081 @default.
• W2035400146 cites W1976706540 @default.
• W2035400146 cites W1978741752 @default.
• W2035400146 cites W1979694525 @default.
• W2035400146 cites W1979704006 @default.
• W2035400146 cites W1979971526 @default.
• W2035400146 cites W1980198741 @default.
• W2035400146 cites W1980930111 @default.
• W2035400146 cites W1981015833 @default.
• W2035400146 cites W1985556515 @default.
• W2035400146 cites W1985940938 @default.
• W2035400146 cites W1986536556 @default.
• W2035400146 cites W1991593435 @default.
• W2035400146 cites W1992015804 @default.
• W2035400146 cites W1993744672 @default.
• W2035400146 cites W1994659438 @default.
• W2035400146 cites W1994813980 @default.
• W2035400146 cites W1995030605 @default.
• W2035400146 cites W1995341919 @default.
• W2035400146 cites W1996354253 @default.
• W2035400146 cites W1996454832 @default.
• W2035400146 cites W1996567184 @default.
• W2035400146 cites W1998978018 @default.
• W2035400146 cites W1999486339 @default.
• W2035400146 cites W2000063811 @default.
• W2035400146 cites W2001554557 @default.
• W2035400146 cites W2005492971 @default.
• W2035400146 cites W2005959911 @default.
• W2035400146 cites W2006480085 @default.
• W2035400146 cites W2008246012 @default.
• W2035400146 cites W2010292207 @default.
• W2035400146 cites W2010691237 @default.
• W2035400146 cites W2010918860 @default.
• W2035400146 cites W2011624313 @default.
• W2035400146 cites W2013260039 @default.
• W2035400146 cites W2013777381 @default.
• W2035400146 cites W2015887064 @default.
• W2035400146 cites W2016354087 @default.
• W2035400146 cites W2017691475 @default.
• W2035400146 cites W2017694668 @default.
• W2035400146 cites W2019863929 @default.
• W2035400146 cites W2020073162 @default.
• W2035400146 cites W2021149998 @default.
• W2035400146 cites W2022348461 @default.
• W2035400146 cites W2022601249 @default.
• W2035400146 cites W2022714214 @default.
• W2035400146 cites W2024426967 @default.
• W2035400146 cites W2024476127 @default.
• W2035400146 cites W2024551450 @default.
• W2035400146 cites W2025322374 @default.
• W2035400146 cites W2026427953 @default.
• W2035400146 cites W2029788969 @default.

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