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• W2035429823 endingPage "5540" @default.
• W2035429823 startingPage "5540" @default.
• W2035429823 abstract "Crohn's disease is a chronic inflammatory condition that may involve any segment of the gastrointestinal tract. Although several drugs have proven efficacy in inducing and maintaining disease in remission, resectional surgery remains as a cornerstone in the management of the disease, mainly for the treatment of its stenosing and penetrating complications. However, the occurrence of new mucosal (endoscopic) lesions in the neoterminal ileum early after surgery is almost constant, it is followed in the mid-term by clinical symptoms and, in a proportion of patients, repeated intestinal resections are required. Pathogenesis of postoperative recurrence (POR) is not fully understood, but luminal factors (commensal microbes, dietary antigens) seem to play an important role, and environmental and genetic factors may also have a relevant influence. Many studies tried to identify clinical predictors for POR with heterogeneous results, and only smoking has repeatedly been associated with a higher risk of POR. Ileocolonoscopy remains as the gold standard for the assessment of appearance and severity of POR, although the real usefulness of the available endoscopic score needs to be revisited and alternative techniques are emerging. Several drugs have been evaluated to prevent POR with limited success. Smoking cessation seems to be one of the more beneficial therapeutic measures. Aminosalicylates have only proved to be of marginal benefit, and they are only used in low-risk patients. Nitroimidazolic antibiotics, although efficient, are associated with a high rate of intolerance and might induce irreversible side effects when used for a long-term. Thiopurines are not widely used after ileocecal resection, maybe because some concerns in giving immunomodulators in asymptomatic patients still remain. In the era of biological agents and genetic testing, a well-established preventive strategy for POR is still lacking, and larger studies to identify good clinical, serological, and genetic predictors of early POR as well as more effective drugs (or drug combinations) are needed." @default.
• W2035429823 created "2016-06-24" @default.
• W2035429823 creator A5064167457 @default.
• W2035429823 creator A5082466185 @default.
• W2035429823 date "2008-01-01" @default.
• W2035429823 modified "2023-10-18" @default.
• W2035429823 title "Postoperative Crohn’s disease recurrence: A practical approach" @default.
• W2035429823 cites W144551636 @default.
• W2035429823 cites W1522944862 @default.
• W2035429823 cites W1547383859 @default.
• W2035429823 cites W1574038957 @default.
• W2035429823 cites W1598305109 @default.
• W2035429823 cites W1752248076 @default.
• W2035429823 cites W1902595583 @default.
• W2035429823 cites W1932727195 @default.
• W2035429823 cites W1952529329 @default.
• W2035429823 cites W1967136803 @default.
• W2035429823 cites W1967651790 @default.
• W2035429823 cites W1969354506 @default.
• W2035429823 cites W1969879447 @default.
• W2035429823 cites W1969959904 @default.
• W2035429823 cites W1970579300 @default.
• W2035429823 cites W1970650064 @default.
• W2035429823 cites W1976789706 @default.
• W2035429823 cites W1979236956 @default.
• W2035429823 cites W1980212383 @default.
• W2035429823 cites W1981575166 @default.
• W2035429823 cites W1987027320 @default.
• W2035429823 cites W1989883376 @default.
• W2035429823 cites W1997702183 @default.
• W2035429823 cites W2000915117 @default.
• W2035429823 cites W2001113033 @default.
• W2035429823 cites W2001678644 @default.
• W2035429823 cites W2001718357 @default.
• W2035429823 cites W2009678756 @default.
• W2035429823 cites W2012812407 @default.
• W2035429823 cites W2014229988 @default.
• W2035429823 cites W2014761323 @default.
• W2035429823 cites W2016703827 @default.
• W2035429823 cites W2018603454 @default.
• W2035429823 cites W2020119586 @default.
• W2035429823 cites W2023957341 @default.
• W2035429823 cites W2024297964 @default.
• W2035429823 cites W2027983594 @default.
• W2035429823 cites W2033973171 @default.
• W2035429823 cites W2035088777 @default.
• W2035429823 cites W2040044115 @default.
• W2035429823 cites W2045836948 @default.
• W2035429823 cites W2051898907 @default.
• W2035429823 cites W2052496052 @default.
• W2035429823 cites W2059691196 @default.
• W2035429823 cites W2060943167 @default.
• W2035429823 cites W2062369130 @default.
• W2035429823 cites W2064894211 @default.
• W2035429823 cites W2065277970 @default.
• W2035429823 cites W2067337470 @default.
• W2035429823 cites W2068376497 @default.
• W2035429823 cites W2081754558 @default.
• W2035429823 cites W2082293961 @default.
• W2035429823 cites W2082918690 @default.
• W2035429823 cites W2087318495 @default.
• W2035429823 cites W2089204801 @default.
• W2035429823 cites W2090549398 @default.
• W2035429823 cites W2096308931 @default.
• W2035429823 cites W2109460962 @default.
• W2035429823 cites W2111446303 @default.
• W2035429823 cites W2114214481 @default.
• W2035429823 cites W2114473465 @default.
• W2035429823 cites W2118161476 @default.
• W2035429823 cites W2118688515 @default.
• W2035429823 cites W2130153850 @default.
• W2035429823 cites W2135433890 @default.
• W2035429823 cites W2137775651 @default.
• W2035429823 cites W2140741976 @default.
• W2035429823 cites W2147324797 @default.
• W2035429823 cites W2147917065 @default.
• W2035429823 cites W2148859286 @default.
• W2035429823 cites W2149531426 @default.
• W2035429823 cites W2152381563 @default.
• W2035429823 cites W2153160957 @default.
• W2035429823 cites W2166479393 @default.
• W2035429823 cites W2171341132 @default.
• W2035429823 cites W227766145 @default.
• W2035429823 cites W25493465 @default.
• W2035429823 cites W4241611245 @default.
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• W2035429823 doi "https://doi.org/10.3748/wjg.14.5540" @default.
• W2035429823 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2746342" @default.
• W2035429823 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18810773" @default.
• W2035429823 hasPublicationYear "2008" @default.
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