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• W2035436929 abstract "The present investigation is aimed at characterizing the development of ON and OFF visually evoked responses in the rat superior colliculus from postnatal day 13 (P13) to postnatal day 25. Depth profiles of field potentials reveal that ON and OFF long latency biphasic field potentials are already present when collicular cells are first responsive to light (P13). There is an inversion in the polarity of these reponses as the electrode penetrates the collicular layers, suggesting a synaptic organization similar to the one found in adult animals. At P15, OFF field potentials begin to exhibit oscillatory activity. Local cobalt injections within the superior colliculus abolishes these OFF oscillations, suggesting a postsynaptic origin. Fast Fourier transform (FFT) analysis of the OFF field potentials demonstrates that oscillatory activity increases in frequency during development. This increase is thought to reflect the myelination and stabilization of synaptic connections that occur during this period. To our knowledge, this is the first report of OFF oscillatory responses in the superior collliculus." @default.
• W2035436929 created "2016-06-24" @default.
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• W2035436929 date "1997-11-01" @default.
• W2035436929 modified "2023-10-03" @default.
• W2035436929 title "ON and OFF field potentials in the rat superior colliculus during development" @default.
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• W2035436929 doi "https://doi.org/10.1016/s0042-6989(97)00145-4" @default.
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