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• W2035458333 abstract "AMPA receptors (AMPARs) are an important therapeutic target in the CNS. A series of substituted benzoxazinone derivatives with good to very good in vitro activity as positive allosteric AMPAR modulators was synthesized and evaluated. The appropriate substituent choice on the benzoxazinone fragment improved the affinity towards the AMPA receptor significantly in comparison to our lead molecule CX614." @default.
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• W2035458333 date "2011-07-01" @default.
• W2035458333 modified "2023-10-16" @default.
• W2035458333 title "Substituted benzoxazinones as potent positive allosteric AMPA receptor modulators: Part II" @default.
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• W2035458333 doi "https://doi.org/10.1016/j.bmcl.2011.05.024" @default.
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