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- W2035484420 abstract "The role of Helicobacter pylori as a determinant of cardiovascular disease is controversial.To determine whether previous exposure to H. pylori is associated with an increased risk for myocardial infarction.Prospective case-control study.Physicians' Health Study.Initially healthy U.S. men.Titers of IgG antibody against H. pylori and several inflammatory markers were measured in baseline blood samples obtained from 445 men who subsequently had a myocardial infarction (case-patients) and 445 men matched for age and smoking status who remained free of vascular disease (controls) during a mean follow-up of 8.9 years.Baseline seropositivity was similar among case-patients and controls (43.4% vs. 44.3%; rate ratio, 0.96 [95% CI, 0.7 to 1.3]). Minimal evidence of association was found between magnitude of seropositivity and subsequent risk and between seropositivity and levels of the inflammatory biomarkers.In a socioeconomically homogeneous population, we found limited evidence of association between H. pylori exposure and risk for future myocardial infarction." @default.
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- W2035484420 date "2001-08-07" @default.
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- W2035484420 title "A Prospective Study of <i>Helicobacter pylori</i> Seropositivity and the Risk for Future Myocardial Infarction among Socioeconomically Similar U.S. Men" @default.
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- W2035484420 doi "https://doi.org/10.7326/0003-4819-135-3-200108070-00010" @default.
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