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• W2035521803 abstract "Summary. We report on a man suffering from chronic myelogenous leukaemia treated by allogeneic bone marrow transplantation who, in the late post‐transplantation phase, developed a hyperacute fatal invasive rhinocerebral zygomycosis. The origin of the ascending infection was the sinus sphenoidalis from which fungal hyphae spread to the central nervous system via the skull and the dura mater. The first symptoms of this severe infection were cerebral convulsions and a bilateral total amaurosis. The isolation of the pathogen from post mortem tisue was not successful. The present case is compared with previous reports of zygomycoses after bone marrow transplantation. Zusammenfassung. Ein Mann mit chronisch myeloischer Leukämie wurde knochenmarktransplantiert und entwickelte in der späten Posttransplantationsphase eine hyperakute, fatale invasive rhinozerebrale Zygomykose. Der Ursprung der aufsteigenden Infektion war der Sinus sphenoidalis, von dem aus sich Pilzhyphen über die Schädelbasis und die Dura mater in das Zentralnervensystem ausbreiteten. Erstsymptome dieser schweren Infektion waren zerebrale Krampfanfälle und eine bilaterale Amaurose. Die kulturelle Isolierung des Erregers aus Autopsiematerial gelang nicht. Der vorliegende Fall wird mit anderen Kasuistiken von Zygomykosen nach Knochenmarktransplantation verglichen." @default.
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• W2035521803 date "1998-11-01" @default.
• W2035521803 modified "2023-09-23" @default.
• W2035521803 title "Rhinocerebral zygomycosis following bone marrow transplantation in chronic myelogenous leukaemia. Report of a case and review of the literature" @default.
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• W2035521803 doi "https://doi.org/10.1111/j.1439-0507.1998.tb00355.x" @default.
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