FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035543265> ?p ?o ?g. }

• W2035543265 endingPage "597" @default.
• W2035543265 startingPage "593" @default.
• W2035543265 abstract "Poly(hydroxybutyrate-co-hydroxyhexanoate) (PHBHHx), a member of the polyhydroxyalkanoate family of biopolyesters, has superior mechanical properties and biocompatibilities that enable it to meet diverse biomedical requirements. The main component of PHBHHx is dl-β-hydroxybutyric acid (HB), a ketone body that is also produced in vivo. The effects of HB treatment on murine fibroblast L929 cells, human umbilical vein endothelial cells, and rabbit articular cartilages were investigated. HB (0.005−0.10 g/L) promoted cell proliferation for each cell line. Cell cycle analysis indicated that HB had a stimulatory effect on DNA synthesis. Flow cytometric analysis of L929 cells revealed changes in the [Ca2+]i for different stages of the cell cycle. In L929 cells, HB (0.02 g/L) stimulated a rapid increase in the concentration of cytosolic calcium that was blocked by verapamil and diltiazem, inhibitors of L-type Ca2+ channels. Finally, verapamil inhibited HB-induced L929 cell proliferation. Collectively, these results indicated that HB had a stimulatory effect on cell cycle progression that is mediated by a signaling pathway dependent upon increases in [Ca2+]i. This trophic effect may underlie the good biocompatibility observed for PHBHHx." @default.
• W2035543265 created "2016-06-24" @default.
• W2035543265 creator A5017175637 @default.
• W2035543265 creator A5019221209 @default.
• W2035543265 creator A5025762098 @default.
• W2035543265 creator A5037295695 @default.
• W2035543265 creator A5037736282 @default.
• W2035543265 creator A5077938864 @default.
• W2035543265 date "2004-12-30" @default.
• W2035543265 modified "2023-09-27" @default.
• W2035543265 title "Influence of <scp>dl</scp>-β-Hydroxybutyric Acid on Cell Proliferation and Calcium Influx" @default.
• W2035543265 cites W1553235593 @default.
• W2035543265 cites W1971854467 @default.
• W2035543265 cites W1977186296 @default.
• W2035543265 cites W1977874950 @default.
• W2035543265 cites W1979724113 @default.
• W2035543265 cites W2002883826 @default.
• W2035543265 cites W2012798322 @default.
• W2035543265 cites W2015575124 @default.
• W2035543265 cites W2017276641 @default.
• W2035543265 cites W2030340093 @default.
• W2035543265 cites W2032842753 @default.
• W2035543265 cites W2048493287 @default.
• W2035543265 cites W2060494531 @default.
• W2035543265 cites W2065398804 @default.
• W2035543265 cites W2065945848 @default.
• W2035543265 cites W2081113123 @default.
• W2035543265 cites W2081136116 @default.
• W2035543265 cites W2087444227 @default.
• W2035543265 cites W2092499238 @default.
• W2035543265 cites W2114445980 @default.
• W2035543265 cites W2144744614 @default.
• W2035543265 cites W2152152697 @default.
• W2035543265 cites W2153436542 @default.
• W2035543265 cites W2157813625 @default.
• W2035543265 cites W2414941468 @default.
• W2035543265 cites W4242174061 @default.
• W2035543265 doi "https://doi.org/10.1021/bm049465y" @default.
• W2035543265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15762618" @default.
• W2035543265 hasPublicationYear "2004" @default.
• W2035543265 type Work @default.
• W2035543265 sameAs 2035543265 @default.
• W2035543265 citedByCount "55" @default.
• W2035543265 countsByYear W20355432652012 @default.
• W2035543265 countsByYear W20355432652013 @default.
• W2035543265 countsByYear W20355432652014 @default.
• W2035543265 countsByYear W20355432652015 @default.
• W2035543265 countsByYear W20355432652016 @default.
• W2035543265 countsByYear W20355432652017 @default.
• W2035543265 countsByYear W20355432652018 @default.
• W2035543265 countsByYear W20355432652019 @default.
• W2035543265 countsByYear W20355432652020 @default.
• W2035543265 countsByYear W20355432652021 @default.
• W2035543265 countsByYear W20355432652022 @default.
• W2035543265 countsByYear W20355432652023 @default.
• W2035543265 crossrefType "journal-article" @default.
• W2035543265 hasAuthorship W2035543265A5017175637 @default.
• W2035543265 hasAuthorship W2035543265A5019221209 @default.
• W2035543265 hasAuthorship W2035543265A5025762098 @default.
• W2035543265 hasAuthorship W2035543265A5037295695 @default.
• W2035543265 hasAuthorship W2035543265A5037736282 @default.
• W2035543265 hasAuthorship W2035543265A5077938864 @default.
• W2035543265 hasConcept C1491633281 @default.
• W2035543265 hasConcept C178790620 @default.
• W2035543265 hasConcept C185592680 @default.
• W2035543265 hasConcept C202751555 @default.
• W2035543265 hasConcept C2777022698 @default.
• W2035543265 hasConcept C2777411675 @default.
• W2035543265 hasConcept C29537977 @default.
• W2035543265 hasConcept C519063684 @default.
• W2035543265 hasConcept C523546767 @default.
• W2035543265 hasConcept C54355233 @default.
• W2035543265 hasConcept C55493867 @default.
• W2035543265 hasConcept C62112901 @default.
• W2035543265 hasConcept C73447357 @default.
• W2035543265 hasConcept C81885089 @default.
• W2035543265 hasConcept C86803240 @default.
• W2035543265 hasConcept C95444343 @default.
• W2035543265 hasConceptScore W2035543265C1491633281 @default.
• W2035543265 hasConceptScore W2035543265C178790620 @default.
• W2035543265 hasConceptScore W2035543265C185592680 @default.
• W2035543265 hasConceptScore W2035543265C202751555 @default.
• W2035543265 hasConceptScore W2035543265C2777022698 @default.
• W2035543265 hasConceptScore W2035543265C2777411675 @default.
• W2035543265 hasConceptScore W2035543265C29537977 @default.
• W2035543265 hasConceptScore W2035543265C519063684 @default.
• W2035543265 hasConceptScore W2035543265C523546767 @default.
• W2035543265 hasConceptScore W2035543265C54355233 @default.
• W2035543265 hasConceptScore W2035543265C55493867 @default.
• W2035543265 hasConceptScore W2035543265C62112901 @default.
• W2035543265 hasConceptScore W2035543265C73447357 @default.
• W2035543265 hasConceptScore W2035543265C81885089 @default.
• W2035543265 hasConceptScore W2035543265C86803240 @default.
• W2035543265 hasConceptScore W2035543265C95444343 @default.
• W2035543265 hasIssue "2" @default.
• W2035543265 hasLocation W20355432651 @default.
• W2035543265 hasLocation W20355432652 @default.
• W2035543265 hasOpenAccess W2035543265 @default.

• next