Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035549598> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2035549598 abstract "It has previously been shown that in toad epidermis the cell birth rate (Kb) exceeds the rate of cell loss through moulting (Kd) and that the 'surplus' of cells seems to be removed in a controlled manner. Assuming that the epidermis is non-expanding, a Kb/Kd ratio greater than 1 indicates that cell deletion additional to desquamation takes place. In normal toads this ratio is 2-3. Following implantation of hydrocortisone pellets into intact toads (release rate, 18 micrograms/g toad/d), the Kb/Kd ratio, over a period of 14 d of hormone treatment, had increased to about 7, due mainly to an increased Kb and to a lesser extent to a decreased Kd. No change in the epidermal cell pool size had taken place. It was previously shown that, following removal of the pars distalis of the pituitary gland, the Kb/Kd ratio decreased with time, due to a decreasing Kb and an increasing Kd, eventually leading to a decreased epidermal cell pool size. In this paper it is shown that, in pars distalisectomized toads with hydrocortisone pellets implanted, the Kb/Kd ratio is restored to control levels by a restoration of the Kb as well as the Kd. The results differ from those of previous studies in which ACTH or adrenocorticosteroids were administered discontinuously (by injection). Thus, by experimental manipulation, different Kb/Kd ratios can be obtained: low (less than 1, pars distalis ablation), medium (2-3, normal toads) and high (7, hydrocortisone implantation). The potentiality of this unique situation in analysing the important question of how the 'surplus' cells are deleted is discussed." @default.
- W2035549598 created "2016-06-24" @default.
- W2035549598 creator A5062839107 @default.
- W2035549598 date "1988-07-01" @default.
- W2035549598 modified "2023-09-27" @default.
- W2035549598 title "Epidermal Tissue Homeostasis.." @default.
- W2035549598 cites W102100125 @default.
- W2035549598 cites W1970252876 @default.
- W2035549598 cites W1973818792 @default.
- W2035549598 cites W1977140382 @default.
- W2035549598 cites W1977912190 @default.
- W2035549598 cites W1977935956 @default.
- W2035549598 cites W1978800333 @default.
- W2035549598 cites W2003451722 @default.
- W2035549598 cites W2010039538 @default.
- W2035549598 cites W2015467239 @default.
- W2035549598 cites W2025001228 @default.
- W2035549598 cites W2027381404 @default.
- W2035549598 cites W2041822838 @default.
- W2035549598 cites W2053148355 @default.
- W2035549598 cites W2068962888 @default.
- W2035549598 cites W2085183219 @default.
- W2035549598 cites W2086022038 @default.
- W2035549598 cites W2091815501 @default.
- W2035549598 cites W2092995128 @default.
- W2035549598 cites W2129863070 @default.
- W2035549598 cites W2583798591 @default.
- W2035549598 doi "https://doi.org/10.1111/j.1365-2184.1988.tb00785.x" @default.
- W2035549598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3148370" @default.
- W2035549598 hasPublicationYear "1988" @default.
- W2035549598 type Work @default.
- W2035549598 sameAs 2035549598 @default.
- W2035549598 citedByCount "3" @default.
- W2035549598 crossrefType "journal-article" @default.
- W2035549598 hasAuthorship W2035549598A5062839107 @default.
- W2035549598 hasConcept C105702510 @default.
- W2035549598 hasConcept C126322002 @default.
- W2035549598 hasConcept C134018914 @default.
- W2035549598 hasConcept C1491633281 @default.
- W2035549598 hasConcept C173758957 @default.
- W2035549598 hasConcept C2776458125 @default.
- W2035549598 hasConcept C2778166480 @default.
- W2035549598 hasConcept C2778709874 @default.
- W2035549598 hasConcept C41905685 @default.
- W2035549598 hasConcept C55493867 @default.
- W2035549598 hasConcept C59822182 @default.
- W2035549598 hasConcept C71315377 @default.
- W2035549598 hasConcept C71924100 @default.
- W2035549598 hasConcept C86803240 @default.
- W2035549598 hasConceptScore W2035549598C105702510 @default.
- W2035549598 hasConceptScore W2035549598C126322002 @default.
- W2035549598 hasConceptScore W2035549598C134018914 @default.
- W2035549598 hasConceptScore W2035549598C1491633281 @default.
- W2035549598 hasConceptScore W2035549598C173758957 @default.
- W2035549598 hasConceptScore W2035549598C2776458125 @default.
- W2035549598 hasConceptScore W2035549598C2778166480 @default.
- W2035549598 hasConceptScore W2035549598C2778709874 @default.
- W2035549598 hasConceptScore W2035549598C41905685 @default.
- W2035549598 hasConceptScore W2035549598C55493867 @default.
- W2035549598 hasConceptScore W2035549598C59822182 @default.
- W2035549598 hasConceptScore W2035549598C71315377 @default.
- W2035549598 hasConceptScore W2035549598C71924100 @default.
- W2035549598 hasConceptScore W2035549598C86803240 @default.
- W2035549598 hasLocation W20355495981 @default.
- W2035549598 hasLocation W20355495982 @default.
- W2035549598 hasOpenAccess W2035549598 @default.
- W2035549598 hasPrimaryLocation W20355495981 @default.
- W2035549598 hasRelatedWork W1561221726 @default.
- W2035549598 hasRelatedWork W2027210979 @default.
- W2035549598 hasRelatedWork W2048057031 @default.
- W2035549598 hasRelatedWork W2067783814 @default.
- W2035549598 hasRelatedWork W2082671782 @default.
- W2035549598 hasRelatedWork W2114057335 @default.
- W2035549598 hasRelatedWork W2164661085 @default.
- W2035549598 hasRelatedWork W2171315853 @default.
- W2035549598 hasRelatedWork W2171532347 @default.
- W2035549598 hasRelatedWork W2410078069 @default.
- W2035549598 isParatext "false" @default.
- W2035549598 isRetracted "false" @default.
- W2035549598 magId "2035549598" @default.
- W2035549598 workType "article" @default.