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- W2035565538 abstract "Co‐expression of cloned sodium channel β 1 ‐subunit with the rat skeletal muscle‐subunit (α μI ) accelerated the macroscopic current decay, enhanced the current amplitude, shifted the steady state inactivation curve to more negative potentials and decreased the time required for complete recovery from inactivation. Sodium channels expressed from skeletal muscle mRNA showed a similar behaviour to that observed from , indicating that β 1 restores ‘physiological’ behaviour. Northern blot analysis revealed that the Na + channel β 1 ‐subunit is present in high abundance (about 0.1%) in rat heart, brain and skeletal muscle, and the hybridization with untranslated region of the ‘brain’ β 1 cDNA to skeletal muscle and heart mRNA indicated that the diffferent Na + channel α‐subunits in brain, skeletal muscle and heart may share a common β 1 ‐subunit." @default.
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- W2035565538 date "1993-12-28" @default.
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- W2035565538 title "Modulation of the skeletal muscle sodium channel α‐subunit by the β<sub>1</sub> ‐subunit" @default.
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- W2035565538 doi "https://doi.org/10.1016/0014-5793(93)80871-q" @default.
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