FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035569732> ?p ?o ?g. }

• W2035569732 endingPage "727" @default.
• W2035569732 startingPage "717" @default.
• W2035569732 abstract "The activation of the blastocyst, a process by which it gains competency to attach with the receptive uterus, is a prerequisite for successful implantation. However, the molecular basis of blastocyst activation remains largely unexplored. Combining molecular, pharmacological and physiological approaches, we show here that silencing of Wnt-β-catenin signaling in mice does not adversely affect the development of preimplantation embryos to blastocysts and uterine preparation for receptivity, but, remarkably, blocks blastocyst competency to implantation. Using the physiologically relevant delayed implantation model and trophoblast stem cells in culture, we further demonstrate that a coordinated activation of canonical Wnt-β-catenin signaling with attenuation of the non-canonical Wnt-RhoA signaling pathway ensures blastocyst competency to implantation. These findings constitute novel evidence that Wnt signaling is at least one pathway that determines blastocyst competency for implantation." @default.
• W2035569732 created "2016-06-24" @default.
• W2035569732 creator A5044765532 @default.
• W2035569732 creator A5045442544 @default.
• W2035569732 creator A5045593206 @default.
• W2035569732 creator A5049341927 @default.
• W2035569732 creator A5056484501 @default.
• W2035569732 creator A5056685479 @default.
• W2035569732 creator A5063476565 @default.
• W2035569732 creator A5073799238 @default.
• W2035569732 date "2008-02-15" @default.
• W2035569732 modified "2023-10-18" @default.
• W2035569732 title "Inactivation of nuclear Wnt-β-catenin signaling limits blastocyst competency for implantation" @default.
• W2035569732 cites W1513049769 @default.
• W2035569732 cites W1557541313 @default.
• W2035569732 cites W1564357553 @default.
• W2035569732 cites W1589352523 @default.
• W2035569732 cites W1886443720 @default.
• W2035569732 cites W1964841323 @default.
• W2035569732 cites W1975751233 @default.
• W2035569732 cites W1976079453 @default.
• W2035569732 cites W1979201752 @default.
• W2035569732 cites W1982709013 @default.
• W2035569732 cites W1983165815 @default.
• W2035569732 cites W1983712244 @default.
• W2035569732 cites W1990498979 @default.
• W2035569732 cites W1990710362 @default.
• W2035569732 cites W1993677820 @default.
• W2035569732 cites W1994227710 @default.
• W2035569732 cites W1996284495 @default.
• W2035569732 cites W1997085708 @default.
• W2035569732 cites W1998498869 @default.
• W2035569732 cites W1999504956 @default.
• W2035569732 cites W2002404925 @default.
• W2035569732 cites W2015974087 @default.
• W2035569732 cites W2026579311 @default.
• W2035569732 cites W2026787985 @default.
• W2035569732 cites W2029252362 @default.
• W2035569732 cites W2035192365 @default.
• W2035569732 cites W2050223736 @default.
• W2035569732 cites W2051340861 @default.
• W2035569732 cites W2055808176 @default.
• W2035569732 cites W2065342964 @default.
• W2035569732 cites W2068568965 @default.
• W2035569732 cites W2072400772 @default.
• W2035569732 cites W2080397589 @default.
• W2035569732 cites W2082655555 @default.
• W2035569732 cites W2086747507 @default.
• W2035569732 cites W2088971854 @default.
• W2035569732 cites W2092125592 @default.
• W2035569732 cites W2092282322 @default.
• W2035569732 cites W2094484000 @default.
• W2035569732 cites W2117156715 @default.
• W2035569732 cites W2122299286 @default.
• W2035569732 cites W2123829995 @default.
• W2035569732 cites W2126851387 @default.
• W2035569732 cites W2127150853 @default.
• W2035569732 cites W2146788074 @default.
• W2035569732 cites W2149660935 @default.
• W2035569732 cites W2150163104 @default.
• W2035569732 cites W2169019804 @default.
• W2035569732 doi "https://doi.org/10.1242/dev.015339" @default.
• W2035569732 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2829274" @default.
• W2035569732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18199579" @default.
• W2035569732 hasPublicationYear "2008" @default.
• W2035569732 type Work @default.
• W2035569732 sameAs 2035569732 @default.
• W2035569732 citedByCount "160" @default.
• W2035569732 countsByYear W20355697322012 @default.
• W2035569732 countsByYear W20355697322013 @default.
• W2035569732 countsByYear W20355697322014 @default.
• W2035569732 countsByYear W20355697322015 @default.
• W2035569732 countsByYear W20355697322016 @default.
• W2035569732 countsByYear W20355697322017 @default.
• W2035569732 countsByYear W20355697322018 @default.
• W2035569732 countsByYear W20355697322019 @default.
• W2035569732 countsByYear W20355697322020 @default.
• W2035569732 countsByYear W20355697322021 @default.
• W2035569732 countsByYear W20355697322022 @default.
• W2035569732 countsByYear W20355697322023 @default.
• W2035569732 crossrefType "journal-article" @default.
• W2035569732 hasAuthorship W2035569732A5044765532 @default.
• W2035569732 hasAuthorship W2035569732A5045442544 @default.
• W2035569732 hasAuthorship W2035569732A5045593206 @default.
• W2035569732 hasAuthorship W2035569732A5049341927 @default.
• W2035569732 hasAuthorship W2035569732A5056484501 @default.
• W2035569732 hasAuthorship W2035569732A5056685479 @default.
• W2035569732 hasAuthorship W2035569732A5063476565 @default.
• W2035569732 hasAuthorship W2035569732A5073799238 @default.
• W2035569732 hasBestOaLocation W20355697321 @default.
• W2035569732 hasConcept C137620995 @default.
• W2035569732 hasConcept C172680121 @default.
• W2035569732 hasConcept C196843134 @default.
• W2035569732 hasConcept C2776953305 @default.
• W2035569732 hasConcept C2777093181 @default.
• W2035569732 hasConcept C2777495146 @default.
• W2035569732 hasConcept C2778177303 @default.
• W2035569732 hasConcept C2779234561 @default.

• next