FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035588047> ?p ?o ?g. }

• W2035588047 endingPage "371" @default.
• W2035588047 startingPage "333" @default.
• W2035588047 abstract "The last decade has witnessed a renewed interest in the coarse-grained (CG) models for biopolymers, also stimulated by the needs of modern molecular biology, dealing with nano- to micro-sized bio-molecular systems and larger than microsecond timescale. This combination of size and timescale is, in fact, hard to access by atomic-based simulations. Coarse graining the system is a route to be followed to overcome these limits, but the ways of practically implementing it are many and different, making the landscape of CG models very vast and complex. In this paper, the CG models are reviewed and their features, applications and performances compared. This analysis, restricted to proteins, focuses on the minimalist models, namely those reducing at minimum the number of degrees of freedom without losing the possibility of explicitly describing the secondary structures. This class includes models using a single or a few interacting centers (beads) for each amino acid. From this analysis several issues emerge. The difficulty in building these models resides in the need for combining transferability/predictive power with the capability of accurately reproducing the structures. It is shown that these aspects could be optimized by accurately choosing the force field (FF) terms and functional forms, and combining different parameterization procedures. In addition, in spite of the variety of the minimalist models, regularities can be found in the parameters values and in FF terms. These are outlined and schematically presented with the aid of a generic phase diagram of the polypeptide in the parameter space and, hopefully, could serve as guidelines for the development of minimalist models incorporating the maximum possible level of predictive power and structural accuracy." @default.
• W2035588047 created "2016-06-24" @default.
• W2035588047 creator A5025719505 @default.
• W2035588047 date "2010-08-01" @default.
• W2035588047 modified "2023-10-18" @default.
• W2035588047 title "Minimalist models for proteins: a comparative analysis" @default.
• W2035588047 cites W1960408443 @default.
• W2035588047 cites W1965615878 @default.
• W2035588047 cites W1965838279 @default.
• W2035588047 cites W1967450294 @default.
• W2035588047 cites W1972390461 @default.
• W2035588047 cites W1973243106 @default.
• W2035588047 cites W1976214829 @default.
• W2035588047 cites W1986342431 @default.
• W2035588047 cites W1986356457 @default.
• W2035588047 cites W1987153424 @default.
• W2035588047 cites W1988480171 @default.
• W2035588047 cites W1992191950 @default.
• W2035588047 cites W1993321394 @default.
• W2035588047 cites W1996054085 @default.
• W2035588047 cites W1997621425 @default.
• W2035588047 cites W1999138060 @default.
• W2035588047 cites W1999198659 @default.
• W2035588047 cites W2000963503 @default.
• W2035588047 cites W2001449162 @default.
• W2035588047 cites W2003180932 @default.
• W2035588047 cites W2004299515 @default.
• W2035588047 cites W2007961905 @default.
• W2035588047 cites W2009133700 @default.
• W2035588047 cites W2009918603 @default.
• W2035588047 cites W2009997795 @default.
• W2035588047 cites W2014428336 @default.
• W2035588047 cites W2019301610 @default.
• W2035588047 cites W2019729866 @default.
• W2035588047 cites W2024759709 @default.
• W2035588047 cites W2025970642 @default.
• W2035588047 cites W2028267792 @default.
• W2035588047 cites W2028918670 @default.
• W2035588047 cites W2032580068 @default.
• W2035588047 cites W2043697182 @default.
• W2035588047 cites W2047022491 @default.
• W2035588047 cites W2051864856 @default.
• W2035588047 cites W2058101188 @default.
• W2035588047 cites W2058267477 @default.
• W2035588047 cites W2059121391 @default.
• W2035588047 cites W2060036077 @default.
• W2035588047 cites W2065408059 @default.
• W2035588047 cites W2065864578 @default.
• W2035588047 cites W2066005503 @default.
• W2035588047 cites W2069777230 @default.
• W2035588047 cites W2070725100 @default.
• W2035588047 cites W2073911195 @default.
• W2035588047 cites W2076368603 @default.
• W2035588047 cites W2079450846 @default.
• W2035588047 cites W2082028745 @default.
• W2035588047 cites W2082524937 @default.
• W2035588047 cites W2083148298 @default.
• W2035588047 cites W2086975932 @default.
• W2035588047 cites W2087144783 @default.
• W2035588047 cites W2091640762 @default.
• W2035588047 cites W2092640972 @default.
• W2035588047 cites W2095070960 @default.
• W2035588047 cites W2103717543 @default.
• W2035588047 cites W2103723321 @default.
• W2035588047 cites W2103856741 @default.
• W2035588047 cites W2105926633 @default.
• W2035588047 cites W2109610280 @default.
• W2035588047 cites W2113994268 @default.
• W2035588047 cites W2114441129 @default.
• W2035588047 cites W2120451413 @default.
• W2035588047 cites W2121304339 @default.
• W2035588047 cites W2122599408 @default.
• W2035588047 cites W2123035826 @default.
• W2035588047 cites W2125677968 @default.
• W2035588047 cites W2126719129 @default.
• W2035588047 cites W2131578092 @default.
• W2035588047 cites W2138976744 @default.
• W2035588047 cites W2141570358 @default.
• W2035588047 cites W2142694980 @default.
• W2035588047 cites W2142872962 @default.
• W2035588047 cites W2147274570 @default.
• W2035588047 cites W2155988583 @default.
• W2035588047 cites W2156884294 @default.
• W2035588047 cites W2159565091 @default.
• W2035588047 cites W2164248923 @default.
• W2035588047 cites W2168536864 @default.
• W2035588047 cites W2171546617 @default.
• W2035588047 cites W3104005636 @default.
• W2035588047 doi "https://doi.org/10.1017/s0033583510000132" @default.
• W2035588047 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20707940" @default.
• W2035588047 hasPublicationYear "2010" @default.
• W2035588047 type Work @default.
• W2035588047 sameAs 2035588047 @default.
• W2035588047 citedByCount "95" @default.
• W2035588047 countsByYear W20355880472012 @default.
• W2035588047 countsByYear W20355880472013 @default.
• W2035588047 countsByYear W20355880472014 @default.
• W2035588047 countsByYear W20355880472015 @default.

• next