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• W2035596901 abstract "To measure rate constants while performing biomolecular interaction analysis (BIA), scientists often use resonant mirror devices such as the IAsys TM . A full mathematical model of the IAsys TM consists of a convection–diffusion equation in a closed well with a reacting surface at the bottom. The flow in the well is complex, but near the sensor, the qualitative nature of the reaction can be analyzed by reducing to stagnation point flow. The concentration of the reacting species in several cases is analyzed using singular perturbation techniques. Linear and nonlinear integral equations result from the analysis; explicit and series solutions are constructed for physically realizable cases. These solutions, which include the effects of transport on the reaction, provide improved estimates for the rate constants from raw IAsys TM binding data." @default.
• W2035596901 created "2016-06-24" @default.
• W2035596901 creator A5089749626 @default.
• W2035596901 date "2000-07-01" @default.
• W2035596901 modified "2023-10-16" @default.
• W2035596901 title "Surface Reaction Near a Stagnation Point" @default.
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• W2035596901 doi "https://doi.org/10.1111/1467-9590.00139" @default.
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