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- W2035695943 abstract "Abstract Three naturally new C -glycosylated benz[α]anthraquinone derivatives, urdamycinone E ( 1 ), urdamycinone G ( 2 ), dehydroxyaquayamycin ( 3 ) have been isolated from the marine Streptomycetes sp. BCC45596 . Urdamycin E ( 4 ), the possible biosynthetic precursor of 1 – 3 , has also been identified after a re-cultivation of the strain. These compounds ( 1 – 4 ) exhibited potent anti- Plasmodium palcifarum K1 strain with IC 50 values in a range of 0.0534–2.93 μg/mL and anti- Mycobacterium tuberculosis with minimum inhibition concentrations (MICs) in a range of 3.13–12.50 μg/mL. Cytotoxicity against KB, MCF-7, NCI-H187, and Vero cells was also evaluated." @default.
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- W2035695943 date "2012-09-01" @default.
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- W2035695943 title "Antimalarial and antitubercular C-glycosylated benz[α]anthraquinones from the marine-derived Streptomyces sp. BCC45596" @default.
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