Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035720104> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2035720104 endingPage "S95" @default.
- W2035720104 startingPage "S88" @default.
- W2035720104 abstract "Background Mechanical stimuli affected bone adaptation, however, the mechanism on a dose–response relationship between mechanical stimuli and bone response is unclear. Therefore, we established a mechanobiology model to evaluated the adaptive response of bone to strain deformation at high-frequencies (5–15 Hz) of externally applied strain. Methods The ulnae of adult female rats were subjected to dynamic axial loading in vivo using Instron materials-testing machine. The applied loading at frequencies of 5 Hz, 10 Hz, and 15 Hz for 10 min with a haversine, low-magnitude waveform for a 2 weeks period, the peak strains is 2000 με and 3000 με. Strain was recorded using strain gauge conditioner and compared to physiological values obtained after testing. Findings At frequencies of 10 Hz, 15 Hz groups, loading promoted obviously secreted of osteocalcin and collagen; a relative benefit in Bone Mineral Density (BMD) was found compare to the control (P < 0.05) followed the decline of material mechanical properties (modulus of elasticity, ultimate stress) (P < 0.01). Interpretation These data show that a mechanobiology model of the axial ulna loading technique had been established successfully in rat. A short daily period of low-magnitude, high-frequency mechanical stimuli results in an osteogenic response related to peak strain magnitude, which do not result in significant differences in mechanical properties between the groups." @default.
- W2035720104 created "2016-06-24" @default.
- W2035720104 creator A5002874989 @default.
- W2035720104 creator A5008167844 @default.
- W2035720104 creator A5012194230 @default.
- W2035720104 creator A5054512597 @default.
- W2035720104 creator A5056835620 @default.
- W2035720104 creator A5089152634 @default.
- W2035720104 date "2008-01-01" @default.
- W2035720104 modified "2023-10-04" @default.
- W2035720104 title "The establishment of a mechanobiology model of bone and functional adaptation in response to mechanical loading" @default.
- W2035720104 cites W1977106345 @default.
- W2035720104 cites W1980408082 @default.
- W2035720104 cites W1984579670 @default.
- W2035720104 cites W1986746924 @default.
- W2035720104 cites W1996028216 @default.
- W2035720104 cites W1999235348 @default.
- W2035720104 cites W2000036848 @default.
- W2035720104 cites W2012388796 @default.
- W2035720104 cites W2013785685 @default.
- W2035720104 cites W2025199445 @default.
- W2035720104 cites W2027237953 @default.
- W2035720104 cites W2027914516 @default.
- W2035720104 cites W2031543549 @default.
- W2035720104 cites W2043567886 @default.
- W2035720104 cites W2050684881 @default.
- W2035720104 cites W2065915172 @default.
- W2035720104 cites W2081892717 @default.
- W2035720104 cites W2108082833 @default.
- W2035720104 cites W2136537992 @default.
- W2035720104 cites W2146536416 @default.
- W2035720104 cites W2160086148 @default.
- W2035720104 cites W2171705946 @default.
- W2035720104 cites W4248267112 @default.
- W2035720104 doi "https://doi.org/10.1016/j.clinbiomech.2008.01.016" @default.
- W2035720104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18448217" @default.
- W2035720104 hasPublicationYear "2008" @default.
- W2035720104 type Work @default.
- W2035720104 sameAs 2035720104 @default.
- W2035720104 citedByCount "14" @default.
- W2035720104 countsByYear W20357201042012 @default.
- W2035720104 countsByYear W20357201042013 @default.
- W2035720104 countsByYear W20357201042014 @default.
- W2035720104 countsByYear W20357201042015 @default.
- W2035720104 countsByYear W20357201042016 @default.
- W2035720104 countsByYear W20357201042023 @default.
- W2035720104 crossrefType "journal-article" @default.
- W2035720104 hasAuthorship W2035720104A5002874989 @default.
- W2035720104 hasAuthorship W2035720104A5008167844 @default.
- W2035720104 hasAuthorship W2035720104A5012194230 @default.
- W2035720104 hasAuthorship W2035720104A5054512597 @default.
- W2035720104 hasAuthorship W2035720104A5056835620 @default.
- W2035720104 hasAuthorship W2035720104A5089152634 @default.
- W2035720104 hasConcept C105702510 @default.
- W2035720104 hasConcept C121854251 @default.
- W2035720104 hasConcept C136229726 @default.
- W2035720104 hasConcept C159985019 @default.
- W2035720104 hasConcept C170700871 @default.
- W2035720104 hasConcept C192562407 @default.
- W2035720104 hasConcept C2777695862 @default.
- W2035720104 hasConcept C2778022156 @default.
- W2035720104 hasConcept C2780171871 @default.
- W2035720104 hasConcept C60584519 @default.
- W2035720104 hasConcept C71924100 @default.
- W2035720104 hasConceptScore W2035720104C105702510 @default.
- W2035720104 hasConceptScore W2035720104C121854251 @default.
- W2035720104 hasConceptScore W2035720104C136229726 @default.
- W2035720104 hasConceptScore W2035720104C159985019 @default.
- W2035720104 hasConceptScore W2035720104C170700871 @default.
- W2035720104 hasConceptScore W2035720104C192562407 @default.
- W2035720104 hasConceptScore W2035720104C2777695862 @default.
- W2035720104 hasConceptScore W2035720104C2778022156 @default.
- W2035720104 hasConceptScore W2035720104C2780171871 @default.
- W2035720104 hasConceptScore W2035720104C60584519 @default.
- W2035720104 hasConceptScore W2035720104C71924100 @default.
- W2035720104 hasLocation W20357201041 @default.
- W2035720104 hasLocation W20357201042 @default.
- W2035720104 hasOpenAccess W2035720104 @default.
- W2035720104 hasPrimaryLocation W20357201041 @default.
- W2035720104 hasRelatedWork W1958946079 @default.
- W2035720104 hasRelatedWork W2043701551 @default.
- W2035720104 hasRelatedWork W2128382865 @default.
- W2035720104 hasRelatedWork W2137307547 @default.
- W2035720104 hasRelatedWork W2333304939 @default.
- W2035720104 hasRelatedWork W2380293314 @default.
- W2035720104 hasRelatedWork W2943188944 @default.
- W2035720104 hasRelatedWork W3082440218 @default.
- W2035720104 hasRelatedWork W3115047389 @default.
- W2035720104 hasRelatedWork W4214556957 @default.
- W2035720104 hasVolume "23" @default.
- W2035720104 isParatext "false" @default.
- W2035720104 isRetracted "false" @default.
- W2035720104 magId "2035720104" @default.
- W2035720104 workType "article" @default.