FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035741511> ?p ?o ?g. }

• W2035741511 endingPage "2538" @default.
• W2035741511 startingPage "2519" @default.
• W2035741511 abstract "The replacement of petrochemicals with biobased chemicals requires efficient bioprocesses, biocatalysis, and product recovery. Biocatalysis (e.g., enzyme conversion and fermentation) offers an attractive alternative to chemical processing because biocatalysis utilize renewable feedstocks under benign reaction conditions. One class of chemical products that could be produced in large volumes by biocatalysis is organic acids. However, biocatalytic reactions to produce organic acids typically result in only dilute concentrations of the product because of product inhibition and acidification that drives the reaction pH outside of the optimal range for the biocatalyst. Buffering or neutralization results in formation of the acid salt rather than the acid, which requires further processing to recover the free acid product. To address these barriers to biocatalytic organic acid production, we developed the separative bioreactor based on resin wafer electrodeionization, which is an electro-deionization platform that uses resin wafers fabricated from ion exchange resins. The separative bioreactor simultaneously separates the organic acid from the biocatalyst as it is produced, thus it avoids product inhibition enhancing reaction rates. In addition, the separative bioreactor recovers the product in its acid form to avoid neutralization. The instantaneous separation of acid upon formation in the separative bioreactor is one of the first truly one-step systems for producing organic acids. The separative bioreactor was demonstrated with two systems. In the first demonstration, the enzyme glucose fructose oxidoreductase (GFOR) was immobilized in the reactor and later regenerated in situ. GFOR produced gluconic acid (in its acid form) continuously for 7 days with production rates up to 1000 mg/L/hr at >99% product recovery and GFOR reactivity >30mg gluconic acid/mg GFOR/hour. In the second demonstration, the E. coli strain CSM1 produced lactic acid for up to 24 hours with a productivity of >200 mg/L/hr and almost 100% product recovery." @default.
• W2035741511 created "2016-06-24" @default.
• W2035741511 creator A5011433394 @default.
• W2035741511 creator A5030971942 @default.
• W2035741511 creator A5036688529 @default.
• W2035741511 creator A5036824493 @default.
• W2035741511 creator A5055391346 @default.
• W2035741511 creator A5059614935 @default.
• W2035741511 creator A5071156198 @default.
• W2035741511 date "2007-07-01" @default.
• W2035741511 modified "2023-10-14" @default.
• W2035741511 title "The Separative Bioreactor: A Continuous Separation Process for the Simultaneous Production and Direct Capture of Organic Acids" @default.
• W2035741511 cites W1652052270 @default.
• W2035741511 cites W1882966757 @default.
• W2035741511 cites W1973319968 @default.
• W2035741511 cites W1977259414 @default.
• W2035741511 cites W1981794595 @default.
• W2035741511 cites W1996238052 @default.
• W2035741511 cites W1998801264 @default.
• W2035741511 cites W2001308451 @default.
• W2035741511 cites W2005075723 @default.
• W2035741511 cites W2008370751 @default.
• W2035741511 cites W2022165616 @default.
• W2035741511 cites W2022558703 @default.
• W2035741511 cites W2025812842 @default.
• W2035741511 cites W2070855513 @default.
• W2035741511 cites W2071965332 @default.
• W2035741511 cites W2085112019 @default.
• W2035741511 cites W2086876467 @default.
• W2035741511 cites W2089128540 @default.
• W2035741511 cites W2089488025 @default.
• W2035741511 cites W2090360695 @default.
• W2035741511 cites W2092348178 @default.
• W2035741511 cites W2093010585 @default.
• W2035741511 cites W2097100200 @default.
• W2035741511 cites W2100227304 @default.
• W2035741511 cites W2119053455 @default.
• W2035741511 cites W2141741411 @default.
• W2035741511 cites W2168026634 @default.
• W2035741511 cites W264071584 @default.
• W2035741511 cites W2907158604 @default.
• W2035741511 cites W332633978 @default.
• W2035741511 doi "https://doi.org/10.1080/01496390701477238" @default.
• W2035741511 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3662075" @default.
• W2035741511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23723533" @default.
• W2035741511 hasPublicationYear "2007" @default.
• W2035741511 type Work @default.
• W2035741511 sameAs 2035741511 @default.
• W2035741511 citedByCount "43" @default.
• W2035741511 countsByYear W20357415112012 @default.
• W2035741511 countsByYear W20357415112013 @default.
• W2035741511 countsByYear W20357415112014 @default.
• W2035741511 countsByYear W20357415112015 @default.
• W2035741511 countsByYear W20357415112016 @default.
• W2035741511 countsByYear W20357415112017 @default.
• W2035741511 countsByYear W20357415112018 @default.
• W2035741511 countsByYear W20357415112019 @default.
• W2035741511 countsByYear W20357415112020 @default.
• W2035741511 countsByYear W20357415112021 @default.
• W2035741511 countsByYear W20357415112022 @default.
• W2035741511 countsByYear W20357415112023 @default.
• W2035741511 crossrefType "journal-article" @default.
• W2035741511 hasAuthorship W2035741511A5011433394 @default.
• W2035741511 hasAuthorship W2035741511A5030971942 @default.
• W2035741511 hasAuthorship W2035741511A5036688529 @default.
• W2035741511 hasAuthorship W2035741511A5036824493 @default.
• W2035741511 hasAuthorship W2035741511A5055391346 @default.
• W2035741511 hasAuthorship W2035741511A5059614935 @default.
• W2035741511 hasAuthorship W2035741511A5071156198 @default.
• W2035741511 hasBestOaLocation W20357415111 @default.
• W2035741511 hasConcept C150757390 @default.
• W2035741511 hasConcept C154881586 @default.
• W2035741511 hasConcept C161790260 @default.
• W2035741511 hasConcept C168170006 @default.
• W2035741511 hasConcept C178790620 @default.
• W2035741511 hasConcept C181199279 @default.
• W2035741511 hasConcept C185592680 @default.
• W2035741511 hasConcept C191503008 @default.
• W2035741511 hasConcept C2780388412 @default.
• W2035741511 hasConcept C2780434155 @default.
• W2035741511 hasConcept C43617362 @default.
• W2035741511 hasConceptScore W2035741511C150757390 @default.
• W2035741511 hasConceptScore W2035741511C154881586 @default.
• W2035741511 hasConceptScore W2035741511C161790260 @default.
• W2035741511 hasConceptScore W2035741511C168170006 @default.
• W2035741511 hasConceptScore W2035741511C178790620 @default.
• W2035741511 hasConceptScore W2035741511C181199279 @default.
• W2035741511 hasConceptScore W2035741511C185592680 @default.
• W2035741511 hasConceptScore W2035741511C191503008 @default.
• W2035741511 hasConceptScore W2035741511C2780388412 @default.
• W2035741511 hasConceptScore W2035741511C2780434155 @default.
• W2035741511 hasConceptScore W2035741511C43617362 @default.
• W2035741511 hasIssue "11" @default.
• W2035741511 hasLocation W20357415111 @default.
• W2035741511 hasLocation W20357415112 @default.
• W2035741511 hasLocation W20357415113 @default.
• W2035741511 hasLocation W20357415114 @default.
• W2035741511 hasOpenAccess W2035741511 @default.

• next