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- W2035760367 abstract "The title alkaloid was synthesized in racemic form from 3,7-diallyl-2,4,6,8-tetraoxo-3,7-diazabicyclo[3.3.1]nonane (7) by a regioselective diallylation reaction followed by double ring-closing olefin metathesis and exhaustive reduction. Tetraoxobispidine 7 was itself prepared in three simple operations from dimethyl malonate. The entire sequence to α-isosparteine was conducted on a multigram scale and proceeded without recourse to chromatography." @default.
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- W2035760367 date "2005-09-13" @default.
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- W2035760367 title "A Practical Synthesis of (±)-α-Isosparteine from a Tetraoxobispidine Core" @default.
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- W2035760367 doi "https://doi.org/10.1021/ol0519184" @default.
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