Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035761443> ?p ?o ?g. }
- W2035761443 endingPage "365" @default.
- W2035761443 startingPage "353" @default.
- W2035761443 abstract "The environmental enrichment (EE) paradigm is widely used to study experience-dependent brain plasticity. Several studies have investigated functional and anatomical EE effects. However, as EE effects are different according to cerebral region, cortical layer, dendritic field and morphological index considered, a univocal characterization of neuronal morphological changes following rearing in enriched environments is lacking. Aim of the present study was to characterize in the rat the effects of EE on the neuronal morphology of frontal and parietal cortical regions, the main target areas of the stimulation provided by the paradigm. Male Wistar rats were housed in an enriched environment for 3.5 months from the 21st postnatal day. For the morphological analysis, biotinylated dextran amine (BDA)-labeled pyramidal neurons were selected from frontal (M1–M2) and parietal (S1–S2) cortical layers III and V. Apical and basal dendritic branching and spines were analyzed using the Sholl method. Results showed that EE increased branching and spines in both layers of frontal cortex, but had a greater effect on apical arborization. In parietal cortex, EE significantly affected branching and spines in layer III but not layer V neurons, in which only a tendency to be influenced by the rearing conditions was observed in basal arborization. It is hypothesized that these multifaceted morphological EE effects are connected to the heavy involvement of a sensory-motor circuit engaged in the guidance of voluntary action and in motor learning activated by EE stimulation." @default.
- W2035761443 created "2016-06-24" @default.
- W2035761443 creator A5002973726 @default.
- W2035761443 creator A5019819070 @default.
- W2035761443 creator A5024301232 @default.
- W2035761443 creator A5059388096 @default.
- W2035761443 creator A5074533920 @default.
- W2035761443 date "2009-05-01" @default.
- W2035761443 modified "2023-10-13" @default.
- W2035761443 title "Layer and regional effects of environmental enrichment on the pyramidal neuron morphology of the rat" @default.
- W2035761443 cites W1481984979 @default.
- W2035761443 cites W1969077909 @default.
- W2035761443 cites W1971366695 @default.
- W2035761443 cites W1974544889 @default.
- W2035761443 cites W1974759530 @default.
- W2035761443 cites W1986924194 @default.
- W2035761443 cites W1990909279 @default.
- W2035761443 cites W1990996190 @default.
- W2035761443 cites W1994059402 @default.
- W2035761443 cites W1995918704 @default.
- W2035761443 cites W1996026657 @default.
- W2035761443 cites W1996606735 @default.
- W2035761443 cites W1997568039 @default.
- W2035761443 cites W2006129024 @default.
- W2035761443 cites W2009833394 @default.
- W2035761443 cites W2010055561 @default.
- W2035761443 cites W2017782835 @default.
- W2035761443 cites W2017865145 @default.
- W2035761443 cites W2018800927 @default.
- W2035761443 cites W2020996956 @default.
- W2035761443 cites W2025828736 @default.
- W2035761443 cites W2027365841 @default.
- W2035761443 cites W2032324712 @default.
- W2035761443 cites W2032630122 @default.
- W2035761443 cites W2033344673 @default.
- W2035761443 cites W2034120829 @default.
- W2035761443 cites W2035275790 @default.
- W2035761443 cites W2038112334 @default.
- W2035761443 cites W2040399589 @default.
- W2035761443 cites W2041320147 @default.
- W2035761443 cites W2043450839 @default.
- W2035761443 cites W2044715983 @default.
- W2035761443 cites W2045926717 @default.
- W2035761443 cites W2046963262 @default.
- W2035761443 cites W2048525192 @default.
- W2035761443 cites W2052300068 @default.
- W2035761443 cites W2052617402 @default.
- W2035761443 cites W2054246163 @default.
- W2035761443 cites W2054282296 @default.
- W2035761443 cites W2054944161 @default.
- W2035761443 cites W2057361706 @default.
- W2035761443 cites W2058873342 @default.
- W2035761443 cites W2060977221 @default.
- W2035761443 cites W2063890106 @default.
- W2035761443 cites W2067576490 @default.
- W2035761443 cites W2072672328 @default.
- W2035761443 cites W2074764259 @default.
- W2035761443 cites W2078075878 @default.
- W2035761443 cites W2078490096 @default.
- W2035761443 cites W2078529082 @default.
- W2035761443 cites W2081896689 @default.
- W2035761443 cites W2083137364 @default.
- W2035761443 cites W2083168908 @default.
- W2035761443 cites W2083194463 @default.
- W2035761443 cites W2087438990 @default.
- W2035761443 cites W2088523542 @default.
- W2035761443 cites W2090490936 @default.
- W2035761443 cites W2096192426 @default.
- W2035761443 cites W2106159603 @default.
- W2035761443 cites W2113783170 @default.
- W2035761443 cites W2122462571 @default.
- W2035761443 cites W2126125886 @default.
- W2035761443 cites W2133406691 @default.
- W2035761443 cites W2137979527 @default.
- W2035761443 cites W2141711957 @default.
- W2035761443 cites W2143072133 @default.
- W2035761443 cites W2146437238 @default.
- W2035761443 cites W2154908600 @default.
- W2035761443 cites W2156621206 @default.
- W2035761443 cites W2743059607 @default.
- W2035761443 cites W4251861184 @default.
- W2035761443 doi "https://doi.org/10.1016/j.nlm.2009.01.010" @default.
- W2035761443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19340947" @default.
- W2035761443 hasPublicationYear "2009" @default.
- W2035761443 type Work @default.
- W2035761443 sameAs 2035761443 @default.
- W2035761443 citedByCount "78" @default.
- W2035761443 countsByYear W20357614432012 @default.
- W2035761443 countsByYear W20357614432013 @default.
- W2035761443 countsByYear W20357614432014 @default.
- W2035761443 countsByYear W20357614432015 @default.
- W2035761443 countsByYear W20357614432016 @default.
- W2035761443 countsByYear W20357614432017 @default.
- W2035761443 countsByYear W20357614432018 @default.
- W2035761443 countsByYear W20357614432019 @default.
- W2035761443 countsByYear W20357614432020 @default.
- W2035761443 countsByYear W20357614432021 @default.
- W2035761443 countsByYear W20357614432022 @default.