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• W2035787645 endingPage "298" @default.
• W2035787645 startingPage "287" @default.
• W2035787645 abstract "The effects of intravenous administration of the anticholinesterase agent soman (pinacolyl methylphosphonofluoridate, 3–15 μg/kg) on the visual evoked potential (VEP) were examined in cats using phase-reversed sine wave grating stimuli of different spatial frequencies and contrasts. Doses of 5–7 μg/kg caused a depression of the VEP across all spatial frequencies in an abrupt, non-graded fashion. Studies in which contrast was varied showed that VEP depression resulted primarily from a decrease in the system gain rather than a change in the contrast sensitivity, and that response depression increased with increasing contrast. The dominant changes in gain revealed by these studies are consistent with a modulation of potassium conductance in the cell membrane which previous studies have shown to be dependent on a cholinergic mechanism." @default.
• W2035787645 created "2016-06-24" @default.
• W2035787645 creator A5008063927 @default.
• W2035787645 creator A5015898875 @default.
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• W2035787645 date "1954-01-01" @default.
• W2035787645 modified "2023-09-23" @default.
• W2035787645 title "Augmentation of evoked cortical potentials by topical application of prostigmine and acetylcholine after atropinization of cortex" @default.
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• W2035787645 doi "https://doi.org/10.1016/0013-4694(54)90030-9" @default.
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• W2035787645 hasPublicationYear "1954" @default.
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