FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035942802> ?p ?o ?g. }

• W2035942802 endingPage "187" @default.
• W2035942802 startingPage "179" @default.
• W2035942802 abstract "Drugs with anticonvulsive properties and different mechanisms of action were compared for their influence on long-term potentiation and pentylenetetrazol kindling in freely moving animals. Rats were chronically implanted with a stimulation electrode in the angular bundle and a recording electrode in the dentate gyrus. Field potentials in the dentate gyrus were elicited and long-term potentiation was induced by stimulation of the perforant pathway. The clinically used drugs or the potentially anticonvulsive drugs, diphenylhydantoin (50 mg/kg), diazepam (0.5 mg/kg), pentobarbital (10 mg/kg), dizocilpine (MK 801, 0.2 mg/kg) and CGP 43487 (2-amino-4-methyl-5-phosphono-3-pentenoic acid-carboxyethylester, 10 mg/kg), were injected before tetanization. In behavioural experiments pentylenetetrazol kindling was performed with pretreatment with the substances in dosages indicated above (except MK 801, 0.3 mg/kg). Field potentials recorded in the interval between drug administration and tetanization were influenced only by diphenylhydantoin which enhanced the population spike amplitude to 128% of control values. However, the substances showed different effects on long-term potentiation. MK 801, CGP 43487 and pentobarbital depressed potentiation; diazepam was without effect. Diphenylhydantoin had a minor influence on induction but significantly impaired maintenance of long-term potentiation. Furthermore, MK 801, CGP 43487, diazepam and pentobarbital differentially depressed kindling whereas phenytoin only slightly influenced it. The consequences as to hypothetical common cellular mechanisms for kindling development and long-term potentiation are discussed." @default.
• W2035942802 created "2016-06-24" @default.
• W2035942802 creator A5006053528 @default.
• W2035942802 creator A5036562682 @default.
• W2035942802 creator A5045490528 @default.
• W2035942802 creator A5073351502 @default.
• W2035942802 creator A5078722723 @default.
• W2035942802 creator A5080331698 @default.
• W2035942802 date "1998-09-01" @default.
• W2035942802 modified "2023-10-04" @default.
• W2035942802 title "Effects of anticonvulsive drugs on pentylenetetrazol kindling and long-term potentiation in freely moving rats" @default.
• W2035942802 cites W1531783246 @default.
• W2035942802 cites W1965721266 @default.
• W2035942802 cites W1966224996 @default.
• W2035942802 cites W1969650371 @default.
• W2035942802 cites W1974728729 @default.
• W2035942802 cites W1975911537 @default.
• W2035942802 cites W1978074981 @default.
• W2035942802 cites W1980133293 @default.
• W2035942802 cites W1980798138 @default.
• W2035942802 cites W1982705853 @default.
• W2035942802 cites W1984375763 @default.
• W2035942802 cites W1984376917 @default.
• W2035942802 cites W1984783225 @default.
• W2035942802 cites W1988596834 @default.
• W2035942802 cites W1992317046 @default.
• W2035942802 cites W1994855739 @default.
• W2035942802 cites W1994869219 @default.
• W2035942802 cites W2010451913 @default.
• W2035942802 cites W2011169245 @default.
• W2035942802 cites W2013013267 @default.
• W2035942802 cites W2013381736 @default.
• W2035942802 cites W2014649977 @default.
• W2035942802 cites W2019849882 @default.
• W2035942802 cites W2025801062 @default.
• W2035942802 cites W2026501837 @default.
• W2035942802 cites W2044611676 @default.
• W2035942802 cites W2046941363 @default.
• W2035942802 cites W2047499532 @default.
• W2035942802 cites W2049511526 @default.
• W2035942802 cites W2049594669 @default.
• W2035942802 cites W2049735948 @default.
• W2035942802 cites W2054788474 @default.
• W2035942802 cites W2056060189 @default.
• W2035942802 cites W2061722255 @default.
• W2035942802 cites W2078222731 @default.
• W2035942802 cites W2084182228 @default.
• W2035942802 cites W2085490867 @default.
• W2035942802 cites W2090852940 @default.
• W2035942802 cites W2092902105 @default.
• W2035942802 cites W2093003597 @default.
• W2035942802 cites W2147180615 @default.
• W2035942802 cites W2155844685 @default.
• W2035942802 cites W2175272720 @default.
• W2035942802 cites W2084697525 @default.
• W2035942802 doi "https://doi.org/10.1016/s0014-2999(98)00544-5" @default.
• W2035942802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9774247" @default.
• W2035942802 hasPublicationYear "1998" @default.
• W2035942802 type Work @default.
• W2035942802 sameAs 2035942802 @default.
• W2035942802 citedByCount "18" @default.
• W2035942802 countsByYear W20359428022012 @default.
• W2035942802 countsByYear W20359428022015 @default.
• W2035942802 countsByYear W20359428022022 @default.
• W2035942802 crossrefType "journal-article" @default.
• W2035942802 hasAuthorship W2035942802A5006053528 @default.
• W2035942802 hasAuthorship W2035942802A5036562682 @default.
• W2035942802 hasAuthorship W2035942802A5045490528 @default.
• W2035942802 hasAuthorship W2035942802A5073351502 @default.
• W2035942802 hasAuthorship W2035942802A5078722723 @default.
• W2035942802 hasAuthorship W2035942802A5080331698 @default.
• W2035942802 hasConcept C100691959 @default.
• W2035942802 hasConcept C15744967 @default.
• W2035942802 hasConcept C169760540 @default.
• W2035942802 hasConcept C170493617 @default.
• W2035942802 hasConcept C185592680 @default.
• W2035942802 hasConcept C24998067 @default.
• W2035942802 hasConcept C25274449 @default.
• W2035942802 hasConcept C2775858608 @default.
• W2035942802 hasConcept C2776175493 @default.
• W2035942802 hasConcept C2776464000 @default.
• W2035942802 hasConcept C2776755955 @default.
• W2035942802 hasConcept C2776819090 @default.
• W2035942802 hasConcept C2778186239 @default.
• W2035942802 hasConcept C2779277159 @default.
• W2035942802 hasConcept C2781161787 @default.
• W2035942802 hasConcept C55493867 @default.
• W2035942802 hasConcept C71924100 @default.
• W2035942802 hasConcept C98274493 @default.
• W2035942802 hasConceptScore W2035942802C100691959 @default.
• W2035942802 hasConceptScore W2035942802C15744967 @default.
• W2035942802 hasConceptScore W2035942802C169760540 @default.
• W2035942802 hasConceptScore W2035942802C170493617 @default.
• W2035942802 hasConceptScore W2035942802C185592680 @default.
• W2035942802 hasConceptScore W2035942802C24998067 @default.
• W2035942802 hasConceptScore W2035942802C25274449 @default.
• W2035942802 hasConceptScore W2035942802C2775858608 @default.
• W2035942802 hasConceptScore W2035942802C2776175493 @default.

• next