Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035992790> ?p ?o ?g. }
- W2035992790 endingPage "669" @default.
- W2035992790 startingPage "661" @default.
- W2035992790 abstract "The human placental syncytiotrophoblast is the main site of exchange of nutrients and minerals between the mother and her fetus. In order to characterize the placental transport of some fatty acids, we studied the incorporation of arachidonic acid, a fetal primordial fatty acid, in purified bipolar syncytiotrophoblast brush border (BBM) and basal plasma membranes (BPM) from human placenta. The basal arachidonic acid incorporation in BBM and BPM was time dependent and reached maximal values of 0.75+/-0.10 and 0.48+/-0.18 pmol/mg protein, respectively, after 2.5 min. The presence of adenosine triphosphate (ATP) (3 m m) increases significantly the maximal incorporation of arachidonic acid by sixfold (4.75+/-0.35 pmol/mg) and ninefold (4.40+/-0.84 pmol/mg) in BBM and BPM, respectively. Moreover, an increase in the arachidonic acid incorporation was also obtained in the presence of sodium where the values achieved 7.68+/-0.98 (10x) and 6.53 pmol/mg (13.6x) for BBM and BPM, respectively. We also showed that the combination of both Na(+)and ATP increases significantly the maximal incorporation of arachidonic acid in BPM to 7.89+/-0.15 pmol/mg protein, while in BBM it did not modify its incorporation (8.18+/-0.25 pmol/mg protein), as compared to the presence of sodium alone. Our results demonstrate that arachidonic acid is incorporated by both placental syncytiotrophoblast membranes, and is ATP and sodium-linked. However, different mechanisms seem to be involved in this fatty acid incorporation through BBM and BPM, since the presence of Na(+)or ATP increased it, while the association of these two elements increased it only in BPM. We also demonstrated by osmolarity experiments that both membranes bind arachidonic acid, potentially involving one or more fatty acids binding proteins." @default.
- W2035992790 created "2016-06-24" @default.
- W2035992790 creator A5029240510 @default.
- W2035992790 creator A5030530754 @default.
- W2035992790 creator A5031255435 @default.
- W2035992790 creator A5032893439 @default.
- W2035992790 creator A5045783932 @default.
- W2035992790 creator A5047616149 @default.
- W2035992790 creator A5047984123 @default.
- W2035992790 creator A5070122542 @default.
- W2035992790 date "2000-09-01" @default.
- W2035992790 modified "2023-10-17" @default.
- W2035992790 title "Implication of ATP and Sodium in Arachidonic Acid Incorporation by Placental Syncytiotrophoblast Brush Border and Basal Plasma Membranes in the Human" @default.
- W2035992790 cites W1042903243 @default.
- W2035992790 cites W1512516272 @default.
- W2035992790 cites W1529891037 @default.
- W2035992790 cites W1537865659 @default.
- W2035992790 cites W1562680772 @default.
- W2035992790 cites W1571945051 @default.
- W2035992790 cites W1599020591 @default.
- W2035992790 cites W1966722575 @default.
- W2035992790 cites W1967602315 @default.
- W2035992790 cites W1973266617 @default.
- W2035992790 cites W1973510821 @default.
- W2035992790 cites W1980511202 @default.
- W2035992790 cites W1985340320 @default.
- W2035992790 cites W1985698954 @default.
- W2035992790 cites W1991522933 @default.
- W2035992790 cites W1992530034 @default.
- W2035992790 cites W1995277155 @default.
- W2035992790 cites W1997783186 @default.
- W2035992790 cites W1998462200 @default.
- W2035992790 cites W1999601012 @default.
- W2035992790 cites W1999610370 @default.
- W2035992790 cites W2007633562 @default.
- W2035992790 cites W2008999317 @default.
- W2035992790 cites W2009972546 @default.
- W2035992790 cites W2028046796 @default.
- W2035992790 cites W2039561810 @default.
- W2035992790 cites W2046157200 @default.
- W2035992790 cites W2050229245 @default.
- W2035992790 cites W2052528465 @default.
- W2035992790 cites W2053687970 @default.
- W2035992790 cites W2054728595 @default.
- W2035992790 cites W2056898007 @default.
- W2035992790 cites W2059129100 @default.
- W2035992790 cites W2059656737 @default.
- W2035992790 cites W2062293834 @default.
- W2035992790 cites W2068981361 @default.
- W2035992790 cites W2079937117 @default.
- W2035992790 cites W2080897141 @default.
- W2035992790 cites W2089058231 @default.
- W2035992790 cites W2092450752 @default.
- W2035992790 cites W2102690567 @default.
- W2035992790 cites W2119432184 @default.
- W2035992790 cites W2147363557 @default.
- W2035992790 cites W2412210005 @default.
- W2035992790 cites W4293247451 @default.
- W2035992790 doi "https://doi.org/10.1053/plac.2000.0561" @default.
- W2035992790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10985969" @default.
- W2035992790 hasPublicationYear "2000" @default.
- W2035992790 type Work @default.
- W2035992790 sameAs 2035992790 @default.
- W2035992790 citedByCount "24" @default.
- W2035992790 countsByYear W20359927902015 @default.
- W2035992790 countsByYear W20359927902016 @default.
- W2035992790 countsByYear W20359927902017 @default.
- W2035992790 countsByYear W20359927902018 @default.
- W2035992790 countsByYear W20359927902022 @default.
- W2035992790 crossrefType "journal-article" @default.
- W2035992790 hasAuthorship W2035992790A5029240510 @default.
- W2035992790 hasAuthorship W2035992790A5030530754 @default.
- W2035992790 hasAuthorship W2035992790A5031255435 @default.
- W2035992790 hasAuthorship W2035992790A5032893439 @default.
- W2035992790 hasAuthorship W2035992790A5045783932 @default.
- W2035992790 hasAuthorship W2035992790A5047616149 @default.
- W2035992790 hasAuthorship W2035992790A5047984123 @default.
- W2035992790 hasAuthorship W2035992790A5070122542 @default.
- W2035992790 hasConcept C126322002 @default.
- W2035992790 hasConcept C130316041 @default.
- W2035992790 hasConcept C134018914 @default.
- W2035992790 hasConcept C172680121 @default.
- W2035992790 hasConcept C178790620 @default.
- W2035992790 hasConcept C181199279 @default.
- W2035992790 hasConcept C185592680 @default.
- W2035992790 hasConcept C2776953305 @default.
- W2035992790 hasConcept C2778078955 @default.
- W2035992790 hasConcept C2779234561 @default.
- W2035992790 hasConcept C2779315647 @default.
- W2035992790 hasConcept C41625074 @default.
- W2035992790 hasConcept C537181965 @default.
- W2035992790 hasConcept C5426402 @default.
- W2035992790 hasConcept C543025807 @default.
- W2035992790 hasConcept C54355233 @default.
- W2035992790 hasConcept C55493867 @default.
- W2035992790 hasConcept C71924100 @default.
- W2035992790 hasConcept C86803240 @default.
- W2035992790 hasConceptScore W2035992790C126322002 @default.