Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035999724> ?p ?o ?g. }
- W2035999724 endingPage "490" @default.
- W2035999724 startingPage "480" @default.
- W2035999724 abstract "A simple and very efficient protein design strategy is proposed by developing some recently introduced theoretical tools which have been successfully applied to exactly solvable protein models. The design approach is implemented by using three amino acid classes and it is based on the minimization of an appropriate energy function. For a given native state the results of the design procedure are compared, through a statistical analysis, with the properties of an ensemble of sequences folding in the same conformation. If the success rate is computed on those sites designed with high confidence, it can be as high as 80%. The method is also able to identify key sites for the folding process: results for 2ci2 and barnase are in very good agreement with experimental results." @default.
- W2035999724 created "2016-06-24" @default.
- W2035999724 creator A5049612522 @default.
- W2035999724 creator A5076985100 @default.
- W2035999724 creator A5083284785 @default.
- W2035999724 creator A5091030212 @default.
- W2035999724 date "2001-01-01" @default.
- W2035999724 modified "2023-09-30" @default.
- W2035999724 title "A Self-Consistent Knowledge-Based Approach to Protein Design" @default.
- W2035999724 cites W1504780538 @default.
- W2035999724 cites W1508885706 @default.
- W2035999724 cites W1551993407 @default.
- W2035999724 cites W1605399271 @default.
- W2035999724 cites W1973272335 @default.
- W2035999724 cites W1984148408 @default.
- W2035999724 cites W1984313562 @default.
- W2035999724 cites W1984527736 @default.
- W2035999724 cites W1989300794 @default.
- W2035999724 cites W1995487418 @default.
- W2035999724 cites W1996576490 @default.
- W2035999724 cites W2002698756 @default.
- W2035999724 cites W2007851849 @default.
- W2035999724 cites W2008097610 @default.
- W2035999724 cites W2008799568 @default.
- W2035999724 cites W2009186593 @default.
- W2035999724 cites W2011357411 @default.
- W2035999724 cites W2014059004 @default.
- W2035999724 cites W2016704620 @default.
- W2035999724 cites W2023235722 @default.
- W2035999724 cites W2040823078 @default.
- W2035999724 cites W2042380360 @default.
- W2035999724 cites W2045091067 @default.
- W2035999724 cites W2045777307 @default.
- W2035999724 cites W2054882585 @default.
- W2035999724 cites W2059681116 @default.
- W2035999724 cites W2060100112 @default.
- W2035999724 cites W2060778016 @default.
- W2035999724 cites W2063937171 @default.
- W2035999724 cites W2064418420 @default.
- W2035999724 cites W2071256770 @default.
- W2035999724 cites W2071436951 @default.
- W2035999724 cites W2077676511 @default.
- W2035999724 cites W2085497102 @default.
- W2035999724 cites W2090304431 @default.
- W2035999724 cites W2092637963 @default.
- W2035999724 cites W2099254366 @default.
- W2035999724 cites W2102310440 @default.
- W2035999724 cites W2114899912 @default.
- W2035999724 cites W2121061814 @default.
- W2035999724 cites W2146606022 @default.
- W2035999724 cites W2162435335 @default.
- W2035999724 doi "https://doi.org/10.1016/s0006-3495(01)76030-4" @default.
- W2035999724 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1301249" @default.
- W2035999724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11159418" @default.
- W2035999724 hasPublicationYear "2001" @default.
- W2035999724 type Work @default.
- W2035999724 sameAs 2035999724 @default.
- W2035999724 citedByCount "20" @default.
- W2035999724 countsByYear W20359997242016 @default.
- W2035999724 countsByYear W20359997242017 @default.
- W2035999724 countsByYear W20359997242021 @default.
- W2035999724 countsByYear W20359997242022 @default.
- W2035999724 crossrefType "journal-article" @default.
- W2035999724 hasAuthorship W2035999724A5049612522 @default.
- W2035999724 hasAuthorship W2035999724A5076985100 @default.
- W2035999724 hasAuthorship W2035999724A5083284785 @default.
- W2035999724 hasAuthorship W2035999724A5091030212 @default.
- W2035999724 hasBestOaLocation W20359997241 @default.
- W2035999724 hasConcept C104317684 @default.
- W2035999724 hasConcept C111472728 @default.
- W2035999724 hasConcept C111919701 @default.
- W2035999724 hasConcept C11413529 @default.
- W2035999724 hasConcept C119599485 @default.
- W2035999724 hasConcept C126255220 @default.
- W2035999724 hasConcept C127413603 @default.
- W2035999724 hasConcept C138885662 @default.
- W2035999724 hasConcept C14036430 @default.
- W2035999724 hasConcept C147764199 @default.
- W2035999724 hasConcept C152769699 @default.
- W2035999724 hasConcept C185592680 @default.
- W2035999724 hasConcept C204328495 @default.
- W2035999724 hasConcept C26517878 @default.
- W2035999724 hasConcept C2776545253 @default.
- W2035999724 hasConcept C2776559745 @default.
- W2035999724 hasConcept C2778976237 @default.
- W2035999724 hasConcept C2780586882 @default.
- W2035999724 hasConcept C33923547 @default.
- W2035999724 hasConcept C38652104 @default.
- W2035999724 hasConcept C41008148 @default.
- W2035999724 hasConcept C47701112 @default.
- W2035999724 hasConcept C55493867 @default.
- W2035999724 hasConcept C67705224 @default.
- W2035999724 hasConcept C78458016 @default.
- W2035999724 hasConcept C86803240 @default.
- W2035999724 hasConcept C98045186 @default.
- W2035999724 hasConceptScore W2035999724C104317684 @default.
- W2035999724 hasConceptScore W2035999724C111472728 @default.
- W2035999724 hasConceptScore W2035999724C111919701 @default.