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- W2036008857 abstract "The activity of glucose-6-phosphate dehydrogenase in mouse liver increases up to 8-fold when young mice are shifted from a high-fat to a fatless diet. Similar changes are exhibited by fatty acid synthetase and 6-phosphogluconate dehydrogenase. The extent of induction decreases appreciably beyond 4 months of age and is only occasionally observed in animals beyond one year of age. In contrast, in animals continuously maintained with induced enzyme levels, repression to basal values takes place at all ages. The problem whether the loss of inducibility is related to body lipid accumulation or is due to a fundamental senescent process is discussed. The changes in activity of glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and fatty acid synthetase from birth through weaning to old age are described." @default.
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- W2036008857 title "The effect of age on the regulation of glucose-6-phosphate dehydragenase in mouse liver" @default.
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- W2036008857 doi "https://doi.org/10.1016/0531-5565(76)90015-2" @default.
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