FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036035532> ?p ?o ?g. }

• W2036035532 endingPage "917" @default.
• W2036035532 startingPage "908" @default.
• W2036035532 abstract "Individual tumor cells utilize one of two modes of motility to invade the extracellular matrix, mesenchymal or amoeboid. We have determined that the diterpenoid genkwanine M (GENK) enhances the mesenchymal mode of cell motility that is intrinsic to HT-1080 osteosarcoma cells, stimulates a mesenchymal mode of motility in stationary MDA-MB-453 breast carcinoma cells, and induces a shift to a mesenchymal mode of cell motility in LS174T colorectal adenocarcinoma cells that normally utilize the alternate amoeboid mode of motility. The ability of GENK to stimulate or induce mesenchymal motility was preceded by a rapid cell spreading, elongation and polarization that did not require new gene expression. However, these initial morphologic changes were integrin dependent and they were associated with a reorganization of focal contacts and focal adhesions as well as an activation of the focal adhesion kinase. Therefore, GENK induces a mesenchymal mode of cell motility in a wide variety of tumor cell types that may be mediated, at least in part, by an activation of integrin-associated signaling." @default.
• W2036035532 created "2016-06-24" @default.
• W2036035532 creator A5001658286 @default.
• W2036035532 creator A5017550183 @default.
• W2036035532 creator A5027610565 @default.
• W2036035532 creator A5032768593 @default.
• W2036035532 creator A5067322380 @default.
• W2036035532 creator A5075759028 @default.
• W2036035532 creator A5076684549 @default.
• W2036035532 creator A5081399869 @default.
• W2036035532 creator A5084792106 @default.
• W2036035532 creator A5087239481 @default.
• W2036035532 date "2013-04-01" @default.
• W2036035532 modified "2023-09-26" @default.
• W2036035532 title "The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility" @default.
• W2036035532 cites W1542536208 @default.
• W2036035532 cites W1970265228 @default.
• W2036035532 cites W1972028538 @default.
• W2036035532 cites W1980525108 @default.
• W2036035532 cites W1984483611 @default.
• W2036035532 cites W2009966082 @default.
• W2036035532 cites W2014424859 @default.
• W2036035532 cites W2016194889 @default.
• W2036035532 cites W2055720287 @default.
• W2036035532 cites W2083543572 @default.
• W2036035532 cites W2112013928 @default.
• W2036035532 cites W2113615565 @default.
• W2036035532 cites W2124393085 @default.
• W2036035532 cites W2129926378 @default.
• W2036035532 cites W2133054656 @default.
• W2036035532 cites W2139241071 @default.
• W2036035532 cites W2146177789 @default.
• W2036035532 cites W2149688672 @default.
• W2036035532 cites W2161842873 @default.
• W2036035532 cites W2162351740 @default.
• W2036035532 cites W2171179595 @default.
• W2036035532 cites W2951335522 @default.
• W2036035532 doi "https://doi.org/10.1016/j.yexcr.2013.01.005" @default.
• W2036035532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23333560" @default.
• W2036035532 hasPublicationYear "2013" @default.
• W2036035532 type Work @default.
• W2036035532 sameAs 2036035532 @default.
• W2036035532 citedByCount "0" @default.
• W2036035532 crossrefType "journal-article" @default.
• W2036035532 hasAuthorship W2036035532A5001658286 @default.
• W2036035532 hasAuthorship W2036035532A5017550183 @default.
• W2036035532 hasAuthorship W2036035532A5027610565 @default.
• W2036035532 hasAuthorship W2036035532A5032768593 @default.
• W2036035532 hasAuthorship W2036035532A5067322380 @default.
• W2036035532 hasAuthorship W2036035532A5075759028 @default.
• W2036035532 hasAuthorship W2036035532A5076684549 @default.
• W2036035532 hasAuthorship W2036035532A5081399869 @default.
• W2036035532 hasAuthorship W2036035532A5084792106 @default.
• W2036035532 hasAuthorship W2036035532A5087239481 @default.
• W2036035532 hasConcept C1491633281 @default.
• W2036035532 hasConcept C151166631 @default.
• W2036035532 hasConcept C16224149 @default.
• W2036035532 hasConcept C189165786 @default.
• W2036035532 hasConcept C195687474 @default.
• W2036035532 hasConcept C198826908 @default.
• W2036035532 hasConcept C55493867 @default.
• W2036035532 hasConcept C58207958 @default.
• W2036035532 hasConcept C62478195 @default.
• W2036035532 hasConcept C85789140 @default.
• W2036035532 hasConcept C86803240 @default.
• W2036035532 hasConcept C95444343 @default.
• W2036035532 hasConceptScore W2036035532C1491633281 @default.
• W2036035532 hasConceptScore W2036035532C151166631 @default.
• W2036035532 hasConceptScore W2036035532C16224149 @default.
• W2036035532 hasConceptScore W2036035532C189165786 @default.
• W2036035532 hasConceptScore W2036035532C195687474 @default.
• W2036035532 hasConceptScore W2036035532C198826908 @default.
• W2036035532 hasConceptScore W2036035532C55493867 @default.
• W2036035532 hasConceptScore W2036035532C58207958 @default.
• W2036035532 hasConceptScore W2036035532C62478195 @default.
• W2036035532 hasConceptScore W2036035532C85789140 @default.
• W2036035532 hasConceptScore W2036035532C86803240 @default.
• W2036035532 hasConceptScore W2036035532C95444343 @default.
• W2036035532 hasFunder F4320334506 @default.
• W2036035532 hasFunder F4320334576 @default.
• W2036035532 hasIssue "6" @default.
• W2036035532 hasLocation W20360355321 @default.
• W2036035532 hasLocation W20360355322 @default.
• W2036035532 hasOpenAccess W2036035532 @default.
• W2036035532 hasPrimaryLocation W20360355321 @default.
• W2036035532 hasRelatedWork W1601813195 @default.
• W2036035532 hasRelatedWork W1981551966 @default.
• W2036035532 hasRelatedWork W1986411839 @default.
• W2036035532 hasRelatedWork W2045377853 @default.
• W2036035532 hasRelatedWork W2084295528 @default.
• W2036035532 hasRelatedWork W2118891678 @default.
• W2036035532 hasRelatedWork W2159437476 @default.
• W2036035532 hasRelatedWork W2267747817 @default.
• W2036035532 hasRelatedWork W2527758949 @default.
• W2036035532 hasRelatedWork W4231274896 @default.
• W2036035532 hasVolume "319" @default.
• W2036035532 isParatext "false" @default.
• W2036035532 isRetracted "false" @default.

• next