Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036037848> ?p ?o ?g. }
- W2036037848 endingPage "455" @default.
- W2036037848 startingPage "442" @default.
- W2036037848 abstract "Gamma-linolenic acid (GLA) has been reported as a potential anti-cancer and anti-inflammatory agent and has received substantial attention in cancer care research. One of the many proposed mechanisms for GLA biological activity is free radical-mediated lipid peroxidation. However, no direct evidence has been obtained for the formation of GLA-derived radicals. In this study, a combination of LC/ESR and LC/MS was used with alpha-[4-pyridyl-1-oxide]-N-tert-butyl nitrone (POBN) to profile the carbon-centred radicals that are generated in lipoxygenase-catalysed GLA peroxidation. A total of four classes of GLA-derived radicals were characterized including GLA-alkyl, epoxyallylic, dihydroxyallylic radicals and a variety of carbon-centred radicals stemming from the beta-scissions of GLA-alkoxyl radicals. By means of an internal standard in LC/MS, one also quantified each radical adduct in all its redox forms, including an ESR-active form and two ESR-silent forms. The results provided a good starting point for ongoing research in defining the possible biological effects of radicals generated from GLA peroxidation." @default.
- W2036037848 created "2016-06-24" @default.
- W2036037848 creator A5004853365 @default.
- W2036037848 creator A5028110685 @default.
- W2036037848 creator A5028254997 @default.
- W2036037848 creator A5053201606 @default.
- W2036037848 date "2008-01-01" @default.
- W2036037848 modified "2023-10-16" @default.
- W2036037848 title "LC/ESR/MS study of spin trapped carbon-centred radicals formed from<i>in vitro</i>lipoxygenase-catalysed peroxidation of<i>γ</i>-linolenic acid" @default.
- W2036037848 cites W1561350880 @default.
- W2036037848 cites W1877788243 @default.
- W2036037848 cites W1964194977 @default.
- W2036037848 cites W1970221239 @default.
- W2036037848 cites W1973324444 @default.
- W2036037848 cites W1975978557 @default.
- W2036037848 cites W1978830767 @default.
- W2036037848 cites W1990285596 @default.
- W2036037848 cites W1997080726 @default.
- W2036037848 cites W1998048303 @default.
- W2036037848 cites W2013592393 @default.
- W2036037848 cites W2013596666 @default.
- W2036037848 cites W2022473652 @default.
- W2036037848 cites W2024921655 @default.
- W2036037848 cites W2035477746 @default.
- W2036037848 cites W2037727272 @default.
- W2036037848 cites W2038990764 @default.
- W2036037848 cites W2044779565 @default.
- W2036037848 cites W2045080266 @default.
- W2036037848 cites W2051257813 @default.
- W2036037848 cites W2052438063 @default.
- W2036037848 cites W2061288807 @default.
- W2036037848 cites W2062973904 @default.
- W2036037848 cites W2064496230 @default.
- W2036037848 cites W2071201086 @default.
- W2036037848 cites W2071267404 @default.
- W2036037848 cites W2074668577 @default.
- W2036037848 cites W2087964719 @default.
- W2036037848 cites W2091197275 @default.
- W2036037848 cites W2093920817 @default.
- W2036037848 cites W2126482058 @default.
- W2036037848 cites W2133946180 @default.
- W2036037848 cites W2144981646 @default.
- W2036037848 cites W2152340091 @default.
- W2036037848 cites W2159729794 @default.
- W2036037848 cites W4234604396 @default.
- W2036037848 cites W4237995007 @default.
- W2036037848 doi "https://doi.org/10.1080/10715760802085344" @default.
- W2036037848 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2722041" @default.
- W2036037848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18484409" @default.
- W2036037848 hasPublicationYear "2008" @default.
- W2036037848 type Work @default.
- W2036037848 sameAs 2036037848 @default.
- W2036037848 citedByCount "17" @default.
- W2036037848 countsByYear W20360378482012 @default.
- W2036037848 countsByYear W20360378482013 @default.
- W2036037848 countsByYear W20360378482015 @default.
- W2036037848 countsByYear W20360378482017 @default.
- W2036037848 countsByYear W20360378482018 @default.
- W2036037848 countsByYear W20360378482020 @default.
- W2036037848 countsByYear W20360378482021 @default.
- W2036037848 crossrefType "journal-article" @default.
- W2036037848 hasAuthorship W2036037848A5004853365 @default.
- W2036037848 hasAuthorship W2036037848A5028110685 @default.
- W2036037848 hasAuthorship W2036037848A5028254997 @default.
- W2036037848 hasAuthorship W2036037848A5053201606 @default.
- W2036037848 hasBestOaLocation W20360378482 @default.
- W2036037848 hasConcept C139066938 @default.
- W2036037848 hasConcept C181199279 @default.
- W2036037848 hasConcept C185592680 @default.
- W2036037848 hasConcept C2778004101 @default.
- W2036037848 hasConcept C2780829032 @default.
- W2036037848 hasConcept C2780857362 @default.
- W2036037848 hasConcept C55493867 @default.
- W2036037848 hasConcept C75473681 @default.
- W2036037848 hasConceptScore W2036037848C139066938 @default.
- W2036037848 hasConceptScore W2036037848C181199279 @default.
- W2036037848 hasConceptScore W2036037848C185592680 @default.
- W2036037848 hasConceptScore W2036037848C2778004101 @default.
- W2036037848 hasConceptScore W2036037848C2780829032 @default.
- W2036037848 hasConceptScore W2036037848C2780857362 @default.
- W2036037848 hasConceptScore W2036037848C55493867 @default.
- W2036037848 hasConceptScore W2036037848C75473681 @default.
- W2036037848 hasIssue "5" @default.
- W2036037848 hasLocation W20360378481 @default.
- W2036037848 hasLocation W20360378482 @default.
- W2036037848 hasLocation W20360378483 @default.
- W2036037848 hasLocation W20360378484 @default.
- W2036037848 hasOpenAccess W2036037848 @default.
- W2036037848 hasPrimaryLocation W20360378481 @default.
- W2036037848 hasRelatedWork W1969404129 @default.
- W2036037848 hasRelatedWork W1972947504 @default.
- W2036037848 hasRelatedWork W2036037848 @default.
- W2036037848 hasRelatedWork W2070937509 @default.
- W2036037848 hasRelatedWork W2080682147 @default.
- W2036037848 hasRelatedWork W2149906820 @default.
- W2036037848 hasRelatedWork W2164471494 @default.
- W2036037848 hasRelatedWork W2310272287 @default.
- W2036037848 hasRelatedWork W2384752203 @default.