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- W2036041743 abstract "The glycoside bond in alkylated nucleosides is known to be more stable for 06-alkylguanosines and O4-alkylthymines, and less stable for N3- and N7-alkylpurine and O2-alkylpyrimidine nucleosides. These marked differences have been demonstrated through in vitro acidic hydrolysis and in vivo glycosylase repair. This study examines the relative facility of the deglycosylation reaction for various nucleosides through the use of theoretical indices derived from the semiempirical AMI SCF-MO methodology, which furnish inferences much in consonance with experiment." @default.
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- W2036041743 date "1973-08-01" @default.
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- W2036041743 title "Reaction of N-methyl-N-nitrosourea (MNUA) with 32P-labelled DNA: evidence for formation of phosphotriesters" @default.
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- W2036041743 doi "https://doi.org/10.1016/0009-2797(73)90022-7" @default.
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