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- W2036046856 abstract "Inherited thrombophilias are associated with an increased risk of maternal thromboembolism and certain adverse pregnancy outcomes, including second- and third-trimester fetal loss, placental abruption, severe intrauterine growth restriction, and early-onset, severe preeclampsia. Pregnant patients with severe thrombophilias, especially antithrombinopathies are at very high risk for both thromboembolism and adverse pregnancy outcomes. A case of a patient with antithrombin deficiency is reported, who had two successful pregnancies after eight miscarriages. Our case shows that a combined treatment with antithrombin substitution and a prophylactic, body-weight-adjusted dose of low-molecular-weight heparin may be successful in preventing pregnancy loss and thromboembolism in antithrombin deficiency during pregnancy, although other complications, such as preeclampsia and intrauterine growth restriction cannot always be prevented." @default.
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- W2036046856 date "2006-01-01" @default.
- W2036046856 modified "2023-10-11" @default.
- W2036046856 title "Two Successful Pregnancies following Eight Miscarriages in a Patient with Antithrombin Deficiency" @default.
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- W2036046856 doi "https://doi.org/10.1159/000089159" @default.
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