Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036072927> ?p ?o ?g. }
- W2036072927 endingPage "1893" @default.
- W2036072927 startingPage "1890" @default.
- W2036072927 abstract "Interleukin 10 (IL-10), originally identified as a TH2 helper T-cell product able to inhibit cytokine production by TH1 cells, is highly homologous to BCRF1 (viral IL-10), an open reading frame in the Epstein-Barr virus genome. Here, we show that human and viral IL-10 stimulate DNA replication of B lymphocytes activated either via their antigen receptor or via their CD40 antigen. IL-4 and IL-10 display additive effects and induce a strong increase in the number of viable cells. Moreover, IL-10 induces activated B cells to secrete large amounts of IgG, IgA, and IgM, and the combination of IL-10 and IL-4 results in the secretion of the four immunoglobulin isotypes. Thus, IL-10 may play an important role in the amplification of humoral responses." @default.
- W2036072927 created "2016-06-24" @default.
- W2036072927 creator A5002962815 @default.
- W2036072927 creator A5007180038 @default.
- W2036072927 creator A5021333463 @default.
- W2036072927 creator A5021895713 @default.
- W2036072927 creator A5024476824 @default.
- W2036072927 creator A5041009675 @default.
- W2036072927 creator A5048916540 @default.
- W2036072927 creator A5072091155 @default.
- W2036072927 creator A5088336262 @default.
- W2036072927 date "1992-03-01" @default.
- W2036072927 modified "2023-10-14" @default.
- W2036072927 title "Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes." @default.
- W2036072927 cites W1512002142 @default.
- W2036072927 cites W1675487153 @default.
- W2036072927 cites W1853022482 @default.
- W2036072927 cites W1942668068 @default.
- W2036072927 cites W1959472468 @default.
- W2036072927 cites W1964435679 @default.
- W2036072927 cites W1981533854 @default.
- W2036072927 cites W1982647690 @default.
- W2036072927 cites W1989055057 @default.
- W2036072927 cites W1989692667 @default.
- W2036072927 cites W1991070341 @default.
- W2036072927 cites W2030265994 @default.
- W2036072927 cites W2037240183 @default.
- W2036072927 cites W2047999732 @default.
- W2036072927 cites W2050583442 @default.
- W2036072927 cites W2055336483 @default.
- W2036072927 cites W2058050336 @default.
- W2036072927 cites W2060546545 @default.
- W2036072927 cites W2084990572 @default.
- W2036072927 cites W2091152189 @default.
- W2036072927 cites W2095343750 @default.
- W2036072927 cites W2120012263 @default.
- W2036072927 cites W2165644577 @default.
- W2036072927 cites W2172466148 @default.
- W2036072927 doi "https://doi.org/10.1073/pnas.89.5.1890" @default.
- W2036072927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/48559" @default.
- W2036072927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1371884" @default.
- W2036072927 hasPublicationYear "1992" @default.
- W2036072927 type Work @default.
- W2036072927 sameAs 2036072927 @default.
- W2036072927 citedByCount "1170" @default.
- W2036072927 countsByYear W20360729272012 @default.
- W2036072927 countsByYear W20360729272013 @default.
- W2036072927 countsByYear W20360729272014 @default.
- W2036072927 countsByYear W20360729272015 @default.
- W2036072927 countsByYear W20360729272016 @default.
- W2036072927 countsByYear W20360729272017 @default.
- W2036072927 countsByYear W20360729272018 @default.
- W2036072927 countsByYear W20360729272019 @default.
- W2036072927 countsByYear W20360729272020 @default.
- W2036072927 countsByYear W20360729272021 @default.
- W2036072927 countsByYear W20360729272022 @default.
- W2036072927 countsByYear W20360729272023 @default.
- W2036072927 crossrefType "journal-article" @default.
- W2036072927 hasAuthorship W2036072927A5002962815 @default.
- W2036072927 hasAuthorship W2036072927A5007180038 @default.
- W2036072927 hasAuthorship W2036072927A5021333463 @default.
- W2036072927 hasAuthorship W2036072927A5021895713 @default.
- W2036072927 hasAuthorship W2036072927A5024476824 @default.
- W2036072927 hasAuthorship W2036072927A5041009675 @default.
- W2036072927 hasAuthorship W2036072927A5048916540 @default.
- W2036072927 hasAuthorship W2036072927A5072091155 @default.
- W2036072927 hasAuthorship W2036072927A5088336262 @default.
- W2036072927 hasBestOaLocation W20360729272 @default.
- W2036072927 hasConcept C147483822 @default.
- W2036072927 hasConcept C153911025 @default.
- W2036072927 hasConcept C154317977 @default.
- W2036072927 hasConcept C159654299 @default.
- W2036072927 hasConcept C202751555 @default.
- W2036072927 hasConcept C203014093 @default.
- W2036072927 hasConcept C2778690821 @default.
- W2036072927 hasConcept C39347974 @default.
- W2036072927 hasConcept C49039625 @default.
- W2036072927 hasConcept C55493867 @default.
- W2036072927 hasConcept C86803240 @default.
- W2036072927 hasConceptScore W2036072927C147483822 @default.
- W2036072927 hasConceptScore W2036072927C153911025 @default.
- W2036072927 hasConceptScore W2036072927C154317977 @default.
- W2036072927 hasConceptScore W2036072927C159654299 @default.
- W2036072927 hasConceptScore W2036072927C202751555 @default.
- W2036072927 hasConceptScore W2036072927C203014093 @default.
- W2036072927 hasConceptScore W2036072927C2778690821 @default.
- W2036072927 hasConceptScore W2036072927C39347974 @default.
- W2036072927 hasConceptScore W2036072927C49039625 @default.
- W2036072927 hasConceptScore W2036072927C55493867 @default.
- W2036072927 hasConceptScore W2036072927C86803240 @default.
- W2036072927 hasIssue "5" @default.
- W2036072927 hasLocation W20360729271 @default.
- W2036072927 hasLocation W20360729272 @default.
- W2036072927 hasLocation W20360729273 @default.
- W2036072927 hasLocation W20360729274 @default.
- W2036072927 hasOpenAccess W2036072927 @default.
- W2036072927 hasPrimaryLocation W20360729271 @default.
- W2036072927 hasRelatedWork W1497833379 @default.