Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036077752> ?p ?o ?g. }
- W2036077752 endingPage "873" @default.
- W2036077752 startingPage "873" @default.
- W2036077752 abstract "To characterize the static blood flow autoregulation in the optic nerve head (ONH), and to investigate its role in hemodynamic changes in experimental glaucoma (EG).Unilateral elevation of intraocular pressure (IOP) was induced in 15 adult rhesus macaques by laser treatment to the trabecular meshwork. Prior to and after laser treatment, retinal nerve fiber layer thickness (RNFLT) was assessed, biweekly, by spectral-domain optical coherence tomography. Optic nerve head static autoregulation was assessed by determining the percentage blood flow (BF) change after the IOP was acutely increased from 10 to 30, 40, or 50 mm Hg manometrically, utilizing a laser speckle flowgraphy device.Postlaser IOP (measured during average 7.7 ± 2.6 months) was 20.2 ± 5.9 mm Hg in EG eyes and 12.3 ± 2.6 mm Hg in control eyes (P < 0.0001). Retinal nerve fiber layer thickness was reduced by 33 ± 22% of the baseline values (P < 0.001) on average in EG eyes and by 0.4 ± 2.3% in control eyes (P > 0.05). The ONH BF remained at a constant level within a range of ocular perfusion pressure (OPP), 41 mm Hg and above. The autoregulation curves, created by all 723 tests in control and 352 tests in EG, were not significantly different (P = 0.71).Optic nerve head BF in normal nonhuman primate (NHP) eyes is effectively regulated within a range of OPP approximately 41 mm Hg and above. Chronic IOP elevation causes no remarkable change to the static autoregulation within the ONH of EG eyes." @default.
- W2036077752 created "2016-06-24" @default.
- W2036077752 creator A5011220438 @default.
- W2036077752 creator A5032073359 @default.
- W2036077752 creator A5033957225 @default.
- W2036077752 creator A5035431800 @default.
- W2036077752 creator A5076453527 @default.
- W2036077752 date "2014-02-10" @default.
- W2036077752 modified "2023-10-16" @default.
- W2036077752 title "Static Blood Flow Autoregulation in the Optic Nerve Head in Normal and Experimental Glaucoma" @default.
- W2036077752 cites W153914050 @default.
- W2036077752 cites W1568617780 @default.
- W2036077752 cites W1820993272 @default.
- W2036077752 cites W186909258 @default.
- W2036077752 cites W1926645814 @default.
- W2036077752 cites W1965464815 @default.
- W2036077752 cites W1968360214 @default.
- W2036077752 cites W1969824248 @default.
- W2036077752 cites W1971946299 @default.
- W2036077752 cites W1972947450 @default.
- W2036077752 cites W1975361674 @default.
- W2036077752 cites W1981900389 @default.
- W2036077752 cites W1983292111 @default.
- W2036077752 cites W1991042974 @default.
- W2036077752 cites W2001005817 @default.
- W2036077752 cites W2002424474 @default.
- W2036077752 cites W2005657614 @default.
- W2036077752 cites W2006486224 @default.
- W2036077752 cites W2015371501 @default.
- W2036077752 cites W2016083277 @default.
- W2036077752 cites W2016409092 @default.
- W2036077752 cites W2018241900 @default.
- W2036077752 cites W2020880765 @default.
- W2036077752 cites W2021199278 @default.
- W2036077752 cites W2021457050 @default.
- W2036077752 cites W2022372377 @default.
- W2036077752 cites W2022805799 @default.
- W2036077752 cites W2024376451 @default.
- W2036077752 cites W2030071875 @default.
- W2036077752 cites W2031895914 @default.
- W2036077752 cites W2032930138 @default.
- W2036077752 cites W2037011595 @default.
- W2036077752 cites W2044094512 @default.
- W2036077752 cites W2047496403 @default.
- W2036077752 cites W2047922146 @default.
- W2036077752 cites W2048830691 @default.
- W2036077752 cites W2052453633 @default.
- W2036077752 cites W2063057133 @default.
- W2036077752 cites W2067456914 @default.
- W2036077752 cites W2069426766 @default.
- W2036077752 cites W2070214399 @default.
- W2036077752 cites W2076061064 @default.
- W2036077752 cites W2076263308 @default.
- W2036077752 cites W2083592241 @default.
- W2036077752 cites W2087667808 @default.
- W2036077752 cites W2088905867 @default.
- W2036077752 cites W2090323725 @default.
- W2036077752 cites W2092433290 @default.
- W2036077752 cites W2095118245 @default.
- W2036077752 cites W2095817293 @default.
- W2036077752 cites W2100436846 @default.
- W2036077752 cites W2109543823 @default.
- W2036077752 cites W2136576129 @default.
- W2036077752 cites W2140718017 @default.
- W2036077752 cites W2144055574 @default.
- W2036077752 cites W2151590992 @default.
- W2036077752 cites W2152935893 @default.
- W2036077752 cites W2166685147 @default.
- W2036077752 cites W2166740195 @default.
- W2036077752 cites W2295600458 @default.
- W2036077752 cites W2312644419 @default.
- W2036077752 cites W2323311554 @default.
- W2036077752 cites W2415247585 @default.
- W2036077752 cites W31332176 @default.
- W2036077752 cites W3168008081 @default.
- W2036077752 cites W3202493352 @default.
- W2036077752 doi "https://doi.org/10.1167/iovs.13-13716" @default.
- W2036077752 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3920822" @default.
- W2036077752 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24436190" @default.
- W2036077752 hasPublicationYear "2014" @default.
- W2036077752 type Work @default.
- W2036077752 sameAs 2036077752 @default.
- W2036077752 citedByCount "31" @default.
- W2036077752 countsByYear W20360777522014 @default.
- W2036077752 countsByYear W20360777522015 @default.
- W2036077752 countsByYear W20360777522016 @default.
- W2036077752 countsByYear W20360777522017 @default.
- W2036077752 countsByYear W20360777522018 @default.
- W2036077752 countsByYear W20360777522019 @default.
- W2036077752 countsByYear W20360777522021 @default.
- W2036077752 countsByYear W20360777522022 @default.
- W2036077752 countsByYear W20360777522023 @default.
- W2036077752 crossrefType "journal-article" @default.
- W2036077752 hasAuthorship W2036077752A5011220438 @default.
- W2036077752 hasAuthorship W2036077752A5032073359 @default.
- W2036077752 hasAuthorship W2036077752A5033957225 @default.
- W2036077752 hasAuthorship W2036077752A5035431800 @default.
- W2036077752 hasAuthorship W2036077752A5076453527 @default.