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• W2036084985 abstract "A novel form of receptor-kinase interaction was first described in the interaction between the CD4 and CD8 antigens and the protein-tyrosine kinase p56lck. This linkage, between a regulatory antigen on T cells and a member of a family of intracellular molecules with an established ability to activate and transform cells, is likely to be of great importance in the regulation of T-cell growth. Recently, data have been obtained on the molecular basis of regulation of the CD4/CD8-p56lck interaction and an interaction between the T-cell receptor complex (TCR-CD3) and another src-kinase p59fyn has been described. Here, Christopher Rudd examines these interactions and outlines their potential roles in normal and malignant T-cell growth." @default.
• W2036084985 created "2016-06-24" @default.
• W2036084985 creator A5068202982 @default.
• W2036084985 date "1990-01-01" @default.
• W2036084985 modified "2023-09-25" @default.
• W2036084985 title "CD4, CD8 and the TCR-CD3 complex: a novel class of protein-tyrosine kinase receptor" @default.
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• W2036084985 doi "https://doi.org/10.1016/0167-5699(90)90159-7" @default.
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