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- W2036106004 abstract "A man aged 19 years, previously in good health with no history of febrile convulsions or head injury or family history of diabetes or other autoimmune disorders, suddenly developed complex partial seizures. The episodes occurred several times a day over the next 4 months. Routine blood analyses and neurological assessments were normal. Electro-encephalography showed temporal and parietal spikes, and signal abnormalities were seen on magnetic-resonance images. Analysis of cerebrospinal fluid showed mild lymphocytic pleiocytosis (25/mm 3 Giometto B Miotto D Faresin F Argentiero V Scaravilli T Tavolato B Anti-GABAergic neuron autoantibodies in a patient with stiff-man syndrome and ataxia. J Neurol Sci. 1996; 143: 57-59 Summary Full Text Full Text PDF PubMed Scopus (55) Google Scholar ), increased IgG intrathecal synthesis (IgG index 0·8; normal <0·7) and IgG oligoclonal bands, which confirmed acute encephalitis. PCR analysis for herpesvirus and antibodies, and antibodies to Epstein-Barr virus and to cytomegalovirus were negative in the serum and cerebrospinal fluid. Thoracic and abdominal computed-tomography scans did not show tumours at 1 year follow-up. Multiple antiepileptic drugs were tried with no success, but transient remission (2 weeks) was obtained with methylprednisolone (1 g daily for 5 days)." @default.
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- W2036106004 date "1998-08-01" @default.
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- W2036106004 title "Temporal-lobe epilepsy associated with glutamic-acid-decarboxylase autoantibodies" @default.
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- W2036106004 doi "https://doi.org/10.1016/s0140-6736(05)79192-3" @default.
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