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• W2036133091 abstract "The results of clinical trials investigating various therapies in acute ischemic stroke have been inconsistent. The effect of glycerol therapy and a combination therapy of glycerol and dextran was evaluated in a double-blind, placebo-controlled study. Repeated neurologic examinations (Day 0, Weeks 1, 6, 12, and 24) according to a modified Mathew score were performed on 62 patients. Statistical analysis showed no superiority of either treatment compared with placebo in acute ischemic stroke. A retrospective estimation of the Type II error of the study yielded approximately p = 0.25. A major side effect was hemolysis in 98% of patients treated with glycerol." @default.
• W2036133091 created "2016-06-24" @default.
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• W2036133091 date "1987-03-01" @default.
• W2036133091 modified "2023-09-27" @default.
• W2036133091 title "Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis." @default.
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• W2036133091 doi "https://doi.org/10.1161/01.str.18.2.373" @default.
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