FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036134969> ?p ?o ?g. }

• W2036134969 endingPage "248" @default.
• W2036134969 startingPage "244" @default.
• W2036134969 abstract "Cerebrospinal fluid (CSF) is an ideal biological material in which to search for new biomarkers for improved diagnosis of neurological diseases. During a lumbar puncture between 5 and 15 mL of CSF are obtained. Previous studies have assessed the ventriculo-lumbar concentration gradient of a number of specific proteins. In the present study we took a proteomics approach to investigate the possible concentration gradient of a panel of proteins and peptides in the CSF of 16 patients with neurodegenerative diseases. Using two different mass spectrometry techniques, matrix assisted laser desorption ionization time of flight (MALDI-TOF) and surface enhanced laser desorption ionization time of flight (SELDI-TOF), we found that only one of the investigated proteins, apolipoprotein CI, was significantly decreased between the 1st and the 10th mL of CSF. Furthermore, we confirmed previous results showing a significant decrease in albumin concentration from the first to the last CSF aliquots. In conclusion, we found a significant gradient effect for only two of the measured proteins. However, a standardized procedure for CSF collection for diagnostic and research purposes is crucial to allow comparisons of results between patient groups and between laboratories. This is especially important since CSF is usually collected at several centres and variation in sampled CSF due to pre-analytical factors could complicate the interpretation of the results." @default.
• W2036134969 created "2016-06-24" @default.
• W2036134969 creator A5008932144 @default.
• W2036134969 creator A5015557380 @default.
• W2036134969 creator A5016536007 @default.
• W2036134969 creator A5017624827 @default.
• W2036134969 creator A5018979310 @default.
• W2036134969 creator A5058081634 @default.
• W2036134969 creator A5061381597 @default.
• W2036134969 creator A5073060613 @default.
• W2036134969 creator A5078222323 @default.
• W2036134969 creator A5080864601 @default.
• W2036134969 date "2010-08-01" @default.
• W2036134969 modified "2023-10-03" @default.
• W2036134969 title "Proteomic investigations of the ventriculo-lumbar gradient in human CSF" @default.
• W2036134969 cites W1526510085 @default.
• W2036134969 cites W1898042710 @default.
• W2036134969 cites W1915023557 @default.
• W2036134969 cites W1990190807 @default.
• W2036134969 cites W1994723621 @default.
• W2036134969 cites W2002387090 @default.
• W2036134969 cites W2005893148 @default.
• W2036134969 cites W2008126460 @default.
• W2036134969 cites W2018738024 @default.
• W2036134969 cites W2042085383 @default.
• W2036134969 cites W2061866146 @default.
• W2036134969 cites W2079048613 @default.
• W2036134969 cites W2079370736 @default.
• W2036134969 cites W2081730310 @default.
• W2036134969 cites W2087976728 @default.
• W2036134969 cites W2128244416 @default.
• W2036134969 cites W2133566346 @default.
• W2036134969 cites W2162637834 @default.
• W2036134969 cites W2755169970 @default.
• W2036134969 doi "https://doi.org/10.1016/j.jneumeth.2010.06.017" @default.
• W2036134969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20599557" @default.
• W2036134969 hasPublicationYear "2010" @default.
• W2036134969 type Work @default.
• W2036134969 sameAs 2036134969 @default.
• W2036134969 citedByCount "19" @default.
• W2036134969 countsByYear W20361349692012 @default.
• W2036134969 countsByYear W20361349692013 @default.
• W2036134969 countsByYear W20361349692014 @default.
• W2036134969 countsByYear W20361349692015 @default.
• W2036134969 countsByYear W20361349692019 @default.
• W2036134969 countsByYear W20361349692020 @default.
• W2036134969 countsByYear W20361349692021 @default.
• W2036134969 countsByYear W20361349692022 @default.
• W2036134969 countsByYear W20361349692023 @default.
• W2036134969 crossrefType "journal-article" @default.
• W2036134969 hasAuthorship W2036134969A5008932144 @default.
• W2036134969 hasAuthorship W2036134969A5015557380 @default.
• W2036134969 hasAuthorship W2036134969A5016536007 @default.
• W2036134969 hasAuthorship W2036134969A5017624827 @default.
• W2036134969 hasAuthorship W2036134969A5018979310 @default.
• W2036134969 hasAuthorship W2036134969A5058081634 @default.
• W2036134969 hasAuthorship W2036134969A5061381597 @default.
• W2036134969 hasAuthorship W2036134969A5073060613 @default.
• W2036134969 hasAuthorship W2036134969A5078222323 @default.
• W2036134969 hasAuthorship W2036134969A5080864601 @default.
• W2036134969 hasConcept C104317684 @default.
• W2036134969 hasConcept C142724271 @default.
• W2036134969 hasConcept C146543888 @default.
• W2036134969 hasConcept C162356407 @default.
• W2036134969 hasConcept C185592680 @default.
• W2036134969 hasConcept C2776125364 @default.
• W2036134969 hasConcept C2779651940 @default.
• W2036134969 hasConcept C2780066322 @default.
• W2036134969 hasConcept C2910055489 @default.
• W2036134969 hasConcept C33619753 @default.
• W2036134969 hasConcept C43617362 @default.
• W2036134969 hasConcept C46111723 @default.
• W2036134969 hasConcept C55493867 @default.
• W2036134969 hasConcept C71924100 @default.
• W2036134969 hasConceptScore W2036134969C104317684 @default.
• W2036134969 hasConceptScore W2036134969C142724271 @default.
• W2036134969 hasConceptScore W2036134969C146543888 @default.
• W2036134969 hasConceptScore W2036134969C162356407 @default.
• W2036134969 hasConceptScore W2036134969C185592680 @default.
• W2036134969 hasConceptScore W2036134969C2776125364 @default.
• W2036134969 hasConceptScore W2036134969C2779651940 @default.
• W2036134969 hasConceptScore W2036134969C2780066322 @default.
• W2036134969 hasConceptScore W2036134969C2910055489 @default.
• W2036134969 hasConceptScore W2036134969C33619753 @default.
• W2036134969 hasConceptScore W2036134969C43617362 @default.
• W2036134969 hasConceptScore W2036134969C46111723 @default.
• W2036134969 hasConceptScore W2036134969C55493867 @default.
• W2036134969 hasConceptScore W2036134969C71924100 @default.
• W2036134969 hasIssue "2" @default.
• W2036134969 hasLocation W20361349691 @default.
• W2036134969 hasLocation W20361349692 @default.
• W2036134969 hasOpenAccess W2036134969 @default.
• W2036134969 hasPrimaryLocation W20361349691 @default.
• W2036134969 hasRelatedWork W2002387090 @default.
• W2036134969 hasRelatedWork W2004447662 @default.
• W2036134969 hasRelatedWork W2011773602 @default.
• W2036134969 hasRelatedWork W2035344757 @default.
• W2036134969 hasRelatedWork W2036134969 @default.

• next