Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036151693> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2036151693 endingPage "1338" @default.
- W2036151693 startingPage "1332" @default.
- W2036151693 abstract "The role of normocapnic hypoxemia (arterial PO2 33 +/- 7 torr for 30 minutes) in asphyxial renal failure and its modification by maturation of renal function was studied in 50 chronically catheterized, unanesthetized lambs of 2-38 days postnatal age. Arterial pH and PCO2 did not change significantly in response to hypoxemia in these lambs. Normocapnic hypoxemia was associated with (1) significant percent increases in arterial serum osmolality (1.82 +/- 2.96%, P = 0.0001), arterial blood lactate concentration (1009 +/- 2092%, P = 0.0018), arterial blood hematocrit (6 +/- 12%, P = 0.0016), arterial hemoglobin concentration (4.6 +/- 6.5%, P = 0.0004), arterial plasma vasopressin (2370 +/- 3340%, P = 0.0001), arterial plasma renin activity (153 +/- 230%, P = 0.0001), arterial plasma aldosterone (91.3 +/- 143%, P = 0.0001), and fractional sodium excretion rate (120 +/- 240%, P = 0.007); and (2) significant percent decline in glomerular filtration rate (-22.6 +/- 32.6%, P = 0.0003). Several responses to hypoxemia correlated significantly with postnatal age, including (1) positive correlation of postnatal age with percent change in blood osmolality (r = 0.36, P = 0.010), hematocrit (r = 0.48, P = 0.0005), hemoglobin (r = 0.59, P = 0.0004), and lactate (r = 0.72, P = 0.0001), suggesting greater water movement from the intravascular compartment in response to hypoxemia in more mature lambs; and (2) positive correlation of postnatal age with change in urinary flow rate (r = 0.66, P = 0.0001), urinary sodium excretion rate (r = 0.65, P = 0.0001), and osmolar clearance rate (r = 0.60, P = 0.0002), suggesting a greater effect of hypoxemia on the renal tubules to decrease sodium reabsorption in more mature kidneys. Thus, normocapnic hypoxemia may play a role in asphyxial renal failure, and the immature kidney does not have increased susceptibility to this condition." @default.
- W2036151693 created "2016-06-24" @default.
- W2036151693 creator A5057930855 @default.
- W2036151693 creator A5082163132 @default.
- W2036151693 date "1981-12-01" @default.
- W2036151693 modified "2023-09-27" @default.
- W2036151693 title "Postnatal age-related renal responses to hypoxemia in lambs." @default.
- W2036151693 cites W1634775066 @default.
- W2036151693 cites W1970993058 @default.
- W2036151693 cites W1973709780 @default.
- W2036151693 cites W1975622210 @default.
- W2036151693 cites W2004718047 @default.
- W2036151693 cites W2020991342 @default.
- W2036151693 cites W2068085519 @default.
- W2036151693 cites W2070483306 @default.
- W2036151693 cites W2084204774 @default.
- W2036151693 cites W2094244434 @default.
- W2036151693 cites W2130969262 @default.
- W2036151693 cites W4300787683 @default.
- W2036151693 doi "https://doi.org/10.1161/01.res.49.6.1332" @default.
- W2036151693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7307247" @default.
- W2036151693 hasPublicationYear "1981" @default.
- W2036151693 type Work @default.
- W2036151693 sameAs 2036151693 @default.
- W2036151693 citedByCount "12" @default.
- W2036151693 crossrefType "journal-article" @default.
- W2036151693 hasAuthorship W2036151693A5057930855 @default.
- W2036151693 hasAuthorship W2036151693A5082163132 @default.
- W2036151693 hasBestOaLocation W20361516931 @default.
- W2036151693 hasConcept C126322002 @default.
- W2036151693 hasConcept C134018914 @default.
- W2036151693 hasConcept C138976137 @default.
- W2036151693 hasConcept C142225936 @default.
- W2036151693 hasConcept C159641895 @default.
- W2036151693 hasConcept C198710026 @default.
- W2036151693 hasConcept C2776779939 @default.
- W2036151693 hasConcept C2777140959 @default.
- W2036151693 hasConcept C2778917026 @default.
- W2036151693 hasConcept C2779537118 @default.
- W2036151693 hasConcept C2780959883 @default.
- W2036151693 hasConcept C71924100 @default.
- W2036151693 hasConcept C84393581 @default.
- W2036151693 hasConceptScore W2036151693C126322002 @default.
- W2036151693 hasConceptScore W2036151693C134018914 @default.
- W2036151693 hasConceptScore W2036151693C138976137 @default.
- W2036151693 hasConceptScore W2036151693C142225936 @default.
- W2036151693 hasConceptScore W2036151693C159641895 @default.
- W2036151693 hasConceptScore W2036151693C198710026 @default.
- W2036151693 hasConceptScore W2036151693C2776779939 @default.
- W2036151693 hasConceptScore W2036151693C2777140959 @default.
- W2036151693 hasConceptScore W2036151693C2778917026 @default.
- W2036151693 hasConceptScore W2036151693C2779537118 @default.
- W2036151693 hasConceptScore W2036151693C2780959883 @default.
- W2036151693 hasConceptScore W2036151693C71924100 @default.
- W2036151693 hasConceptScore W2036151693C84393581 @default.
- W2036151693 hasIssue "6" @default.
- W2036151693 hasLocation W20361516931 @default.
- W2036151693 hasLocation W20361516932 @default.
- W2036151693 hasOpenAccess W2036151693 @default.
- W2036151693 hasPrimaryLocation W20361516931 @default.
- W2036151693 hasRelatedWork W1480749287 @default.
- W2036151693 hasRelatedWork W1966234050 @default.
- W2036151693 hasRelatedWork W1983853861 @default.
- W2036151693 hasRelatedWork W2031633633 @default.
- W2036151693 hasRelatedWork W2036151693 @default.
- W2036151693 hasRelatedWork W2099565451 @default.
- W2036151693 hasRelatedWork W2275109437 @default.
- W2036151693 hasRelatedWork W2283093578 @default.
- W2036151693 hasRelatedWork W3149240983 @default.
- W2036151693 hasRelatedWork W3150798040 @default.
- W2036151693 hasVolume "49" @default.
- W2036151693 isParatext "false" @default.
- W2036151693 isRetracted "false" @default.
- W2036151693 magId "2036151693" @default.
- W2036151693 workType "article" @default.