FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036187245> ?p ?o ?g. }

• W2036187245 endingPage "115" @default.
• W2036187245 startingPage "111" @default.
• W2036187245 abstract "Background Acute coronary syndrome (ACS) along with myocardial ischemic injury are the leading causes for chest pain. Platelet surface expression of stromal-cell-derived factor-1 (SDF-1) is enhanced during ischemic events and may play an important role in trafficking hematopoietic progenitor cells for tissue regeneration and neovascularization. This study examined the platelet surface expression of SDF-1 in patients with chest pain. Methods We consecutively evaluated 1000 patients, who were admitted to the emergency department with chest pain. Platelet surface expression of GPIb and SDF-1 was determined by two-color whole blood flow cytometry. Results Patients with ACS showed significantly enhanced SDF-1 expression on admission compared to patients with other causes such as stable angina pectoris (SAP) and other origin of chest pain (CPO) (ACS vs. SAP/CPO (mean fluorescence intensity (MFI)±SD): 39.7±26.3 vs. SAP: 37.6±31.5;P=0.045; arterial hypertension: 27.3±12.7;P=0.003; orthopedic disease: 22.1±6.5;P=0.014; pulmonary embolism: 26.6±19.1;P=0.003; Da Costa's syndrome: 22.1±12.5;P=0.021; inflammatory cardiomyopathy: 19.8±11.5;P=0.025). Logistic regression analysis showed that surface expression of platelet SDF-1 was significantly associated with ACS (P=0.026), however, the superiority of troponin-I in predicting ACS remains on a high level (P=0.001). Areas under the curve of receiver operating characteristic analysis revealed 0.718 (95% confidence interval (CI):0.680-0.757) using SDF-1, and 0.795 (95%CI:0.760-0.829) applying troponin-I baseline serum levels. Patients with enhanced SDF-1 levels (cutoff:MFI≥27.7) had a 1.4-fold relative risk (95%CI:1.17-1.52) for ACS. Conclusions Platelet SDF-1 surface expression was significantly enhanced in patients with ACS compared to SAP or CPO. Determination of platelet SDF-1 may be useful as an early additional biomarker for cardiovascular risk stratification." @default.
• W2036187245 created "2016-06-24" @default.
• W2036187245 creator A5008124856 @default.
• W2036187245 creator A5009135409 @default.
• W2036187245 creator A5023178909 @default.
• W2036187245 creator A5037492115 @default.
• W2036187245 creator A5039854847 @default.
• W2036187245 creator A5045291821 @default.
• W2036187245 creator A5047922322 @default.
• W2036187245 creator A5067454034 @default.
• W2036187245 creator A5078720904 @default.
• W2036187245 creator A5079002169 @default.
• W2036187245 creator A5081342175 @default.
• W2036187245 creator A5090714953 @default.
• W2036187245 date "2013-03-01" @default.
• W2036187245 modified "2023-10-17" @default.
• W2036187245 title "Platelet expression of stromal-cell-derived factor-1 (SDF-1): An indicator for ACS?" @default.
• W2036187245 cites W1561189761 @default.
• W2036187245 cites W1984915109 @default.
• W2036187245 cites W2010638326 @default.
• W2036187245 cites W2013627255 @default.
• W2036187245 cites W2015689066 @default.
• W2036187245 cites W2023198638 @default.
• W2036187245 cites W2039163665 @default.
• W2036187245 cites W2039881470 @default.
• W2036187245 cites W2058217708 @default.
• W2036187245 cites W2058806710 @default.
• W2036187245 cites W2073358241 @default.
• W2036187245 cites W2075972250 @default.
• W2036187245 cites W2087120448 @default.
• W2036187245 cites W2092635449 @default.
• W2036187245 cites W2096336546 @default.
• W2036187245 cites W2098636563 @default.
• W2036187245 cites W2106415952 @default.
• W2036187245 cites W2108875285 @default.
• W2036187245 cites W2117412164 @default.
• W2036187245 cites W2123973590 @default.
• W2036187245 cites W2129425642 @default.
• W2036187245 cites W2133496200 @default.
• W2036187245 cites W2143779041 @default.
• W2036187245 cites W2147824519 @default.
• W2036187245 cites W2150142996 @default.
• W2036187245 cites W2151945272 @default.
• W2036187245 cites W2161255846 @default.
• W2036187245 cites W2161579754 @default.
• W2036187245 cites W2166028130 @default.
• W2036187245 cites W2167808586 @default.
• W2036187245 cites W2169916808 @default.
• W2036187245 cites W2316599968 @default.
• W2036187245 cites W241141180 @default.
• W2036187245 cites W2611749980 @default.
• W2036187245 cites W2912662387 @default.
• W2036187245 cites W4213156194 @default.
• W2036187245 doi "https://doi.org/10.1016/j.ijcard.2011.06.082" @default.
• W2036187245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21737155" @default.
• W2036187245 hasPublicationYear "2013" @default.
• W2036187245 type Work @default.
• W2036187245 sameAs 2036187245 @default.
• W2036187245 citedByCount "26" @default.
• W2036187245 countsByYear W20361872452013 @default.
• W2036187245 countsByYear W20361872452014 @default.
• W2036187245 countsByYear W20361872452015 @default.
• W2036187245 countsByYear W20361872452016 @default.
• W2036187245 countsByYear W20361872452017 @default.
• W2036187245 countsByYear W20361872452018 @default.
• W2036187245 countsByYear W20361872452019 @default.
• W2036187245 countsByYear W20361872452021 @default.
• W2036187245 countsByYear W20361872452022 @default.
• W2036187245 crossrefType "journal-article" @default.
• W2036187245 hasAuthorship W2036187245A5008124856 @default.
• W2036187245 hasAuthorship W2036187245A5009135409 @default.
• W2036187245 hasAuthorship W2036187245A5023178909 @default.
• W2036187245 hasAuthorship W2036187245A5037492115 @default.
• W2036187245 hasAuthorship W2036187245A5039854847 @default.
• W2036187245 hasAuthorship W2036187245A5045291821 @default.
• W2036187245 hasAuthorship W2036187245A5047922322 @default.
• W2036187245 hasAuthorship W2036187245A5067454034 @default.
• W2036187245 hasAuthorship W2036187245A5078720904 @default.
• W2036187245 hasAuthorship W2036187245A5079002169 @default.
• W2036187245 hasAuthorship W2036187245A5081342175 @default.
• W2036187245 hasAuthorship W2036187245A5090714953 @default.
• W2036187245 hasConcept C126322002 @default.
• W2036187245 hasConcept C129470790 @default.
• W2036187245 hasConcept C13373296 @default.
• W2036187245 hasConcept C164705383 @default.
• W2036187245 hasConcept C2776610909 @default.
• W2036187245 hasConcept C2776914184 @default.
• W2036187245 hasConcept C2777698277 @default.
• W2036187245 hasConcept C2778213512 @default.
• W2036187245 hasConcept C2778704086 @default.
• W2036187245 hasConcept C3018697912 @default.
• W2036187245 hasConcept C500558357 @default.
• W2036187245 hasConcept C71924100 @default.
• W2036187245 hasConcept C89560881 @default.
• W2036187245 hasConcept C90924648 @default.
• W2036187245 hasConceptScore W2036187245C126322002 @default.
• W2036187245 hasConceptScore W2036187245C129470790 @default.
• W2036187245 hasConceptScore W2036187245C13373296 @default.

• next