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- W2036207428 abstract "Adrenals from 12-hr, 4 1/2, 7 1/2, 10-, and 14-day-old rats were used in this study. At 12 hr the cells of the zonae glomerulosa and fasciculata were similar to those of the adult adrenal cortex. The zona juxtamedullaris cells presented round mitochondria with vesicular cristae and very dense matrix and a large endoplasmic reticulum. After this age and until the 14th day, changes were slight and mainly regarding the size of cytoplasmic organelles. Variations in volumetric and surface densities were determined by stereological methods. These showed between 12 hr and 4 1/2 days of life in the three cortex zones a significant decrease of the volumetric densities of mitochondria (except the zona juxtamedullaris) and the endoplasmic reticulum (except in the zona glomerulosa) and a significant increase in the relative volume of the lipid droplets. The surface density of mitochondria decreased in the three zones, and the same parameter for the lipid droplets significantly increased in the zonae glomerulosa and fasciculata. After 4 1/2 days there was, in the three zones, an increase in the volumetric density of the mitochondria and endoplasmic reticulum and an increase in the mitochondrial surface density which were significant in most cases; the volumetric and surface densities of the lipid droplets increased except in the zona juxtamedullaris. These data suggest a decrease in the adrenal metabolic activity during the first days of life, which increases thereafter until reaching normal values." @default.
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- W2036207428 date "1981-08-01" @default.
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- W2036207428 title "Postnatal development of the rat adrenal cortex: an ultrastructural morphometric study" @default.
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- W2036207428 doi "https://doi.org/10.1016/s0022-5320(81)80019-6" @default.
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