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- W2036223015 abstract "The pathogenesis of neuropsychiatric lupus (NP-SLE) is unclear, but may involve vasculopathy, antibodies against nervous system tissue, or both. A major difficulty in determining the significance of antineuronal antibodies in NP-SLE has been lack of consistent clinical diagnostic approaches. By utilizing a new clinical classification of NP-SLE, neuropsychological assessments, and an assay for IgG antineuronal antibodies, we have found a significant association between antibody-positivity and cognitive impairment or nonfocal NP-SLE. These observations indicate that antineuronal antibodies may play a role in NP-SLE and emphasize the clinical importance of cognitive function in patients with SLE." @default.
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- W2036223015 date "1987-03-01" @default.
- W2036223015 modified "2023-09-24" @default.
- W2036223015 title "Neuronal antibodies and cognitive function in systemic lupus erythematosus" @default.
- W2036223015 doi "https://doi.org/10.1212/wnl.37.3.464" @default.
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