FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036241566> ?p ?o ?g. }

• W2036241566 endingPage "6898" @default.
• W2036241566 startingPage "6894" @default.
• W2036241566 abstract "A continuous lysing and resealing procedure with erythrocytes permitted incorporation in these cells of inositol hexaphosphate (InsP6), a strong allosteric effector of Hb. This leads to significant rightward shifts of the HbO2 dissociation curves with in vitro P50 (partial pressure of O2 at 50% Hb saturation), values increasing from 32.2 +/- 1.8 torr for control erythrocytes to 86 +/- 60 torr (pH 7.40; PCO2 40 torr at 37 degrees C; 1 torr = 1.333 X 10(2) Pa). The shape of the dissociation curve was still sigmoidal, although the Hill coefficient was decreased. The life span of InsP6-loaded erythrocytes equaled that of control erythrocytes. The long-term physiological effects of the InsP6-loaded erythrocytes on piglets were increased O2 release and reduced cardiac output. The reduced O2 affinity of the InsP6-loaded erythrocytes was still effective 20 days after transfusion in awake piglets. The electrolyte concentration appeared stable over the 5-day observation period except for a transient, but significant, hyperkalemia immediately after transfusion. The reductions in the O2 affinity of Hb reported here are large compared with previously reported values. Introduction of InsP6 into viable erythrocytes improves tissue oxygenation when, for any reason, normal blood flow is impaired." @default.
• W2036241566 created "2016-06-24" @default.
• W2036241566 creator A5011191932 @default.
• W2036241566 creator A5052212772 @default.
• W2036241566 creator A5065396653 @default.
• W2036241566 creator A5079728410 @default.
• W2036241566 date "1987-10-01" @default.
• W2036241566 modified "2023-10-08" @default.
• W2036241566 title "Long-term physiological effects of enhanced O2 release by inositol hexaphosphate-loaded erythrocytes." @default.
• W2036241566 cites W1211371770 @default.
• W2036241566 cites W1974186841 @default.
• W2036241566 cites W2018717397 @default.
• W2036241566 cites W2032952791 @default.
• W2036241566 cites W2053982041 @default.
• W2036241566 cites W2113974771 @default.
• W2036241566 cites W2196327977 @default.
• W2036241566 cites W2257188884 @default.
• W2036241566 cites W2265375478 @default.
• W2036241566 cites W2308666986 @default.
• W2036241566 cites W2408986877 @default.
• W2036241566 cites W2410092891 @default.
• W2036241566 cites W2415676689 @default.
• W2036241566 cites W279585398 @default.
• W2036241566 cites W190353619 @default.
• W2036241566 doi "https://doi.org/10.1073/pnas.84.19.6894" @default.
• W2036241566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/299191" @default.
• W2036241566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3116545" @default.
• W2036241566 hasPublicationYear "1987" @default.
• W2036241566 type Work @default.
• W2036241566 sameAs 2036241566 @default.
• W2036241566 citedByCount "34" @default.
• W2036241566 countsByYear W20362415662012 @default.
• W2036241566 countsByYear W20362415662013 @default.
• W2036241566 countsByYear W20362415662015 @default.
• W2036241566 countsByYear W20362415662017 @default.
• W2036241566 countsByYear W20362415662020 @default.
• W2036241566 countsByYear W20362415662021 @default.
• W2036241566 countsByYear W20362415662022 @default.
• W2036241566 crossrefType "journal-article" @default.
• W2036241566 hasAuthorship W2036241566A5011191932 @default.
• W2036241566 hasAuthorship W2036241566A5052212772 @default.
• W2036241566 hasAuthorship W2036241566A5065396653 @default.
• W2036241566 hasAuthorship W2036241566A5079728410 @default.
• W2036241566 hasBestOaLocation W20362415662 @default.
• W2036241566 hasConcept C102931765 @default.
• W2036241566 hasConcept C104317684 @default.
• W2036241566 hasConcept C121332964 @default.
• W2036241566 hasConcept C12554922 @default.
• W2036241566 hasConcept C126322002 @default.
• W2036241566 hasConcept C127503593 @default.
• W2036241566 hasConcept C134018914 @default.
• W2036241566 hasConcept C147789679 @default.
• W2036241566 hasConcept C170493617 @default.
• W2036241566 hasConcept C185592680 @default.
• W2036241566 hasConcept C2777140959 @default.
• W2036241566 hasConcept C2777427919 @default.
• W2036241566 hasConcept C2778917026 @default.
• W2036241566 hasConcept C2780243291 @default.
• W2036241566 hasConcept C30646810 @default.
• W2036241566 hasConcept C55493867 @default.
• W2036241566 hasConcept C71924100 @default.
• W2036241566 hasConcept C77562769 @default.
• W2036241566 hasConcept C86339819 @default.
• W2036241566 hasConcept C86803240 @default.
• W2036241566 hasConcept C97355855 @default.
• W2036241566 hasConcept C98270193 @default.
• W2036241566 hasConceptScore W2036241566C102931765 @default.
• W2036241566 hasConceptScore W2036241566C104317684 @default.
• W2036241566 hasConceptScore W2036241566C121332964 @default.
• W2036241566 hasConceptScore W2036241566C12554922 @default.
• W2036241566 hasConceptScore W2036241566C126322002 @default.
• W2036241566 hasConceptScore W2036241566C127503593 @default.
• W2036241566 hasConceptScore W2036241566C134018914 @default.
• W2036241566 hasConceptScore W2036241566C147789679 @default.
• W2036241566 hasConceptScore W2036241566C170493617 @default.
• W2036241566 hasConceptScore W2036241566C185592680 @default.
• W2036241566 hasConceptScore W2036241566C2777140959 @default.
• W2036241566 hasConceptScore W2036241566C2777427919 @default.
• W2036241566 hasConceptScore W2036241566C2778917026 @default.
• W2036241566 hasConceptScore W2036241566C2780243291 @default.
• W2036241566 hasConceptScore W2036241566C30646810 @default.
• W2036241566 hasConceptScore W2036241566C55493867 @default.
• W2036241566 hasConceptScore W2036241566C71924100 @default.
• W2036241566 hasConceptScore W2036241566C77562769 @default.
• W2036241566 hasConceptScore W2036241566C86339819 @default.
• W2036241566 hasConceptScore W2036241566C86803240 @default.
• W2036241566 hasConceptScore W2036241566C97355855 @default.
• W2036241566 hasConceptScore W2036241566C98270193 @default.
• W2036241566 hasIssue "19" @default.
• W2036241566 hasLocation W20362415661 @default.
• W2036241566 hasLocation W20362415662 @default.
• W2036241566 hasLocation W20362415663 @default.
• W2036241566 hasLocation W20362415664 @default.
• W2036241566 hasOpenAccess W2036241566 @default.
• W2036241566 hasPrimaryLocation W20362415661 @default.
• W2036241566 hasRelatedWork W121610396 @default.
• W2036241566 hasRelatedWork W161121552 @default.
• W2036241566 hasRelatedWork W2019981180 @default.

• next