FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036266069> ?p ?o ?g. }

• W2036266069 endingPage "453" @default.
• W2036266069 startingPage "445" @default.
• W2036266069 abstract "Early observations, candidate gene studies and, more recently, genome-wide association studies have shown that susceptibility to tuberculosis has a host genetic component. Because the value of candidate gene studies has been doubted due to major limitations such as lack of sufficient power and small study groups, lack of reproducibility in independent groups and, often, ambiguous or even contrasting results in attempts of replication, much hope and expectancy has been put on the progress the genome-wide association approach has created. However, much less than initially expected became clear by the results obtained in genome-wide studies, emphasizing the need of increasing sample sizes, e.g. through meta-analyses, and of increasing the density of genetic variants studied across the human genome. A further reason why a rather low number of associated genetic variants were identified to date in infectious diseases in general and tuberculosis in particular might be the fact that selection acts strongly in diseases that affect the reproductive success. As in most genome-wide association studies performed so far, significant signals, often most likely surrogate marker only, have been found in non-coding regions of genomes, the identification of truly causative genetic variation and of the functionality of associated factors needs urgent attention. In the following we briefly discuss genetic studies in tuberculosis and describe new technologies that are currently employed in the search for responsible genetic elements involved in tuberculosis susceptibility." @default.
• W2036266069 created "2016-06-24" @default.
• W2036266069 creator A5011444974 @default.
• W2036266069 creator A5034347475 @default.
• W2036266069 date "2014-12-01" @default.
• W2036266069 modified "2023-10-14" @default.
• W2036266069 title "Host genetic studies in adult pulmonary tuberculosis" @default.
• W2036266069 cites W1551600243 @default.
• W2036266069 cites W1970910747 @default.
• W2036266069 cites W1971833707 @default.
• W2036266069 cites W1979692277 @default.
• W2036266069 cites W1980991473 @default.
• W2036266069 cites W1984944701 @default.
• W2036266069 cites W1985564274 @default.
• W2036266069 cites W1985739089 @default.
• W2036266069 cites W1985849948 @default.
• W2036266069 cites W1989419347 @default.
• W2036266069 cites W1991027233 @default.
• W2036266069 cites W1991269963 @default.
• W2036266069 cites W1992241358 @default.
• W2036266069 cites W1993764924 @default.
• W2036266069 cites W1996491681 @default.
• W2036266069 cites W2007021820 @default.
• W2036266069 cites W2009880385 @default.
• W2036266069 cites W2015177444 @default.
• W2036266069 cites W2017852917 @default.
• W2036266069 cites W2022667850 @default.
• W2036266069 cites W2023742867 @default.
• W2036266069 cites W2039227742 @default.
• W2036266069 cites W2039705224 @default.
• W2036266069 cites W2041313118 @default.
• W2036266069 cites W2042103448 @default.
• W2036266069 cites W2051816266 @default.
• W2036266069 cites W2055577456 @default.
• W2036266069 cites W2060842569 @default.
• W2036266069 cites W2061314812 @default.
• W2036266069 cites W2063504630 @default.
• W2036266069 cites W2064306519 @default.
• W2036266069 cites W2070407983 @default.
• W2036266069 cites W2071640547 @default.
• W2036266069 cites W2080896009 @default.
• W2036266069 cites W2082305090 @default.
• W2036266069 cites W2087036932 @default.
• W2036266069 cites W2088614821 @default.
• W2036266069 cites W2091643894 @default.
• W2036266069 cites W2101357408 @default.
• W2036266069 cites W2107882288 @default.
• W2036266069 cites W2109642702 @default.
• W2036266069 cites W2116152510 @default.
• W2036266069 cites W2117446594 @default.
• W2036266069 cites W2121662608 @default.
• W2036266069 cites W2122515336 @default.
• W2036266069 cites W2123707618 @default.
• W2036266069 cites W2127513692 @default.
• W2036266069 cites W2134783591 @default.
• W2036266069 cites W2140716261 @default.
• W2036266069 cites W2141459724 @default.
• W2036266069 cites W2148169621 @default.
• W2036266069 cites W2148964874 @default.
• W2036266069 cites W2151846965 @default.
• W2036266069 cites W2152435464 @default.
• W2036266069 cites W2167619252 @default.
• W2036266069 cites W2169294950 @default.
• W2036266069 cites W2171556122 @default.
• W2036266069 cites W2171559660 @default.
• W2036266069 cites W2259938310 @default.
• W2036266069 cites W2315669348 @default.
• W2036266069 cites W2341817708 @default.
• W2036266069 cites W4210967418 @default.
• W2036266069 cites W69136544 @default.
• W2036266069 doi "https://doi.org/10.1016/j.smim.2014.09.005" @default.
• W2036266069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25307123" @default.
• W2036266069 hasPublicationYear "2014" @default.
• W2036266069 type Work @default.
• W2036266069 sameAs 2036266069 @default.
• W2036266069 citedByCount "33" @default.
• W2036266069 countsByYear W20362660692015 @default.
• W2036266069 countsByYear W20362660692016 @default.
• W2036266069 countsByYear W20362660692017 @default.
• W2036266069 countsByYear W20362660692018 @default.
• W2036266069 countsByYear W20362660692019 @default.
• W2036266069 crossrefType "journal-article" @default.
• W2036266069 hasAuthorship W2036266069A5011444974 @default.
• W2036266069 hasAuthorship W2036266069A5034347475 @default.
• W2036266069 hasConcept C104317684 @default.
• W2036266069 hasConcept C106208931 @default.
• W2036266069 hasConcept C135763542 @default.
• W2036266069 hasConcept C141231307 @default.
• W2036266069 hasConcept C142724271 @default.
• W2036266069 hasConcept C153209595 @default.
• W2036266069 hasConcept C186413461 @default.
• W2036266069 hasConcept C197077220 @default.
• W2036266069 hasConcept C2781069245 @default.
• W2036266069 hasConcept C47042493 @default.
• W2036266069 hasConcept C54355233 @default.
• W2036266069 hasConcept C68873052 @default.
• W2036266069 hasConcept C69991583 @default.
• W2036266069 hasConcept C70721500 @default.

• next