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• W2036301606 abstract "<i >Background</i>. The purpose of this study was to evaluate the combination of an enamel matrix derivative (EMD) and an osteoconductive bone ceramic (BC) in improving bone regeneration. <i >Materials and Methods</i>. Four cylindrical cavities (<svg style=vertical-align:-0.3135pt;width:59.625px; id=M1 height=11.2 version=1.1 viewBox=0 0 59.625 11.2 width=59.625 xmlns=http://www.w3.org/2000/svg> <g transform=matrix(1.25,0,0,-1.25,0,11.2)> <g transform=translate(72,-63.04)> <text transform=matrix(1,0,0,-1,-71.95,63.4)> <tspan style=font-size: 12.50px; x=0 y=0>6</tspan> <tspan style=font-size: 12.50px; x=9.0271664 y=0>×</tspan> <tspan style=font-size: 12.50px; x=19.804752 y=0>6</tspan> <tspan style=font-size: 12.50px; x=28.144253 y=0>m</tspan> <tspan style=font-size: 12.50px; x=37.871586 y=0>m</tspan> </text> </g> </g> </svg>) were prepared bilaterally in the mandible in three dogs. The defects were randomly assigned to four different treatments&#x2014;filled with EMD/BC and covered with a nonresorbable membrane, filled with EMD/BC without membrane, membrane coverage only, or control (left untreated)&#x2014;and healed for 2, 4, or 6 weeks. Harvested specimens were prepared for histologic, histomorphometric, and immunohistochemical analyses. <i >Results</i>. Sites treated with EMD/BC with or without membrane showed more total bone formation and lamellar bone formation than membrane-only and control defects. There were no statistically significant differences in total bone formation between EMD/BC with or without membrane. <i >Conclusion</i>. EMD with BC might improve bone formation in osseous defects more than membrane coverage alone; the use of a membrane had no significant additive effect on total bone formation." @default.
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• W2036301606 date "2012-01-01" @default.
• W2036301606 modified "2023-10-13" @default.
• W2036301606 title "The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects: A Histomorphometric and Immunohistochemical Study in the Canine" @default.
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• W2036301606 doi "https://doi.org/10.1100/2012/196791" @default.
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