FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036307573> ?p ?o ?g. }

• W2036307573 endingPage "16" @default.
• W2036307573 startingPage "8" @default.
• W2036307573 abstract "Hematopoietic processes, especially megakaryocytopoiesis and thrombopoiesis, are highly sensitive to high-linear energy transfer (LET) radiations such as heavy-ion beams that have greater biological effects than low-LET radiation. This study examined the terminal maturation of megakaryocytes and platelet production derived from hematopoietic stem cells irradiated with heavy-ion beams. CD34 cells derived from human placental/umbilical cord blood were exposed to monoenergetic carbon-ion beams (LET = 50 keV/µm) and then cultured in a serum-free medium supplemented with thrombopoietin and interleukin-3. There was no significant difference in megakaryocyte-specific markers between nonirradiated control and irradiated cells. Expression of Tie-2, a receptor that acts in early hematopoiesis, showed a significant 1.31-fold increase after 2 Gy irradiation compared to control cells on day 7. There was a significant increase in Tie-2 mRNA expression. In addition, the expression of other mRNAs, such as PECAM1, SELP and CD44, was also significantly increased in cells irradiated with heavy-ion beams. However, the adherent function of platelets derived from the irradiated cells showed no difference from that in the controls. These results clarify that the functions of megakaryocytopoiesis and thrombopoiesis derived from hematopoietic stem/progenitor cells irradiated with heavy-ion beams are similar to those in the unirradiated cells, although heavy-ion beams affect the expression of genes associated with cellular adhesion." @default.
• W2036307573 created "2016-06-24" @default.
• W2036307573 creator A5025552491 @default.
• W2036307573 creator A5041719170 @default.
• W2036307573 creator A5063671942 @default.
• W2036307573 creator A5067945916 @default.
• W2036307573 creator A5072929560 @default.
• W2036307573 date "2011-07-01" @default.
• W2036307573 modified "2023-09-26" @default.
• W2036307573 title "Terminal Maturation of Megakaryocytes and Platelet Production by Hematopoietic Stem Cells Irradiated with Heavy-Ion Beams" @default.
• W2036307573 cites W1596240955 @default.
• W2036307573 cites W1847687345 @default.
• W2036307573 cites W1974155710 @default.
• W2036307573 cites W1980100431 @default.
• W2036307573 cites W1983291717 @default.
• W2036307573 cites W1990632598 @default.
• W2036307573 cites W1997533204 @default.
• W2036307573 cites W1997970567 @default.
• W2036307573 cites W2005653676 @default.
• W2036307573 cites W2029246114 @default.
• W2036307573 cites W2036573425 @default.
• W2036307573 cites W2050806440 @default.
• W2036307573 cites W2060610551 @default.
• W2036307573 cites W2074311041 @default.
• W2036307573 cites W2092614459 @default.
• W2036307573 cites W2103129439 @default.
• W2036307573 cites W2104889636 @default.
• W2036307573 cites W2120810793 @default.
• W2036307573 cites W2123170994 @default.
• W2036307573 cites W2128024099 @default.
• W2036307573 cites W2139405628 @default.
• W2036307573 cites W2144248277 @default.
• W2036307573 cites W2146399077 @default.
• W2036307573 cites W2163903153 @default.
• W2036307573 cites W2172533783 @default.
• W2036307573 cites W2402622457 @default.
• W2036307573 doi "https://doi.org/10.1667/rr2392.1" @default.
• W2036307573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21529146" @default.
• W2036307573 hasPublicationYear "2011" @default.
• W2036307573 type Work @default.
• W2036307573 sameAs 2036307573 @default.
• W2036307573 citedByCount "4" @default.
• W2036307573 countsByYear W20363075732013 @default.
• W2036307573 countsByYear W20363075732014 @default.
• W2036307573 crossrefType "journal-article" @default.
• W2036307573 hasAuthorship W2036307573A5025552491 @default.
• W2036307573 hasAuthorship W2036307573A5041719170 @default.
• W2036307573 hasAuthorship W2036307573A5063671942 @default.
• W2036307573 hasAuthorship W2036307573A5067945916 @default.
• W2036307573 hasAuthorship W2036307573A5072929560 @default.
• W2036307573 hasConcept C109159458 @default.
• W2036307573 hasConcept C111337013 @default.
• W2036307573 hasConcept C121332964 @default.
• W2036307573 hasConcept C153911025 @default.
• W2036307573 hasConcept C185544564 @default.
• W2036307573 hasConcept C185592680 @default.
• W2036307573 hasConcept C201750760 @default.
• W2036307573 hasConcept C203014093 @default.
• W2036307573 hasConcept C2776958478 @default.
• W2036307573 hasConcept C2777863708 @default.
• W2036307573 hasConcept C2777918643 @default.
• W2036307573 hasConcept C2779705218 @default.
• W2036307573 hasConcept C28328180 @default.
• W2036307573 hasConcept C86803240 @default.
• W2036307573 hasConcept C89560881 @default.
• W2036307573 hasConcept C95444343 @default.
• W2036307573 hasConceptScore W2036307573C109159458 @default.
• W2036307573 hasConceptScore W2036307573C111337013 @default.
• W2036307573 hasConceptScore W2036307573C121332964 @default.
• W2036307573 hasConceptScore W2036307573C153911025 @default.
• W2036307573 hasConceptScore W2036307573C185544564 @default.
• W2036307573 hasConceptScore W2036307573C185592680 @default.
• W2036307573 hasConceptScore W2036307573C201750760 @default.
• W2036307573 hasConceptScore W2036307573C203014093 @default.
• W2036307573 hasConceptScore W2036307573C2776958478 @default.
• W2036307573 hasConceptScore W2036307573C2777863708 @default.
• W2036307573 hasConceptScore W2036307573C2777918643 @default.
• W2036307573 hasConceptScore W2036307573C2779705218 @default.
• W2036307573 hasConceptScore W2036307573C28328180 @default.
• W2036307573 hasConceptScore W2036307573C86803240 @default.
• W2036307573 hasConceptScore W2036307573C89560881 @default.
• W2036307573 hasConceptScore W2036307573C95444343 @default.
• W2036307573 hasIssue "1" @default.
• W2036307573 hasLocation W20363075731 @default.
• W2036307573 hasLocation W20363075732 @default.
• W2036307573 hasOpenAccess W2036307573 @default.
• W2036307573 hasPrimaryLocation W20363075731 @default.
• W2036307573 hasRelatedWork W130975678 @default.
• W2036307573 hasRelatedWork W1985180260 @default.
• W2036307573 hasRelatedWork W2079384847 @default.
• W2036307573 hasRelatedWork W2144248277 @default.
• W2036307573 hasRelatedWork W2145139769 @default.
• W2036307573 hasRelatedWork W2332253499 @default.
• W2036307573 hasRelatedWork W2344941588 @default.
• W2036307573 hasRelatedWork W2411378646 @default.
• W2036307573 hasRelatedWork W2738894905 @default.
• W2036307573 hasRelatedWork W2953092519 @default.
• W2036307573 hasVolume "176" @default.

• next