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• W2036342907 abstract "Background There has been no report on seasonal changes in Der II allergen in floor and bedding dust. Objective The purpose of the study was to examine the extent of seasonal changes in Der I and Der II allergens in the floor and bedding dust found in houses. Methods We measured the absolute concentrations of mite allergens in dust collected monthly for 1 year from both the floors and bedding of 8 houses in Tokyo. Dust samples were obtained from 8 families without regard to their allergy histories. The concentrations of the Der p I, Der f I, and Der II allergens were measured by fluorometric sandwich ELISA. Results We found seasonal changes in the concentrations of these mite allergens. The highest concentrations of Der I (Der p I plus Der f I) and Der II (Der p II plus Der f II) were present from August to October, and the lowest ones from March to April. In floor dust, the mean highest concentrations of Der I and Der II (35.0 and 20.2 micrograms/g of fine dust) were sevenfold and fivefold respectively, times the mean lowest concentrations. In bedding dust, the mean highest concentrations of Der I and Der II (51.3 and 29.6 micrograms/g of fine dust) each were fourfold times the mean lowest concentrations. Conclusions The patterns of seasonal changes in Der II in floor and bedding dust were similar to those of Der I. There has been no report on seasonal changes in Der II allergen in floor and bedding dust. The purpose of the study was to examine the extent of seasonal changes in Der I and Der II allergens in the floor and bedding dust found in houses. We measured the absolute concentrations of mite allergens in dust collected monthly for 1 year from both the floors and bedding of 8 houses in Tokyo. Dust samples were obtained from 8 families without regard to their allergy histories. The concentrations of the Der p I, Der f I, and Der II allergens were measured by fluorometric sandwich ELISA. We found seasonal changes in the concentrations of these mite allergens. The highest concentrations of Der I (Der p I plus Der f I) and Der II (Der p II plus Der f II) were present from August to October, and the lowest ones from March to April. In floor dust, the mean highest concentrations of Der I and Der II (35.0 and 20.2 micrograms/g of fine dust) were sevenfold and fivefold respectively, times the mean lowest concentrations. In bedding dust, the mean highest concentrations of Der I and Der II (51.3 and 29.6 micrograms/g of fine dust) each were fourfold times the mean lowest concentrations. The patterns of seasonal changes in Der II in floor and bedding dust were similar to those of Der I." @default.
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• W2036342907 date "1996-02-01" @default.
• W2036342907 modified "2023-10-17" @default.
• W2036342907 title "Seasonal Changes in Mite Allergen (Der I and Der II) Concentrations in Japanese Homes" @default.
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• W2036342907 doi "https://doi.org/10.1016/s1081-1206(10)63418-7" @default.
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