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- W2036346385 abstract "The willingness of people with life-threatening diseases to accept treatments with a high risk and possible low gain may be underestimated by health professionals and medical policists. For example, the majority of older, unwell people admitted to hospital wish to have cardio-pulmonary resuscitation, despite a high chance of an unsatisfactory outcome (Potter et al 1994). This is contrary to the perceived wishes of older, well people (Wagner 1984). Similarly, people with newly diagnosed cancer are more willing to accept toxic chemotherapy with low levels of benefit, compared with healthy matched control subjects, doctors and nurses who are more 'risk averse' and place a lower value on available treatment options (Slevin et al J990). The views and priorities of people with more advanced cancer have not been formally studied. It is not known whether (despite having received prior chemotherapy) the search for treatment escalates for these people or whether a degree of acceptance develops with a consequent reduction in the desire for toxic treatment. This inquiry is of particular importance as second-line palliative chemotherapy tends to be less effective, more toxic and more costly than earlier treatment. The influence of factors such as social circumstance, previous experiences of chemotherapy and symptom distress have not been considered. Nevertheless, they may all bias an individual's choice. This paper describes a study in progress which is designed to elicit patients' perspectives of the clinical utility of second-line chemotherapy." @default.
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- W2036346385 date "1998-03-01" @default.
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- W2036346385 title "Investigating the patients' perspective of the clinical utility of second-line chemotherapy" @default.
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- W2036346385 doi "https://doi.org/10.1016/s1462-3889(98)81264-7" @default.
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