Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036363804> ?p ?o ?g. }
- W2036363804 endingPage "1006" @default.
- W2036363804 startingPage "999" @default.
- W2036363804 abstract "This article reviews our current understanding of the role of oxygen free radicals in platelet activation. Several studies have indicated that platelets, in analogy to other circulating blood cells, are able to produce oxygen free radicals, which are likely to play an important role in the mechanism of platelet activation and aggregation. Platelet activation has been obtained with very low, physiologically relevant concentrations of radicals generated chemically, by leukocytes, and by hemoglobin derived from membrane leakage of erythrocytes. Knowledge of the role of reactive species in platelet physiology is relevant because platelets are brought into close contact with other cells capable of producing free radicals, such as neutrophils, macrophages, and endothelial cells, during the formation of thrombus. The physiopatological importance of these findings is high because it is now emerging that free radicals may have a role in the mechanism of atherosclerosis and its thrombotic complications, where the causative role of platelets is well documented. This background suggests therapeutic interventions with antioxidants as antiplatelet agents to improve the pharmacological effect of classical antiplatelet drug such as aspirin. Copyright © 1997 Elsevier Science Inc." @default.
- W2036363804 created "2016-06-24" @default.
- W2036363804 creator A5016068884 @default.
- W2036363804 creator A5070911300 @default.
- W2036363804 creator A5072202763 @default.
- W2036363804 creator A5076129878 @default.
- W2036363804 creator A5081037032 @default.
- W2036363804 date "1997-01-01" @default.
- W2036363804 modified "2023-10-18" @default.
- W2036363804 title "Oxygen Free Radicals and Platelet Activation" @default.
- W2036363804 cites W1491688577 @default.
- W2036363804 cites W1510630022 @default.
- W2036363804 cites W1538759022 @default.
- W2036363804 cites W1542412714 @default.
- W2036363804 cites W1545142973 @default.
- W2036363804 cites W1553503443 @default.
- W2036363804 cites W1568243295 @default.
- W2036363804 cites W1573253342 @default.
- W2036363804 cites W1584532004 @default.
- W2036363804 cites W1585265298 @default.
- W2036363804 cites W1591414362 @default.
- W2036363804 cites W1603668575 @default.
- W2036363804 cites W1742468561 @default.
- W2036363804 cites W1801129364 @default.
- W2036363804 cites W180965172 @default.
- W2036363804 cites W1913374546 @default.
- W2036363804 cites W1965951138 @default.
- W2036363804 cites W1966562996 @default.
- W2036363804 cites W1968243691 @default.
- W2036363804 cites W1974864450 @default.
- W2036363804 cites W1976210633 @default.
- W2036363804 cites W1979034912 @default.
- W2036363804 cites W1982431196 @default.
- W2036363804 cites W1987812557 @default.
- W2036363804 cites W1988032789 @default.
- W2036363804 cites W1988384356 @default.
- W2036363804 cites W1999512126 @default.
- W2036363804 cites W2009374304 @default.
- W2036363804 cites W2017647845 @default.
- W2036363804 cites W2019814232 @default.
- W2036363804 cites W2022037486 @default.
- W2036363804 cites W2023887745 @default.
- W2036363804 cites W2023922308 @default.
- W2036363804 cites W2027259889 @default.
- W2036363804 cites W2030601585 @default.
- W2036363804 cites W2037564556 @default.
- W2036363804 cites W2037854429 @default.
- W2036363804 cites W2040745838 @default.
- W2036363804 cites W2043840414 @default.
- W2036363804 cites W2048777870 @default.
- W2036363804 cites W2051281245 @default.
- W2036363804 cites W2058137293 @default.
- W2036363804 cites W2061045250 @default.
- W2036363804 cites W2061857895 @default.
- W2036363804 cites W2062483277 @default.
- W2036363804 cites W2066502016 @default.
- W2036363804 cites W2073141866 @default.
- W2036363804 cites W2080431414 @default.
- W2036363804 cites W2083457751 @default.
- W2036363804 cites W2085584421 @default.
- W2036363804 cites W2087676726 @default.
- W2036363804 cites W2089964632 @default.
- W2036363804 cites W2092969601 @default.
- W2036363804 cites W2110013248 @default.
- W2036363804 cites W2115686938 @default.
- W2036363804 cites W2120157044 @default.
- W2036363804 cites W2124668291 @default.
- W2036363804 cites W2146388445 @default.
- W2036363804 cites W2150024781 @default.
- W2036363804 cites W2152133730 @default.
- W2036363804 cites W2162414650 @default.
- W2036363804 cites W2168460845 @default.
- W2036363804 cites W2323526343 @default.
- W2036363804 cites W2413166777 @default.
- W2036363804 cites W4241815404 @default.
- W2036363804 cites W4253039236 @default.
- W2036363804 cites W2416339862 @default.
- W2036363804 doi "https://doi.org/10.1016/s0891-5849(96)00488-1" @default.
- W2036363804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9034239" @default.
- W2036363804 hasPublicationYear "1997" @default.
- W2036363804 type Work @default.
- W2036363804 sameAs 2036363804 @default.
- W2036363804 citedByCount "224" @default.
- W2036363804 countsByYear W20363638042012 @default.
- W2036363804 countsByYear W20363638042013 @default.
- W2036363804 countsByYear W20363638042014 @default.
- W2036363804 countsByYear W20363638042015 @default.
- W2036363804 countsByYear W20363638042016 @default.
- W2036363804 countsByYear W20363638042017 @default.
- W2036363804 countsByYear W20363638042018 @default.
- W2036363804 countsByYear W20363638042019 @default.
- W2036363804 countsByYear W20363638042020 @default.
- W2036363804 countsByYear W20363638042021 @default.
- W2036363804 countsByYear W20363638042022 @default.
- W2036363804 countsByYear W20363638042023 @default.
- W2036363804 crossrefType "journal-article" @default.
- W2036363804 hasAuthorship W2036363804A5016068884 @default.
- W2036363804 hasAuthorship W2036363804A5070911300 @default.