FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036395009> ?p ?o ?g. }

• W2036395009 endingPage "111" @default.
• W2036395009 startingPage "93" @default.
• W2036395009 abstract "The paper recalls the experiences of the author over the past forty-eight years in a field which later became known as psychopharmacology. The author began in physical chemistry and traditional pharmacology. His interest in the nervous system stemmed from X-ray diffraction studies on the structure of living myelin, and led, by way of studies on the distribution of cholinesterases and the effects of atropine, to the study of the effects of drugs on the electrical activity of the brain in the conscious animal. At the clinical level it included studies of the effects of drugs on catatonic schizophrenic stupor. These studies took place before the discovery of chlorpromazine. They led to the creation, in 1951, of the Department of Experimental Psychiatry in Birmingham, England, the first department of its kind in the world. The department included neurochemical, electrophysiological, and animal behavior laboratories and a strong clinical facility (the Uffculme Clinic). The first blind trial of chlorpromazine was carried out in that department in 1953 and 1954. The existence of families of neuroregulatory compounds, having uneven distribution in the brain, and exerting regional chemical field effects in relation to function was postulated on the basis of experimental and clinical findings. The work of colleagues and participants in the various studies is gratefully acknowledged in the text. In 1954 the author served as convening executive secretary of the first International Symposium on Neurochemistry at Oxford, England, the first meeting of its kind. He came to the United States in 1957 and founded, and served as first director of, the new Clinical Neuropharmacology Research Center, now the Center for Neuroscience at St. Elizabeth's Hospital, Washington, DC. He directed this program from 1957 to 1963. Subsequent activities at Johns Hopkins, the World Health Organization, and the International Brain Research Organization (IBRO) are recalled. In 1961 he was elected first president of the American College of Neuropsychopharmacology. In looking back, he notes the sparse and personal nature of the field in the late 1940s and early 1950s, its explosive growth in the wake of the major clinical discoveries, and above all, the emergence of a new science through the interaction of neurochemistry, electrophysiology, studies of animal behavior, and the refinement of the clinical trial. He regards the emergence of concepts of regional chemistry of the brain as particularly significant, and feels that psychopharmacology is ideally positioned to act as an intermediary between classical pharmacology and quantum biology. The transdisciplinary nature of psychopharmacology provides a template for a comprehensive psychiatry of the future–a discipline which is now positioned to lead. He also feels that future discoveries in psychopharmacology will pose a most poignant ethical dilemma for medicine, and argues for a timely readying for these responsibilities." @default.
• W2036395009 created "2016-06-24" @default.
• W2036395009 creator A5046845518 @default.
• W2036395009 date "1995-04-01" @default.
• W2036395009 modified "2023-10-18" @default.
• W2036395009 title "Psychopharmacology: Finding One's Way" @default.
• W2036395009 cites W1565565050 @default.
• W2036395009 cites W1581103620 @default.
• W2036395009 cites W171418980 @default.
• W2036395009 cites W180224260 @default.
• W2036395009 cites W1976702307 @default.
• W2036395009 cites W1992795970 @default.
• W2036395009 cites W1994840924 @default.
• W2036395009 cites W1996295585 @default.
• W2036395009 cites W2001588625 @default.
• W2036395009 cites W2002040692 @default.
• W2036395009 cites W2012617950 @default.
• W2036395009 cites W2018261970 @default.
• W2036395009 cites W2019146902 @default.
• W2036395009 cites W2026778141 @default.
• W2036395009 cites W2033516863 @default.
• W2036395009 cites W2034450065 @default.
• W2036395009 cites W2038038269 @default.
• W2036395009 cites W2038939595 @default.
• W2036395009 cites W2039182679 @default.
• W2036395009 cites W2040310415 @default.
• W2036395009 cites W2040455912 @default.
• W2036395009 cites W2045864113 @default.
• W2036395009 cites W2046792484 @default.
• W2036395009 cites W2047204800 @default.
• W2036395009 cites W2052268700 @default.
• W2036395009 cites W2054923626 @default.
• W2036395009 cites W2060337783 @default.
• W2036395009 cites W2068873718 @default.
• W2036395009 cites W2073243463 @default.
• W2036395009 cites W2077251812 @default.
• W2036395009 cites W2089083213 @default.
• W2036395009 cites W2102320556 @default.
• W2036395009 cites W2115463644 @default.
• W2036395009 cites W2133560314 @default.
• W2036395009 cites W2150474919 @default.
• W2036395009 cites W2171116065 @default.
• W2036395009 cites W2198050272 @default.
• W2036395009 cites W2256565300 @default.
• W2036395009 cites W2273386264 @default.
• W2036395009 cites W2296905412 @default.
• W2036395009 cites W2314440009 @default.
• W2036395009 cites W2330783210 @default.
• W2036395009 cites W2405203752 @default.
• W2036395009 cites W2411755101 @default.
• W2036395009 cites W2415994565 @default.
• W2036395009 cites W2416727632 @default.
• W2036395009 cites W2479023366 @default.
• W2036395009 cites W2485799119 @default.
• W2036395009 cites W2490195722 @default.
• W2036395009 cites W2490491189 @default.
• W2036395009 cites W2795831086 @default.
• W2036395009 cites W60431322 @default.
• W2036395009 cites W610409328 @default.
• W2036395009 cites W632738487 @default.
• W2036395009 doi "https://doi.org/10.1016/0893-133x(93)00017-g" @default.
• W2036395009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7779246" @default.
• W2036395009 hasPublicationYear "1995" @default.
• W2036395009 type Work @default.
• W2036395009 sameAs 2036395009 @default.
• W2036395009 citedByCount "6" @default.
• W2036395009 countsByYear W20363950092015 @default.
• W2036395009 countsByYear W20363950092016 @default.
• W2036395009 countsByYear W20363950092018 @default.
• W2036395009 countsByYear W20363950092021 @default.
• W2036395009 crossrefType "journal-article" @default.
• W2036395009 hasAuthorship W2036395009A5046845518 @default.
• W2036395009 hasBestOaLocation W20363950091 @default.
• W2036395009 hasConcept C103709681 @default.
• W2036395009 hasConcept C11171543 @default.
• W2036395009 hasConcept C118552586 @default.
• W2036395009 hasConcept C15744967 @default.
• W2036395009 hasConcept C16568411 @default.
• W2036395009 hasConcept C169760540 @default.
• W2036395009 hasConcept C184117892 @default.
• W2036395009 hasConcept C25876315 @default.
• W2036395009 hasConcept C39920043 @default.
• W2036395009 hasConcept C61535369 @default.
• W2036395009 hasConcept C71924100 @default.
• W2036395009 hasConceptScore W2036395009C103709681 @default.
• W2036395009 hasConceptScore W2036395009C11171543 @default.
• W2036395009 hasConceptScore W2036395009C118552586 @default.
• W2036395009 hasConceptScore W2036395009C15744967 @default.
• W2036395009 hasConceptScore W2036395009C16568411 @default.
• W2036395009 hasConceptScore W2036395009C169760540 @default.
• W2036395009 hasConceptScore W2036395009C184117892 @default.
• W2036395009 hasConceptScore W2036395009C25876315 @default.
• W2036395009 hasConceptScore W2036395009C39920043 @default.
• W2036395009 hasConceptScore W2036395009C61535369 @default.
• W2036395009 hasConceptScore W2036395009C71924100 @default.
• W2036395009 hasIssue "2" @default.
• W2036395009 hasLocation W20363950091 @default.
• W2036395009 hasLocation W20363950092 @default.

• next